Khoom piav qhia
Cov peptide endothelin constricts cov leeg hauv cov hlab ntsha, ua kom ntshav siab. Ambrisentan, uas ua rau cov leeg no so, yog endothelin receptor antagonist, thiab yog xaiv rau hom A endothelin receptor (ETA). Ambrisentan tau ua kom muaj peev xwm ua tau zoo dua qub (6-feeb taug kev deb) piv nrog cov placebo hauv ob qhov muag tsis pom kev, ntau qhov kev sim siab (ARIES-1 thiab ARIES-2). Zoo li tag nrho cov endothelin receptor antagonists, Ambrisentan yog contraindicated nyob rau hauv cov poj niam cev xeeb tub thiab cov neeg uas tab tom sim xeeb tub, vim muaj peev xwm rau teratogenic cuam tshuam rau tus me nyuam hauv plab.
Ambrisetan, muag raws li lub npe Letairis ntawm lwm tus, yog ib qho tshuaj siv rau kev kho mob ntsws pulmonary hypertension. Nws yog ib qho endothelin receptor antagonist.
Ambrisetantau pom zoo los ntawm US Food and Drug Administration (FDA) thiab European Medicines Agency (EMA), thiab tau xaiv ib qho tshuaj me nyuam ntsuag, rau kev kho mob ntsws pulmonary hypertension.
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:sales4@faithfulbio.com
COA
| Yam khoom | Txuj | Cov qhabnias xeem |
| Qhov tshwm sim | Dawb mus rau dawb hmoov | Ua raws |
| Kev txheeb xyuas | IR | Ua raws |
| Poob rau ziab | Tsawg dua lossis sib npaug rau 5.0% | 0.11% |
| Yam khoom | Ib qho impurity: Tsawg dua lossis sib npaug rau 0.3% | 0.14% |
| Tag nrho cov impurities: Tsawg dua lossis sib npaug rau 1.0% | 0.30% | |
| R-Isomer | Tsawg dua los yog sib npaug rau 0.5% | 0.13% |
| S-2-Hydroxy-3- Methoxy-3, 3-Diphenyl Propionic Acid | Tsawg dua lossis sib npaug rau 0.2% | 0.12% |
| Residual kuab tshuaj | Ua tau raws li qhov yuav tsum tau ua | Ua raws |
| Assay | 98.5~101% | 99.80% |
| Xaus | Ua raws li kev lag luam specification | |
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:sales4@faithfulbio.com
Puas yog sildenafil tib yam li ambrisentan?
Sildenafil yog siv los txhim kho kev tawm dag zog hauv cov neeg mob PAH. Ambrisentan so cov leeg nqaij hauv cov hlab ntsha thiab tseem txhim kho kev tawm dag zog (rau-feeb taug kev deb) hauv cov neeg mob PAH, thaum bosentan muaj cov txheej txheem zoo sib xws ntawm kev ua haujlwm raws li nws txo qis hauv cov hlab ntsws.
Yam tshuaj twg yog ambisentan?
Ambrisentan yog nyob rau hauv ib chav kawm ntawm cov tshuaj hu ua endothelin receptor antagonists.
Bosentan thiab ambisentan yog dab tsi?
Bosentan, ambrisentan, thiab macitentan yog endothelin receptor antagonists (ERAs), tam sim no muaj nyob rau hauv Australia rau kev kho mob pulmonary arterial hypertension (PAH).
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:sales4@faithfulbio.com
vim li cas xaiv peb
Peb lub Hoobkas
Pob
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Qhov zoo |
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3-7 hnub |
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Haum rau qis dua 50kg. |
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7-15 hnub |
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Haum rau ntau tshaj 50kg. |
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15-60 hnub |
Los ntawm Hiav Txwv |
Haum rau ntau tshaj 500kg. |
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:sales4@faithfulbio.com
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