Khoom Taw Qhia
Amlodipine hmoovyog ib tiam tshiab ntawm kev ua yeeb yam ntev, alkaline dihydropyridine calcium channel antagonists thiab tus neeg sawv cev ntawm peb tiam ntawm calcium channel antagonists. Zoo li lwm yam dihydropyridine calcium channel antagonists, nws ua los ntawm ib qhov chaw (N site) ntawm lub cell uas txuas nrog dihydropyridine, cuam tshuam cov khoom ntawm calcium channels. Nws qhov zoo yog qhov pib qeeb, lub sijhawm ua haujlwm ntev, kev tswj hwm yooj yim thiab qee qhov kev mob tshwm sim. Vim nws cov qauv tshwj xeeb thiab cov khoom siv tshuaj, nws tau siv dav hauv kev kho mob ntshav siab thiab angina pectoris.Amlodipine hmoovyog tau li dawb crystals los ntawm ethyl acetate, nrog ib tug melting point ntawm 178-179 degree .
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| amlodipine hmoov Daim duab | amlodipine hmoov MF |
Khoom siv
Amlodipine hmoovyog ib tug ntev-acting calcium channel blocker uas yuav siv tau los kho cov kab mob plawv xws li angina pectoris, kub siab, thiab congestive plawv tsis ua hauj lwm. Amlodipine tuaj yeem txo qhov kev nkag ntawm calcium ions, thiab nws lub peev xwm los inhibit calcium-induced aortic contraction yog ob zaug ntawm nifedipine. Nws tuaj yeem txo qis myocardial contractility, qeeb lub plawv dhia, so vascular du nqaij, txo peripheral tsis kam, thiab txo cov plawv load, yog li txo qis myocardial oxygen noj. Amlodipine kuj tseem tuaj yeem nthuav dav cov hlab ntsha epicardial thiab endocardial coronary arteries, ua kom cov hlab ntsha hauv cov hlab ntsha, txhim kho cov ntshav los yog cov pa oxygen rau cov cheeb tsam ischemic, thiab txo qis angina pectoris los ntawm coronary artery spasm.
Txoj Kev 1: Ethyl chloroacetoacetate, N-benzylaminoethanol thiab sodium hydride react hauv tetrahydrofuran kom tau ethyl 4-(2-benzylaminoethoxy)acetoacetate. Tom qab ntawd hnov mob nrog o-chlorobenzaldehyde, methyl 3-aminobutenoate thiab acetic acid hauv methanol, thiab cov khoom ua tau yog hydrogenated thiab txo kom tau amlodipine. Nws yog salified nrog maleic acid kom tau nws cov txiv neej.
Txoj Kev 2: Ethyl chloroacetoacetate thiab azidoethanol yog condensed nyob rau hauv qhov kev txiav txim ntawm sodium hydride kom tau ethyl 4-(2-azidoethoxy)acetoacetate, uas yog ces cyclized nrog o-chlorobenzaldehyde thiab methyl 3-aminobutenoate, thiab thaum kawg cov pab pawg azido raug txo kom tau amlodipine.HPLC spectrum yog qhia hauv daim duab.
Khoom Specification
| Yam khoom | Specification | Kev tshwm sim |
| Qhov tshwm sim | Dawb crystal hmoov | Dawb crystal hmoov |
| Kev txheeb xyuas | Qhov zoo | Qhov zoo |
| Xim thiab clarity ntawm kev daws | Ntshiab thiab tsis muaj xim | Ntshiab thiab tsis muaj xim |
| Sulfate | Tsawg dua lossis sib npaug rau 0.011% | <0.011% |
| Cov hlau hnyav | Tsawg dua lossis sib npaug li 20ppm | <20ppm |
| Poob rau ziab | Tsawg dua lossis sib npaug rau 1.0% | 0.10% |
| Residue ntawm ignition | Tsawg dua lossis sib npaug rau 0.10% | 0.06% |
| Thiamine | Tsawg dua lossis sib npaug rau 0.2% | 0.05% |
| Yam khoom muaj feem | ||
| Tag nrho | Tsawg dua lossis sib npaug rau 1.0% | 0.46% |
| Tej impurity | Tsawg dua lossis sib npaug rau 0.2% | 0.13% |
| Assay | 98.0% ~102.0% | 99.60% |
| Xaus | Ua raws li tus qauv kev lag luam | |
Yuav Ua Li Cas Kom Tau Txais Cov QauvAmlodipine hmoov?
Txais tos xa ib qho kev nug rausunny@faithfulbio.comtxhua lub sijhawm rau tus qauv dawb yog tias koj xav tau APIAmlodipine hmoov.
Qhov zoo tshaj plaws Amlodipine hmoov Chaw tsim tshuaj paus thiab tsum
Faithfulbio muaj kev paub dhau los hauv kev xa tawm cov ntaub ntawv raw thiab tau tsim kev sib raug zoo thiab kev koom tes ntev nrog peb cov neeg siv khoom. Peb ib txwm muab cov khoom zoo thiab kev pabcuam ua ntej. Yog tias koj muaj cov khoom siv raw khoom xav tau, thov hu rau peb. Peb tuaj yeem lees paub qhov kev txiav txim nrog koj raws li koj qhov yuav khoom ntau. Peb kuj txhawb peb txoj kev koom tes thawj zaug pib los ntawm cov qauv. Tsis tas li ntawd, peb txoj kev thauj mus los sai thiab nyab xeeb kuj ua rau koj tshem tawm cov teeb meem ntawm kev lis kev cai.
Peb muaj kev ntseeg siab ntawm peb cov khoom zoo, tab sis yog tias muaj teeb meem tom qab muag, peb yuav teb sai li sai tau thiab daws lawv nrog koj txoj hauv kev zoo tshaj plaws.
Vim Li Cas Xaiv FaithfulbioAmlodipine hmoov?
Faithfulbio tshwj xeeb hauvAmlodipine hmoovrau ntau xyoo, peb muab cov khoom ntawm tus nqi sib tw, thiab peb cov khoom yog qhov zoo tshaj plaws, vim tias peb nruj heev hauv cov khoom tsim thiab kev sim, thiab muaj kev ua tiav thiab paub tab. Tsis tas li ntawd, peb cov neeg ua haujlwm Cov lus hais rau cov khoom muaj kev sib tw heev.
Muaj ntau txoj kev xa khoom rau koj xaiv
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Tsheb thauj mus los |
Shipping txoj kev |
Cargo hnyav xav tau |
Qhov zoo |
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3-7 hnub |
DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, |
Haum rau qis dua 50kg. |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, |
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7-15 hnub |
Los ntawm Cua |
Haum rau ntau tshaj 50kg. |
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15-60 hnub |
Los ntawm Hiav Txwv |
Haum rau ntau tshaj 500kg. |
ua siab zoo ceeb toom:SivAmlodipine hmoovrau kev tshawb fawb nkaus xwb. Txhua lub tebchaw muaj kev pheej hmoo. Thov nrog koj tus kws kho mob tham thiab kawm txog cov kev tshawb fawb muaj ua ntej siv. Tsis tas li ntawd, cov lus piav qhia saum toj no ntawm qhov sib xyaw yog los ntawm cov ntaub ntawv online. Yog tias muaj kev ua txhaum cai, thov hu rau peb kom tshem tawm.
Yuav Amlodipine hmoov nyob qhov twg?
Cia li xa email rausunny@faithfulbio.com, lossis xa koj qhov yuav tsum tau ua hauv daim ntawv hauv qab, peb muaj kev pabcuam txhua lub sijhawm!
Cim npe nrov: amlodipine hmoov cas 88150-42-9, Suav teb, lwm tus neeg, manufacturers, hoobkas, customized, lag luam wholesale, yuav, nqe, tej, ntshiab, tsim, luv nqi, muag, Tshuag, dawb qauv, raw hmoov, raw khoom, ua nyob rau hauv Tuam Tshoj