Esomeprazole magnesium yog S daim ntawv ntawm omeprazole thiab ib tug nquag siv proton twj tso kua mis inhibitor nyob rau hauv kev kho mob xyaum, uas txo gastric acid secretion los ntawm ib tug tshwj xeeb lub hom phiaj mechanism ntawm kev txiav txim. NtshiabEsomeprazole magnesium trihydrate hmoovyog ib yam khoom dawb los yog tawm dawb crystalline uas yog me ntsis soluble hauv dej.
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Cov khoom |
Specifications |
Cov txiaj ntsig |
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Qhov tshwm sim |
dawb los yog me ntsis xim hmoov, me ntsis hygroscopic |
hmoov dawb, me ntsis hygroscopic |
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Kev txheeb xyuas |
A.Infraed absorption spectrophotometric Kev sib piv: Esomeprazole magnesium Trihydrate CRS B.Atomic absorption spectrometry raws li tau piav qhia hauv kev sim rau magnesium |
Ua raws Ua raws |
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Xim ntawm kev daws |
Lub absorbance tsis ntau tshaj 0.2 |
0.05 |
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Chromatographic purity |
Omeprazole N-oxide Tsawg dua lossis sib npaug rau 0.1% Omeprazole Sulfone Tsawg dua lossis sib npaug rau 0.2% Txhua qhov tsis tau qhia txog Impurity Tsawg dua lossis sib npaug rau {{0}}.1% Tag Nrho Cov Tsis Muaj Peev Xwm Tsawg dua lossis sib npaug rau 0.5% |
0.02% 0.08% Raws li 0.12% |
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Enantiomeric purity |
R-enantiomer Tsawg dua lossis sib npaug rau 0.2% |
0.08% |
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Magnesium |
3.30% -3.55% (anhydrous khoom) |
3.46% |
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Dej |
6.0%-8.0% |
6.82% |
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Residual kuab tshuaj |
Acetone: Tsawg dua lossis sib npaug rau 0.5% Methanol: Tsawg dua lossis sib npaug rau 0.3% Ethyl acetate: Tsawg dua lossis sib npaug rau 0.5% |
0.005% 0.011% 0.012% |
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Assay |
98. 0-102. |
99.5% |
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Xaus: Cov khoom no ua raws li USP35. |
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Kev ua tau zoo thiab kev ua haujlwm ntawm esomeprazole magnesium enteric-coated ntsiav tshuaj?
Cov khoom xyaw nquag ntawm esomeprazole magnesium enteric coated ntsiav tshuaj yog esomeprazole magnesium (trihydrate), uas yog ib qho exosome inhibitor uas tuaj yeem inhibit H + / K+- ATPase kev ua, yog li thaiv cov exosome tso tawm. Clinically, nws yog tsuas yog siv los kho cov kab mob digestive xws li gastric ulcers, duodenal ulcers, thiab reflux esophagitis tshwm sim los ntawm ntau gastric acid secretion.
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| 161973-10-0 Esomeprazole magnesium | 217087-09-7 Esomeprazole magnesium trihydrate |
1. Siv rau kab mob gastroesophageal reflux, nrog rau kev pib thiab kev kho mob ntawm erosive esophagitis; Cov khoom no tuaj yeem tswj cov tsos mob xws li acid reflux thiab kub siab rau cov neeg mob;
2. Kev sib xyaw cov tshuaj tua kab mob tsim nyog tuaj yeem tshem tawm Helicobacter pylori, xws li kho cov kab mob duodenal los ntawm tus kab mob Helicobacter pylori, thiab tseem tiv thaiv kev rov tshwm sim ntawm Helicobacter pylori ntsig txog kab mob plab hnyuv;
3. Yog tias cov neeg mob hnyav xav tiv thaiv qhov mob plab hnyuv loj uas tshwm sim los ntawm ntau lub xeev kev ntxhov siab, esomeprazole magnesium tuaj yeem raug xaiv los txo lawv qhov mob thiab yooj yim tswj kev mob plab hnyuv loj.
Nws yog tsim nyog sau cia tias kev siv ntawmEsomeprazole magnesium trihydratetuaj yeem txo cov tsos mob, npog qhov mob, thiab tuaj yeem ncua kev kho mob ib txwm muaj. Yog li ntawd, ua ntej kuaj cov kab mob xws li gastric ulcers, qog markers thiab gastroscopy kuaj yuav tsum ua kom tiav. Tshem tawm cov teeb meem xws li mob plab hnyuv.
Dab tsi yog qhov txawv ntawm omeprazole thiab esomeprazole magnesium?
1.Nyob rau hauv cov qauv, omeprazole thiab Esomeprazole magnesium tuaj yeem hais tau zoo sib xws, zoo ib yam, tab sis cov neeg siv khoom paub chiral isomers paub nws. Feem ntau, tsuas yog ib hom optical isomer tau siv tau. Hauv omeprazole, R-hom thiab S-hom optical isomers yog sib xyaw 1: 1. Esomeprazole magnesium yog ib qho muaj zog tshaj S-isomer ntawmomeprazole, tshem tawm qhov tsis zoo R-isomer. Qhov kev ua kom yooj yim no ua rau muaj zog tiv thaiv cov kua qaub, ua haujlwm ntev ntev, thiab txo cov kev mob tshwm sim ntawm cov khoom.
2.Omeprazole enteric coated capsules yog tsim rau cov kab mob gastric ulcers, duodenal ulcers, stress ulcers, Reflux esophagitis thiab Zhuo-Ai syndrome (gastrinoma), tab sis yuav tsum tau ib tug kws kho mob qhov kev kuaj mob ua ntej siv. Yog tias cov kua qaub ntau dhau yog tshwm sim los ntawm kev noj zaub mov tsis raug thiab koj xav txo cov tsos mob xws li kub siab thiab acid reflux, koj tuaj yeem siv cov khoom no ntawm koj tus kheej yam tsis tau txais kev tso cai ntawm kws kho mob, tab sis koj yuav tsum ua raws li cov lus qhia ntawm cov khoom.Rau cov kev siv niaj hnub siv. Esomeprazole magnesium trihydrate, xws li kev tswj cov tsos mob ntawm GERD, thov xa mus rau qhov ua tau zoo thiab cov teebmeem saum toj no. Txawm li cas los xij, yog tias koj xav tau txuas ntxiv siv cov khoom siv tshuaj tiv thaiv kab mob nonsteroidal los kho koj tus mob, nws raug nquahu kom siv lawv ua ke nrogesomeprazole magnesium enteric coated ntsiav tshuaj. Vim hais tias nonsteroidal anti-inflammatory tshuaj xws liibuprofen, diclofenac, Indomethacinthiab lwm yam. inhibit prostaglandin synthesis, ua puas lub plab hnyuv mucosa, thiab siv mus ntev yuav yooj yim induce peptic ulcers.Peb lub tuam txhab tsis tau tsuas yog muab cov khoom muaj feem xyuam rau Esomeprazole, xws li Omeprazole; Esomeprazole magnesium trihydrate; Peb tuaj yeem muab cov khoom NSAID xws li ibuprofen, diclofenac,Indomethacin, thiab lwm yam Yog tias koj muaj kev npaj yuav khoom, thov hu rau peb ntawmemail:sales6@faithfulbio.com.
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| 73590-58-6 Omeprazole | 119141-88-7 Esomeprazole |
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| 15687-27-1 ibuprofen | 15307-86-5 diclofenac | 53-86-1 Indomethacin |
Hais txog kev sib txuam tshuaj ntawm cov khoom no
Qee cov tshuaj yuav cuam tshuam nrog esomeprazole magnesium trihydrate, suav nrog cov tshuaj noj, tshuaj tom khw, tshuaj tiv thaiv, vitamins, tshuaj suav tshuaj thiab lwm yam. Thov sab laj nrog kws kho mob ua ntej siv cov tshuaj no nrog esomeprazole magnesium trihydrate.
1. Thaum ua ke nrogclarithromycin, Cheeb Tsam Hauv Qab Kab Ntsig (AUC) ntawm esomeprazole magnesium trihydrate yog ob npaug, tab sis nws tsis tsim nyog los kho nws qhov ntau npaum li cas.
2. Lub plasma concentration ntawm phenytoin nce 13% thaum cov neeg mob qaug dab peg ua ke nrog esomeprazole magnesium trihydrate 40 mg thiabphenytoinYog li nws tau pom zoo los saib xyuas cov ntshav plasma concentration ntawm phenytoin.
3. Thaum kho nrog esomeprazole magnesium trihydrate, vim qhov txo qis ntawm gastric acid secretion, qhov nqus ntawm qee cov tshuaj cuam tshuam los ntawm gastric acid tuaj yeem hloov pauv (piv txwv li, kev nqus ntawm cov kua qaub.ketoconazole, itraconazolethiab hlau tuaj yeem txo tau).
Muaj ntau txoj kev xa khoom rau koj xaiv
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Tsheb thauj mus los |
Shipping txoj kev |
Cargo hnyav xav tau |
Qhov zoo |
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3-7 hnub |
DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, |
Haum rau qis dua 50kg. |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, |
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7-15 hnub |
Los ntawm Cua |
Haum rau ntau tshaj 50kg. |
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15-60 hnub |
Los ntawm Hiav Txwv |
Haum rau ntau tshaj 500kg. |
Peb lub zog:
Peb lub tuam txhab tau dhau los ntawm FDA thiab ISO19001 kev tswj hwm qhov system ntawv pov thawj. Thiab peb muaj kev koom tes nrog kev cog lus nrog ntau lub chaw tsim khoom thiab chaw soj nstuam hauv Suav teb, tuaj yeem muab tus nqi zoo rau koj.Peb lub tuam txhab tsis tuaj yeem muab cov khoom lag luam ntsig txog Esomeprazole, xws li Omeprazole;Esomeprazole magnesium trihydrate; Peb kuj tuaj yeem muab cov khoom NSAID xws li ibuprofen, diclofenac, Indomethacin, thiab lwm yam. Yog tias koj txaus siab, thov qhia rau peb.
Peb tsis tsuas yog muaj qhov tshwj xeeb zoo hauv kev thauj mus los, tab sis kuj txhawb ntau txoj hauv kev them nyiaj, txawm tias koj siv nyiaj US, euros, Australian las, lossis cov nyiaj hauv zos los ntawm Singapore, Malaysia, Thaib, thiab lwm yam. Peb kuj tuaj yeem txhawb cov txiaj ntsig hauv zos hauv cov cheeb tsam thiab cov tebchaws no. Tsis tas li ntawd, peb kuj txhawb nqa cov npav hauv txhab nyiaj (credit cards, thiab lwm yam) rau kev them nyiaj.
Tsis lees paub: Cov ntaub ntawv luam tawm ntawm lub vev xaib no los ntawm Is Taws Nem, tsis tau txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm cov ntsiab lus. Thov ua tib zoo saib kom paub qhov txawv. Tsis tas li ntawd, cov khoom muab los ntawm peb lub tuam txhab tsuas yog siv rau kev tshawb fawb tshawb fawb. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv tsis raug.
Yog tias koj txaus siab rau peb cov khoom, lossis muaj cov lus qhia tseem ceeb ntawm peb cov khoom lossis tsis txaus siab rau cov khoom tau txais, thov hu rau peb los ntawmEmail :sales6@faithfulbio.com . Peb pab neeg tau cog lus los ua kom tiav kev txaus siab ntawm cov neeg siv khoom.
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