Glibenclamide yog dab tsi?
Glibenclamide hmoovyog dawb crystalline hmoov; Yuav luag tsis muaj ntxhiab. Me ntsis soluble hauv chloroform, me ntsis soluble hauv ethanol, acetone thiab chloroform, insoluble hauv dej los yog ether.
Glibenclamide yog cov tshuaj hypoglycemic, feem ntau yog siv rau cov neeg mob ntshav qab zib hom 2. Nws belongs rau sulfonylurea. Ib qho ntawm cov laj thawj ntawm hom 2 mob ntshav qab zib mellitus yog tias insulin tsim los ntawm islet hlwb hauv lub cev raug txo, thiab insulin tuaj yeem txo cov ntshav qab zib. Yog tias qib insulin txo qis, cov ntshav qab zib hauv tib neeg lub cev yuav nce thiab ua rau muaj ntshav qab zib. Glibenclamide tuaj yeem ua rau cov hlwb ua haujlwm ua haujlwm los tsim cov tshuaj insulin thiab nce qib insulin hauv lub cev, yog li nws tuaj yeem ua lub luag haujlwm hauv kev txo cov ntshav qab zib. Vim tias qhov ua rau mob ntshav qab zib hom 1 yog qhov ua tiav ntawm kev ua haujlwm ntawm cov tshuaj insulin, txawm tias siv Glibenclamide tsis tuaj yeem tsim cov islet hlwb los tsim cov tshuaj insulin, yog li Glibenclamide tsis zoo rau hom 1 mob ntshav qab zib. Nws tsuas yog siv tau rau hom 2 mob ntshav qab zib mellitus nrog qee cov islet muaj nuj nqi.
| Khoom npe | Glibenclamide |
| CAS | 10238-21-8 |
| Cov mis mos molecular | C23H28ClN3O5S |
| Molecular hnyav | 494 |
| EINECS Number | 233-570-6 |
| Kev cia khoom | 2-8 degree |
| Melting point | 173-175 degree |
| Solubility | Ethanol: soluble 2 mg/mL. |
| Qhov tshwm sim | Dawb hmoov |
| Qhov ntom | 1.1805 (zeeg) |
| Kev ruaj ntseg | Nws tuaj yeem khaws cia hauv DMSO lossis ethanol tov ntawm -20 mus txog 3 lub hlis. |
Glibenclamide ua haujlwm li cas?
Khoom Specification
| Yam khoom | Specification | Cov txiaj ntsig |
| Qhov tshwm sim | Hmoov | Ua raws |
| Xim | Dawb hmoov hmoov | Ua raws |
| Particle Loj | 100% dhau 80 mesh | Ua raws |
| Oder | Yam ntxwv | Ua raws |
| Saj | Yam ntxwv | Ua raws |
| Poob rau ziab | Tsawg dua lossis sib npaug rau 5.0% | 2.20% |
| Residue ntawm Ignition | Tsawg dua lossis sib npaug rau 0.1% | 0.05% |
| Residual acetone | Tsawg dua lossis sib npaug rau 0.1% | Ua raws |
| Residual Ethanol | Tsawg dua lossis sib npaug rau 0.5% | Ua raws |
| Heave Mentals | Tsawg dua lossis sib npaug li 10ppm | Ua raws |
| Na | Tsawg dua lossis sib npaug rau 0.1% | <0.1% |
| Pb | Tsawg dua lossis sib npaug li 3 ppm | Ua raws |
| Total Phaj | <1000CFU/g | Ua raws |
| Poov & Pwm | <100 CFU /g | Ua raws |
| E. Coli | Tsis zoo | Ua raws |
| Salmonella | Tsis zoo | Ua raws |
| Xaus: Ua raws li USP Standard | ||
Lub luag haujlwm tseem ceeb ntawm Glibenclamide yog dab tsi?
Glibenclamide yog sulfonylurea cov tshuaj hypoglycemic nrog cov nyhuv hypoglycemic muaj zog, feem ntau hauv ntau yam:
1. Txhawb cov islet cells kom tso cov tshuaj insulin, tab sis muaj qhov yuav tsum tau ua ua ntej uas cov islet hlwb hauv tib neeg lub cev kuj muaj qee yam kev ua haujlwm ntawm synthesizing thiab secreting insulin.
Qhov thib ob, txo cov ntshav qab zib los ntawm kev nce qib ntawm insulin hauv cov hlab ntsha portal.
Thib peb, nws ncaj qha ua rau daim siab, inhibiting decomposition ntawm hepatic glycogen thiab glycogen heterogenesis, ua rau kom txo qis cov piam thaj hauv siab thiab tso zis, yog li txo cov ntshav qab zib.
Thib plaub, ua kom cov rhiab heev ntawm cov ntaub so ntswg extrapancreatic rau insulin thiab kev siv cov suab thaj, yog li txo cov ntshav qab zib.
Yog li ntawd,Glibenclamide hmoovtuaj yeem txo cov ntshav qabzib sai thiab qabzib cov ntshav qabzib.
HTML5 atlas of Glibenclamide
|
|
Puas yog glibenclamide zoo ib yam li metformin?
1, lub mechanism ntawm kev txiav txim yog txawv.
Metformin tuaj yeem txo cov ntshav qabzib feem ntau los ntawm kev txo qis cov piam thaj hauv lub siab thiab ua rau muaj kev nkag siab ntawm cov ntaub so ntswg peripheral rau insulin. Glibenclamide feem ntau ua rau muaj kev tso tawm ntawm insulin hauv lub cev, inhibits cov piam thaj tso zis ntawm lub siab thiab ua rau muaj kev nkag siab ntawm cov ntaub so ntswg peripheral rau insulin.
2. Cov kev phiv tshuaj ntawm cov tshuaj yog txawv.
Metformin tuaj yeem ua rau xeev siab, ntuav, raws plab thiab lwm yam teebmeem tshwm sim. Glibenclamide tej zaum yuav muaj kev phiv xws li xeev siab, raws plab thiab mob taub hau.
3. Txawv taboos
Metformin yog cov tshuaj biguanide hypoglycemic, thiab nws cov contraindications yog mob ntshav qab zib ketoacidosis, mob hnyav, phais loj thiab hypoglycemia. Glibenclamide belongs rau sulfonylurea hypoglycemic tshuaj, thiab nws cov contraindications yog mob ntshav qab zib ketoacidosis, kub hnyiab, mob, phais loj thiab hypoglycemia.
Qhov twg zoo dua, Glimepiride lossis Glibenclamide?
1. Glibenclamide yog thawj tiam ntawm sulfonylurea hypoglycemic agents, thiab glimepiride yog thawj tiam ntawm sulfonylurea hypoglycemic agents;
2. Cov teebmeem hypoglycemic ntawm glimepiride thiab glibenclamide sib txawv. Glimepiride muaj cov yam ntxwv ntawm kev ua haujlwm ntev, tswj cov insulin secretion thiab tsis tshua muaj kev pheej hmoo ntawm hypoglycemia, thaum glibenclamide muaj cov nyhuv luv luv thiab muaj kev pheej hmoo siab ntawm hypoglycemia, yog li nws tsis tshua siv tam sim no.
Dab tsi yog kev ceev faj ntawm Glibenclamide?
1. Ob peb tus neeg mob muaj qhov tsis xis nyob hauv plab, ua npaws, ua xua ntawm daim tawv nqaij thiab cov tsos mob ntawm hypoglycemia, thiab yuav tsum tau txo lossis nres.
2. Cov neeg mob lub siab ua haujlwm tsis zoo yuav tsum tau ua tib zoo sau thiab txheeb xyuas los ntawm kev kawm kho mob network.
3. Kev mob hnyav decompensated acidosis, mob ntshav qab zib coma, lub raum tsis txaus, ntshav qab zib ketosis thiab cov hluas, menyuam yaus thiab cov poj niam cev xeeb tub tsis haum rau kev siv.
Cov tshuaj no muaj cov nyhuv diuretic me ntsis.
5. Insulin-dependent diabetes mellitus nrog mob hnyav, cev xeeb tub thiab lub siab thiab lub raum tsis ua haujlwm raug txwv.
Yuav ua li cas thiab qhov twg yuav Glibenclamide Powder wholesale?
Koj tuaj yeem tso siab rau peb qhov kev txiav txim vim tias peb muaj cov ntaub ntawv zoo ntawm kev muag tshuaj qhia kev cai lij choj.
Peb ua qhov kev kuaj xyuas ywj pheej ntawm txhua yam khoom thiab tom qab ntawd muag rau peb cov neeg siv khoom hwm.
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:allen@faithfulbio.comTam sim no.
Muaj ntau txoj kev xa khoom rau koj xaiv
|
Tsheb thauj mus los |
Shipping txoj kev |
Cargo hnyav xav tau |
Qhov zoo |
|
3-7 hnub |
DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, |
Haum rau qis dua 50kg. |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, |
|
7-15 hnub |
Los ntawm Cua |
Haum rau ntau tshaj 50kg. |
|
|
15-60 hnub |
Los ntawm Hiav Txwv |
Haum rau ntau tshaj 500kg. |
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:allen@faithfulbio.comTam sim no.
Tsis lees paub: Cov ntawv luam tawm ntawm lub xaib no yog siv los txhawb kev sib pauv kev kawm thiab kev kawm, thiab tsis txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm nws cov ntsiab lus. Thov lim kom zoo. Yog tias koj ntseeg tias tsab xov xwm no ua txhaum, thov hu rau tus thawj tswj hwm. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv cov ntaub ntawv thiab cov kev pabcuam hauv lub vev xaib no.
Nco tseg: Cov tshuaj no yuav tsum tau siv rau kev tshawb fawb nkaus xwb. Cov lus thov no tsis tau raug soj ntsuam los ntawm Food and Drug Administration. Thov nrog koj tus kws kho mob tham thiab kawm txog cov kev tshawb fawb muaj ua ntej siv lawv. Cov khoom no tsis yog tsim los kuaj xyuas, kho, kho, lossis tiv thaiv txhua yam kab mob.
Cim npe nrov: glibenclamide hmoov cas 10238-21-8, Suav teb, lwm tus neeg, manufacturers, hoobkas, customized, lag luam wholesale, yuav, nqe, tej, ntshiab, tsim, luv nqi, muag, Tshuag, dawb qauv, raw hmoov, raw khoom, ua nyob rau hauv Tuam Tshoj