Bimatoprost hmoovyog ib qho tshuaj prostaglandin, uas yog thawj zaug siv los kho cov kab mob ophthalmic xws li glaucoma. Cov tshuaj lub npe yog Lumigan. Txawm li cas los xij, thaum kho, tus neeg mob tau pom tias txoj kab uas hla, qhov ntev, thiab qhov ntom ntawm nws cov plaub muag tau nce ntau. Tom qab ntawd, bimatoprost tau siv rau hauv kev sim tshuaj ntawm cov plaub muag kev zoo nkauj, thiab nws cov txiaj ntsig zoo ntawm cov plaub muag tuab thiab cov plaub muag ncaj qha coj mus rau lub hom phiaj ntawm Lattice los ntawm Ai Jian, lub tuam txhab tsim khoom ntawm Lumen, uas tau pom zoo los ntawm FDA thaum Lub Kaum Ob Hlis 2008 thiab los ua ib qho khoom lag luam rau blackening thiab thickening plaub muag.
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| Bimatoprost hmoov | Bimatoprost Tshuaj formula |
Khoom siv
Bimatoprost hmoovyog ib tug hluavtaws derivative ntawm Prostamide F2, uas muaj peev xwm xaiv simulate qhov kev txiav txim ntawm Prostamide ua nyob rau hauv vivo, nce tus nqi ntawm aqueous lom zem ntau lawm thiab txo cov tsis kam ntawm aqueous lom zem outflow. Bimatoprost tuaj yeem txo qhov siab ntawm lub cev (IOP) los ntawm kev ua kom cov dej ntws tawm ntawm cov dej lom zem los ntawm trabecular meshwork channel thiab Uveoscleral channel. Bimatoprost tau suav tias yog cov tshuaj tiv thaiv kab mob glaucoma hauv zos tam sim no thiab tsim nyog rau kev kho cov neeg mob uas muaj qhov qhib-angle glaucoma (POAG) lossis ocular hypertension (OHT) uas tsis muaj txiaj ntsig los ntawm lwm cov tshuaj txo qis hauv intraocular.
Cov tshuaj nquag rau glaucoma:
1, prostaglandin derivatives xws li latanoprost (Xalatan), piv nrogBimatoprost hmoov(Lumigan) thiab Travatan, nce qhov ntws tawm ntawm Uveoscleral hauv dej lom zem. Misoprostol kuj nce trabecular outflow.
2. Cov neeg ua hauj lwm hauv zos -adrenergic xws li thiamethoxam, levobunolol (Betagan), thiab labetalol tuaj yeem txo cov receptor antagonists hauv aqueous lom zem ntawm lub cev ciliary.
3. Cov txheej txheem dual ntawm alpha2-adrenoceptor agonists xws li Alphagan tuaj yeem txo cov dej ntau lawm thiab ua rau cov kab mob sib kis.
4. Ib rooj plaub ntawm deselection, zoo li epinephrine thiab dipivefrin (Propine), ua rau muaj kev tawm ntawm aqueous lom zem los ntawm trabecular meshwork, uas tej zaum yuav tshwm sim los ntawm kev ua ntawm ib tug 2- receptor agonist.
5. parasympathomimetics, xws li cov leeg ciliary contraction Roca, tuaj yeem ua kom nruj rau trabeculae thiab tso cai rau kom nce cov dej tawm ntawm kev lom zem. Ecothiopate yog siv rau mob glaucoma.
6, xws li Trusopt thiab Azopt, uas tuaj yeem txo qhov tso tawm ntawm carbonic anhydrase inhibitors los ntawm inhibiting carbonic anhydrase hauv lub cev ciliary.
7. Physostigmine kuj tseem siv los kho mob glaucoma thiab ncua lub plab khoob.
Khoom Specification
Yam khoom | Specifications | Cov txiaj ntsig |
Qhov tshwm sim | Dawb hmoov | Dawb hmoov |
Kev txheeb xyuas | HPLC tuav lub sij hawm ntawm tus qauv ua raws li cov qauv paub | Ua raws |
Kev sib hloov tshwj xeeb | [a]D20:+33.0 degree ~+37.0 degree (C=1.0,CH3CN) | {0}}.0 degree |
Dej | Tsawg dua lossis sib npaug rau 1.0% | 0.31% |
Cov khoom muaj feem xyuam | 15R-Bimatoprost: Tsawg dua lossis sib npaug rau 0.30% | Tsis pom |
Residual kuab tshuaj | Ter-Butylmethyl ether: Tsawg dua lossis sib npaug li 5000ppm | Tsis pom |
Purity | Ntau dua lossis sib npaug li 99.5% | 99.82% |
Tsis lees paub: tshwj tsis yog tias tau teev tseg, tsab xov xwm kev paub luam tawm los ntawm lub vev xaib no los ntawm Is Taws Nem thiab feem ntau yog siv los txhawb kev sib pauv kev kawm thiab kev kawm. Nws tsis txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm nws cov ntsiab lus. Thov ua tib zoo tshuaj xyuas nws. Yog tias koj xav tias muaj kev ua txhaum cai hauv tsab xov xwm no, thov hu rau tus thawj tswj hwm. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv cov ntaub ntawv thiab kev pabcuam ntawm lub vev xaib no.
Nco tseg: Tag nrho cov tebchaw muaj kev pheej hmoo. Thov nrog koj tus kws qhia ntawv, kws kho mob, lossis lwm tus kws tshawb fawb ua ntej siv. Cov khoom no tsis yog siv los kuaj xyuas, tiv thaiv lossis kho cov kab mob, tab sis tsuas yog siv rau kev tshawb fawb tshawb fawb. Lub tuam txhab tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv tsis raug.
Yog tias koj xav tau kev pab, thov hu rau peb
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Tsheb thauj mus los | Shipping txoj kev | Cargo hnyav xav tau | Qhov zoo |
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Cim npe nrov: bimatoprost hmoov cas 155206-00-1, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, ntshiab, tsim, kev muag khoom