Heparin Sodium hmoov CAS 9041-08-1

Heparin sodiumyog ib qho tshuaj tua kab mob, yog ib hom mucosaccharide, yog muab rho tawm los ntawm cov hnyuv mucosa ntawm npua, nyuj, yaj sodium ntsev glucosamine sulfate, nyob rau hauv tib neeg lub cev yog secreted los ntawm mast hlwb thiab ib txwm muaj nyob rau hauv cov ntshav. Heparin sodium tuaj yeem tiv thaiv platelet aggregation thiab kev puas tsuaj, inhibit kev hloov pauv ntawm fibrinogen rau hauv fibrin monomer, inhibit qhov tsim ntawm thrombin thiab tiv thaiv cov thrombin uas twb muaj lawm, tiv thaiv kev hloov pauv ntawm prothrombin rau hauv thrombin thiab anti-thrombin. Heparin sodium tuaj yeem ncua lossis tiv thaiv cov ntshav txhaws hauv thiab tawm ntawm lub cev.

Nws cov txheej txheem ntawm kev ua haujlwm yog qhov nyuaj heev, thiab nws muaj feem cuam tshuam rau ntau qhov txuas hauv cov txheej txheem ntawm coagulation. Nws cov teebmeem yog raws li hauv qab no: inhibit qhov tsim thiab kev ua ntawm thromboplastin, yog li tiv thaiv prothrombin los ntawm kev ua thrombin;

Nyob rau hauv ntau dua, nws muaj peev xwm inhibit thrombin thiab lwm yam coagulation yam thiab tiv thaiv fibrinogen los ua fibrin; Nws tuaj yeem tiv thaiv platelet agglutination thiab kev puas tsuaj. Tsis tas li ntawd, cov nyhuv anticoagulant ntawm heparin sodium tseem muaj feem cuam tshuam rau qhov tsis zoo sulfate hauv nws cov molecules, thiab cov khoom zoo alkaline xws li protamine lossis toluidine xiav tuaj yeem ua rau nws cov nqi tsis zoo, yog li nws tuaj yeem cuam tshuam nws cov nyhuv anticoagulant. Vim tias heparin tuaj yeem qhib thiab tso tawm lipoprotein esterase hauv lub cev, yog li ntawd chylomicron triglyceride thiab low-density lipoprotein hydrolysis, yog li nws kuj muaj txiaj ntsig los txo cov ntshav lipid. Heparin sodium tuaj yeem siv los kho cov kab mob thromboembolic, tshaj tawm cov kab mob hauv lub cev (DIC). Nyob rau hauv xyoo tas los no, nws tau pom tias heparin muaj cov nyhuv tshem tawm cov ntshav lipid.