Khoom Taw Qhia
Methimazole hmoovyog ib qho tshuaj imidazole antithyroid, tsis yog tshuaj hormone. Cov khoom lag luam hauv khw feem ntau hu ua methimazole, methimazole, thiab methithiazole. Nws yog tsuas yog siv los kho hyperthyroidism. Nws inhibits peroxidase system thiab cuam tshuam cov synthesis ntawm thyroxine (T4) thiab triiodothyronine (T3). Cov kev sim tsiaj tau pom tias nws tuaj yeem cuam tshuam cov synthesis ntawm cov tshuaj tiv thaiv kab mob los ntawm B lymphocytes, txo cov thyroid-stimulating antibodies hauv cov ntshav ncig, thiab rov ua haujlwm li qub ntawm T cells. Nws yog haum rau hyperthyroidism tshwm sim los ntawm ntau yam.
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| Methimazole hmoov Daim duab | Methimazole hmoov MF |
Khoom siv
Methimazole hmoovyog siv rau kev kho mob ntawm hyperthyroidism. Nws yog qhov tsim nyog rau cov mob me thiab cov uas tsis tsim nyog rau kev phais lossis kev kho mob iodine, xws li cov menyuam yaus, cov tub ntxhais hluas thiab cov neeg uas tau rov qab los tom qab kev phais thiab tsis haum rau kev kho mob radioactive iodine. Nws kuj tseem siv tau los ua kev kho mob ntxiv thaum lub sij hawm kho hluav taws xob iodine.
Txog kev sib txuas ntawm methimazole: Nws yog npaj los ntawm cov tshuaj tiv thaiv ntawm aminoacetaldehyde diethyl acetal nrog methyl isothiocyanate. Nws tuaj yeem npaj tau los ntawm cov tshuaj tiv thaiv ntawm thiocyanic acid nrog N-substituted aminoacetal. Nws tuaj yeem npaj tau los ntawm cov tshuaj tiv thaiv ntawm thiocyanic acid nrog N-substituted aminoacetal. Base hydrolysis ntawm imidazole carboxylate tau pom tias yog ib txoj hauv kev zoo rau kev sib txuas ntawm cov tshuaj antithyroid methimazole.
Ethyl 3-methyl-2-thioxo-2, 3-dihydro-1H-imidazole-1-carboxylate tau tsim los ua ib qho tseem ceeb hauv cov tshuaj tiv thaiv ntawm { {7}}methyl-1H-imidazole nrog ethyl chloroformate thiab sulfur. Compound 12 undergoes hydrolysis nyob rau hauv ob kauj ruam nyob rau hauv lub xub ntiag ntawm lub hauv paus muab methimazole nrog ib tug tag nrho yield ntawm 78%. Cov txheej txheem tau kawm los ntawm Lub Tswv Yim Zoo los ntawm Tsim (QbD) lub tswv yim thiab pom tias muaj zog.
Khoom Specification
| Cov khoom | Cov qauv | Cov txiaj ntsig |
| Kev tshuaj xyuas lub cev | ||
| Kev piav qhia | Dawb rau me ntsis cream los yog lub teeb daj crystalline hmoov | Ua raws |
| Assay | Synephrine hcl 98% (HPLC) | 98.12% |
| Mesh Loj | 100% dhau 80 mesh | Ua raws |
| Tshauv | Tsawg dua lossis sib npaug rau 5.0% | 3.85% |
| Poob rau ziab | Tsawg dua lossis sib npaug rau 5.0% | 3.45% |
| Tshuaj ntsuam xyuas | ||
| Hnyav Hlau | Tsawg dua lossis sib npaug li 10.0 mg/kg | Ua raws |
| Pb | Tsawg dua lossis sib npaug rau 2.0 mg/kg | Ua raws |
| Raws li | Tsawg dua los yog sib npaug rau 1.0 mg/kg | Ua raws |
| Hg | Tsawg dua los yog sib npaug rau 1.0 mg/kg | Ua raws |
| Microbiological Analysis | ||
| Cov tshuaj tua kab residue | Tsis zoo | Tsis zoo |
| Tag nrho cov phaj suav | Tsawg dua lossis sib npaug li 1000cfu / g | Ua raws |
| Yeast & Pwm | Tsawg dua lossis sib npaug li 100cfu / g | Ua raws |
| E.coil | Tsis zoo | Tsis zoo |
| Salmonella | Tsis zoo | Tsis zoo |
| Xaus | Ua raws li tus qauv kev lag luam | |
Yuav Ua Li Cas Kom Tau Txais Cov QauvMethimazole hmoov?
Txais tos xa ib qho kev nug rausunny@faithfulbio.comtxhua lub sijhawm rau tus qauv dawb yog tias koj xav tau APIMethimazole hmoov.
Qhov zoo tshaj plaws Methimazole hmoov Chaw tsim tshuaj paus thiab tsum
Faithfulbio muaj kev paub dhau los hauv kev xa tawm cov ntaub ntawv raw thiab tau tsim kev sib raug zoo thiab kev koom tes ntev nrog peb cov neeg siv khoom. Peb ib txwm muab cov khoom zoo thiab kev pabcuam ua ntej. Yog tias koj muaj cov khoom siv raw khoom xav tau, thov hu rau peb. Peb tuaj yeem lees paub qhov kev txiav txim nrog koj raws li koj qhov yuav khoom ntau. Peb kuj txhawb peb txoj kev koom tes thawj zaug pib los ntawm cov qauv. Tsis tas li ntawd, peb txoj kev thauj mus los sai thiab nyab xeeb kuj ua rau koj tshem tawm cov teeb meem ntawm kev lis kev cai.
Peb muaj kev ntseeg siab ntawm peb cov khoom zoo, tab sis yog tias muaj teeb meem tom qab muag, peb yuav teb sai li sai tau thiab daws lawv nrog koj txoj hauv kev zoo tshaj plaws.
Vim Li Cas Xaiv FaithfulbioMethimazole hmoov?
Faithfulbio tshwj xeeb hauvMethimazole hmoovrau ntau xyoo, peb muab cov khoom ntawm tus nqi sib tw, thiab peb cov khoom yog qhov zoo tshaj plaws, vim tias peb nruj heev hauv cov khoom tsim thiab kev sim, thiab muaj kev ua tiav thiab paub tab. Tsis tas li ntawd, peb cov neeg ua haujlwm Cov lus hais rau cov khoom muaj kev sib tw heev.
Muaj ntau txoj kev xa khoom rau koj xaiv
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Tsheb thauj mus los |
Shipping txoj kev |
Cargo hnyav xav tau |
Qhov zoo |
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3-7 hnub |
DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, |
Haum rau qis dua 50kg. |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, |
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7-15 hnub |
Los ntawm Cua |
Haum rau ntau tshaj 50kg. |
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15-60 hnub |
Los ntawm Hiav Txwv |
Haum rau ntau tshaj 500kg. |
ua siab zoo ceeb toom:SivMethimazole hmoovrau kev tshawb fawb nkaus xwb. Txhua lub tebchaw muaj kev pheej hmoo. Thov nrog koj tus kws kho mob tham thiab kawm txog cov kev tshawb fawb muaj ua ntej siv. Tsis tas li ntawd, cov lus piav qhia saum toj no ntawm qhov sib xyaw yog los ntawm cov ntaub ntawv online. Yog tias muaj kev ua txhaum cai, thov hu rau peb kom tshem tawm.
Yuav Methimazole hmoov nyob qhov twg?
Cia li xa email rausunny@faithfulbio.com, lossis xa koj qhov yuav tsum tau ua hauv daim ntawv hauv qab, peb muaj kev pabcuam txhua lub sijhawm!
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