Pantoprazole Sodium yog dab tsi?
Pantoprazole Sodium yog ib qho H +, K+-ATPase inhibitor, uas tuaj yeem cuam tshuam cov kua qaub hauv plab uas txhawb nqa los ntawm histamine, gastrin, acetylcholine thiab lwm yam. Nws yog siv los kho cov kab mob ntsig txog gastric acid secretion disorder, nrog rau qhov zoo ntawm kev kho tus nqi siab, pib sai thiab tsis tshua muaj tshwm sim.
Pantoprazole soda hmoovyog cov hmoov dawb mus rau dawb dawb.
Pantoprazole sodium yog ib qho ntawm ntau hom proton twj tso kua mis inhibitors (PPI) hauv khw tam sim no. Raws li cov ntaub ntawv qhia, bioavailability ntawm pantoprazole yog 7 npaug ntau dua li ntawm omeprazole, thiab nws cov kev xaiv rau parietal hlwb yog qhov tshwj xeeb.
| Khoom npe | Pantoprazole Sodium |
| CAS | 138786-67-1 |
| Cov mis mos molecular | C16H14F2N3NaO4S |
| Molecular hnyav | 405.35 |
| EINECS Number | 604-093-4 |
| Kev cia khoom | Inert cua, Khaws hauv lub freezer, hauv qab -20 degree |
| Melting point | 199-202 degree |
| Solubility | Soluble hauv DMSO (me ntsis), methanol (me ntsis, ultrasonic kho) thiab dej (me ntsis) |
| Qhov tshwm sim | Dawb mus rau dawb hmoov |
| Boiling point | 586.9 degree ntawm 760 mmHg |
| Kev ruaj ntseg | hygroscopicity |
Yuav ua li cas yog lub pharmacological mechanism ntawm Pantoprazole Sodium?
Pantoprazole Sodium yog proton twj tso kua mis inhibitor rau gastric parietal hlwb. Nws yog ib qho ruaj khov nyob rau hauv nruab nrab thiab tsis muaj zog acidic tej yam kev mob thiab sai activated nyob rau hauv muaj zog acidic tej yam kev mob. Nws cov yam ntxwv ua kom pH-raws li ua rau nws xaiv ntau dua rau H + thiab K+-ATPase. Pantoprazole Sodium tuaj yeem tshwj xeeb inhibit H + thiab K+-ATPase ntawm secretory microtubules thiab tubular vesicles nyob rau hauv cytoplasm ntawm apical membrane ntawm parietal hlwb, ua rau irreversible inhibition ntawm lub enzyme, yog li zoo inhibiting gastric acid secretion. Txij li H + thiab K+-ATPase yog cov txheej txheem kawg ntawm cov kua qaub tso rau hauv parietal hlwb, cov khoom no muaj peev xwm tiv thaiv cov kua qaub.
Pantoprazole Sodium hmoovtuaj yeem tsis tsuas yog tsis muaj kev sib tw ua rau lub plab acid secretion los ntawm gastrin, histamine, thiab choline, tab sis kuj inhibit qee qhov basal gastric acid secretion uas tsis cuam tshuam los ntawm choline lossis H2 receptor blockers. Thaum siv nrog lwm cov khoom, EUPANTOL muaj qhov zoo ntawm cov tshuaj me me. PANTECTA yog metabolized los ntawm I system ntawm cytochrome P450 enzyme system hauv hepatocytes, thiab tseem tuaj yeem metabolized los ntawm II system. Thaum siv nrog lwm cov tshuaj uas tau metabolized los ntawm P450 enzyme system, txoj kev metabolic ntawm Pantoprazole Sodium tuaj yeem ua tiav los ntawm II enzyme system, uas ua rau nws tsis tshua muaj kev sib tw ntawm cov tshuaj-metabolizing enzyme systems thiab txo cov tshuaj sib cuam tshuam hauv cov tshuaj. lub cev. Nws tsis muaj mutagenic, carcinogenic, lossis teratogenic cuam tshuam.
Khoom Specification
| Yam khoom | Specification | Cov txiaj ntsig |
| Qhov tshwm sim | Ntawm-dawb rau Dawb hmoov | Ua raws |
| Kev sib hloov los ntawm | -0.4 degree rau +0.4 degree | Ua raws |
| Alkalinity pH tus nqi | 9.5~11.0 | 9.6~10.9 |
| Muaj feem xyuam | Tus kheej impurity:NMT0.2% | 0.06% |
| Tag nrho cov impurities: NMT0.5% | 0.13% | |
| Moisture | 4.0%~6.0% | 5.0% |
| Heavy meta | NMT 20 ppm | NMT 20 ppm |
| Assay | NLT 98. 0% | 99.35% |
| Concusion: | Ua raws li kev lag luam specification. | |
Pantoprazole Sodium hloov mus rau dab tsi?
1. Peptic ulcer los ntshav.
2. Mob plab hnyuv raug mob los ntawm cov tshuaj uas tsis yog-steroidal anti-inflammatory thiab tshwm sim ntawm ulcer los ntshav nyob rau hauv kev ntxhov siab;
3. Tiv thaiv gastric acid reflux nyuaj nrog aspiration pneumonia tom qab siv tshuaj loog lossis kev phais loj thiab hauv cov neeg mob uas tsis nco qab debilitating.
4. Cov tshuaj tiv thaiv kab mob thiab cov tshuaj tiv thaiv kab mob yog siv los kho cov mob plab hnyuv loj xws li gastric thiab duodenal ulcer, mob plab mucosal lesion ntawm gastric ulcer thiab compound gastric ulcer.
HTML5 atlas ntawm Pantoprazole Sodium
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Dab tsi yog qhov zoo ntawm Pantoprazole Sodium?
1. Qhov chaw ua haujlwm raug: Pantoprazole Sodium tsuas yog khi rau cov khoom nquag 5 thiab 6 ntawm lub twj tso kua mis proton nrog qhov tshwj xeeb, thaum omeprazole kuj khi rau qhov tsis muaj zog 7 thiab 8, thiab lansoprazole kuj khi rau qhov tsis muaj zog 7, 8 thiab 3. tawg tawg.
2. Kev sib cuam tshuam ntawm cov tshuaj tsawg: Pantoprazole Sodium tsis cuam tshuam rau kev ua haujlwm ntawm P450 enzyme system ntawm daim siab hlwb.
3. Tsis muaj qhov sib txawv tseem ceeb hauv kev kho tus nqi ntawm duodenal ulcer thiab gastric ulcer kho nrog Pantoprazole Sodium thiab omeprazole, thiab Pantoprazole Sodium zoo dua zam.
4. Pantoprazole Sodium hmoovtsis muaj qhov sib txawv ntawm kev ua tau zoo nrog omeprazole hauv kev kho mob plab hnyuv los ntshav los ntawm kev mob plab hnyuv los ntawm ntau yam laj thawj, thiab muaj kev phiv tsis zoo. Nws yog ib qho ntawm cov tshuaj muaj kev nyab xeeb thiab txhim khu kev qha rau kev kho mob plab hnyuv los ntshav.
Kev piav qhia ntawm kev nqus sab nraud ntawm Pantoprazole sodium:
Pantoprazole sodium muaj cov qauv tshuaj sulfenylbenzimidazole, thiab nws txoj kev ruaj ntseg yog yooj yim cuam tshuam los ntawm ntau yam xws li lub teeb, hnyav hlau ions, oxidizing thiab txo cov khoom. Tshwj xeeb tshaj yog nyob rau hauv acidic tej yam kev mob, cov qauv tshuaj ntawm Pantoprazole sodium tuaj yeem hloov pauv kev puas tsuaj, ua rau muaj xim tsis zoo thiab polymerization. Yog li ntawd, Pantoprazole sodium yog tsis ruaj tsis khov nyob rau hauv acidic diluents, uas yuav yooj yim ua rau wavelength hloov thaum lub sij hawm ultraviolet identification. Siv dej los ua cov kuab tshuaj: ① Siv cov dej lim dej ua cov kuab tshuaj: Kev nqus ultraviolet tshwm sim yam tsis muaj kev hloov pauv acidity (pH{{0}}}.47) tsis ua raws li tus qauv xav tau. Tom qab hloov acidity (pH{2}}.85), cov txiaj ntsig ultraviolet nqus tau raws li tus qauv yuav tsum tau ua, thiab nws tsis tsim nyog siv cov dej lim dej ua cov kuab tshuaj. ② Siv cov dej tsis huv rau kev txhaj tshuaj raws li cov kuab tshuaj: (pH=6.83) Cov txiaj ntsig ultraviolet nqus tau raws li tus qauv yuav tsum tau ua, tab sis txij li qhov tsim nyog acidity ntau ntawm cov dej tsis muaj menyuam rau kev txhaj tshuaj yog pH5.0-7.0 . Yog li ntawd, nws tsis tsim nyog siv cov dej tsis huv rau kev txhaj tshuaj raws li qhov hnyav. ③ Siv anhydrous ethanol ua hnyav: Xa mus rau tus qauv kev txheeb xyuas qhov zoo ntawm cov khoom siv tshuaj, anhydrous ethanol tau siv los ua cov kuab tshuaj, thiab tau txais txiaj ntsig zoo. .
Hauv cov ntsiab lus, lub wavelength hloov hauv kev txheeb xyuas ultraviolet ntawm Pantoprazole sodium yog ze ze rau pH ntawm diluent. Kev kuaj xyuas ultraviolet nqus tau siv cov dej tsis huv rau kev txhaj tshuaj thiab anhydrous ethanol li diluents tau ua tiav cov txiaj ntsig zoo. Xav tias pH nyob rau hauv tus qauv zoo ntawm cov dej tsis muaj menyuam rau kev txhaj tshuaj yog 5-7, nws yog ib qho kev daws zoo dua los siv cov tshuaj anhydrous ethanol raws li cov tshuaj diluent thaum lub sij hawm kuaj xyuas ultraviolet, uas yog ib txoj hauv kev zoo tshaj plaws rau kev txheeb xyuas ultraviolet ntawm Pantoprazole sodium rau kev txhaj tshuaj.
Dab tsi yog qhov txawv ntawm Pantoprazole sodium thiab omeprazole?
Pantoprazole sodium hmoovthiab omeprazole hmoov yog ob qho tib si proton twj tso kua mis inhibitors uas tuaj yeem inhibit gastric acid secretion.
Lawv qhov sib txawv tseem ceeb yog:
1. Cov qauv tshuaj sib txawv thiab cov tshuaj tiv thaiv acid. Omeprazole yog thawj tiam proton twj tso kua mis inhibitor. Pantoprazole sodium yog ib qho kev hloov kho cov qauv ntawm omeprazole, uas muaj cov kua qaub zoo dua thiab siv sijhawm ntev dua.
2. Kev ruaj ntseg sib txawv. Nyob rau hauv acidic tej yam kev mob, Pantoprazole sodium yog ruaj khov dua omeprazole.
3. Sib txawv tshuaj sib txawv. Omeprazole muaj cov tshuaj sib cuam tshuam ntau dua, thaum Pantoprazole sodium muaj qhov cuam tshuam tsis zoo rau lub siab enzymes, muaj kev cuam tshuam tshuaj tsawg dua, thiab muaj kev nyab xeeb dua.
Yuav ua li cas thiab qhov twg yuav Pantoprazole Sodium Powder lag luam wholesale?
Koj tuaj yeem tso siab rau peb qhov kev txiav txim vim tias peb muaj cov ntaub ntawv zoo ntawm kev muag tshuaj raws cai.
Peb ua qhov kev kuaj xyuas ywj pheej ntawm txhua yam khoom thiab tom qab ntawd muag rau peb cov neeg siv khoom hwm.
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:allen@faithfulbio.comTam sim no.
Muaj ntau txoj kev xa khoom rau koj xaiv
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Tsheb thauj mus los |
Shipping txoj kev |
Cargo hnyav xav tau |
Qhov zoo |
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3-7 hnub |
DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, |
Haum rau qis dua 50kg. |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, |
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7-15 hnub |
Los ntawm Cua |
Haum rau ntau tshaj 50kg. |
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15-60 hnub |
Los ntawm Hiav Txwv |
Haum rau ntau tshaj 500kg. |
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:allen@faithfulbio.comTam sim no.
Tsis lees paub: Cov ntawv luam tawm ntawm lub xaib no yog siv los txhawb kev sib pauv kev kawm thiab kev kawm, thiab tsis txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm nws cov ntsiab lus. Thov lim kom zoo. Yog tias koj ntseeg tias tsab xov xwm no ua txhaum, thov hu rau tus thawj tswj hwm. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv cov ntaub ntawv thiab cov kev pabcuam hauv lub vev xaib no.
Nco tseg: Cov tshuaj no yuav tsum tau siv rau kev tshawb fawb nkaus xwb. Cov lus thov no tsis tau raug soj ntsuam los ntawm Food and Drug Administration. Thov nrog koj tus kws kho mob tham thiab kawm txog cov kev tshawb fawb muaj ua ntej siv lawv. Cov khoom no tsis yog tsim los kuaj xyuas, kho, kho, lossis tiv thaiv txhua yam kab mob.
Cim npe nrov: pantoprazole sodium hmoov cas 138786-67-1, Suav teb, lwm tus neeg, manufacturers, hoobkas, customized, lag luam wholesale, yuav, nqe, tej, ntshiab, tsim, luv nqi, kev muag, Tshuag, dawb qauv, raw hmoov, raw khoom, ua hauv Suav teb