Calcifediol monohydrate CAS 63283-36-3

Calcifediol MonohydrateTau siv nyob rau hauv qee cov kev tshawb fawb txhawm rau txhim kho cov vitamin d xwm txheej. Qhia rau lawv cov kev siv suav nrog Vitamin D tsis txaus ntseeg (vitamalcemia, hypocalcemia thiab, muaj calcium, nrog cov tshuaj calstealcemia, hypocalcemia thiab, muaj calcium, hauv cov kab mob hypium lossis cov txha corteoporosis.

tuaj yeem kho cov hyperarparathyroidism hauv cov neeg mob muaj kab mob raum

Cov khoom

Cov lus qhia

Qho kawg

Kev tshwm sim

Ntuas

Ntuas

Tus txheeb ze khaws cia: Nrog siv rau Calcifediol (cia sij hawm =}} Hais txog 11 min)

Impurity A =} Hais txog 1.6 (tsawg dua los yog sib luag rau 0.5%),

Impurity b =} txog li 1.1 (tsawg dua lossis sib npaug rau 0.5%)

Impurity c =} txog1.2 (tsawg dua lossis sib npaug nrog 0.5%)

Impurity d =} txog 0.85 (tsawg dua los yog sib luag rau 0.5%)

Ib leeg tsis tau lees paub (tsawg dua los yog sib luag rau 0.1% Max)

Tag nrho cov impurities (tsawg dua los yog sib npaug rau 1.0%)

Tsis pom

0.03%

Tsis pom

0.04%

Tsis pom

0.07%

Calcifediol Monohydrate tau hloov pauv hauv lub raum los ntawm 25-hydroxyvitamin d3-1- alpha) -hdroxylase rau calcitriol, qhov nquag ntawm vitamin d3. Calcitriol khi rau intracellular receptors uas ces muaj nuj nqi raws li cov khoom xa khoom los hloov cov noob. Zoo li cov khoom siv stereptors rau lwm cov tshuaj steroid thiab cov qog ua qog thiab cov vitamin D Receptor muaj cov txiaj ntsig hormones thiab DNA. Lub vitamin d receptor cov ntawv ib txoj kev nyuaj nrog lwm cov recacellular receptor, tus retinoid-x receptor, thiab tias heterodimer yog dab tsi khi rau DNA. Feem ntau tau kawm, cov nyhuv yog los qhib kev sau ntawv, tab sis cov xwm txheej tseem paub nyob rau hauv uas vitamin d suppresses sau. Calcitriol tsub kom cov ntshav qab zib cov tshuaj calcium ntau tshaj plaws los ntawm: Nce Gi yuav rov muab dua, thiab nce siab dua cov roj ntsha tub siab dua ntawm cov calcium. Coditriol tshwm sim txhawb kev nqus cov tshuaj tsw qab los ntawm kev khi rau Vitamin D Receposal Cytoplasm ntawm txoj hnyuv. Tom qab, cov calcium yog nqus tau los ntawm kev tsim cov calcium-khi protein.