Fmoc-L-Proline yog dab tsi?
Headquartered nyob rau hauv Xi'an, keeb kwm keeb kwm ntawm lub ancient Silk Road, Xi'an Faithful BioTech Co., Ltd. siv tag nrho kom zoo dua ntawm lub nroog lub robust logistics thiab tshuaj muaj peev xwm los txhim kho mus rau hauv ib tug zoo zoo tshuaj muab kev pab rau cov neeg siv khoom thoob ntiaj teb.Fmoc-L-Prolineyog ib qho uas nquag siv chiral amino acid monomer hauv cov khoom siv -theem peptide synthesis, nrog rau cov mis molecular C₂₀H₁₉NO₄. Nws zoo nkaus li cov hmoov dawb crystalline, yooj yim soluble hauv cov organic reagents tab sis sparingly soluble hauv dej. Cov molecule muaj Fmoc amino tiv thaiv pab pawg, ua rau nws sib xws nrog cov txheej txheem tseem ceeb Fmoc synthesis. Cov qauv cyclic pyrrolidine tshwj xeeb ntawm proline tuaj yeem hloov kho qhov sib txawv ntawm peptide chains, feem ntau siv los npaj peptide molecules nrog folded lossis cyclic conformations. Cov khoom no boasts siab chromatographic purity thiab tsis tshua muaj chiral impurity cov ntsiab lus, ua rau nws tsim nyog rau kev tshawb fawb daim ntaub ntawv xws li peptide tsev qiv ntawv kev tsim kho, kev tshawb fawb ntawm lom conformation mechanisms, thiab kev npaj ntawm functional peptide fragments. Cov khoom yuav tsum tau muab khaws cia rau hauv qhov txias, tsaus, thiab kaw lub thawv kom tsis txhob ya raws, oxidation, thiab tawg. Thaum lub sij hawm synthesis coupling theem, nws yog feem ntau siv nrog HATU los yog DIC condensing agents kom tiav peptide daim ntawv cog lus linkage, ua nws ib tug tseem ceeb raw khoom nyob rau hauv lub teb ntawm biochemical cov ntaub ntawv tshawb fawb thiab kev loj hlob.
Fmoc-L-Proline Manufacturing Process
Siv L-Proline li raw khoom, Fmoc-Cl organic hnyav tau ntxiv thiab ua rau muaj kev cuam tshuam rau hauv ib puag ncig alkaline aqueous, nrog rau qhov kub thiab txias tswj kom ua tiav cov amino tiv thaiv. Cov sib tov tau tso cai sawv ntsug thiab sib cais rau hauv txheej kom tshem tawm cov theem aqueous, thiab cov theem ntawm cov organic yog ntxuav nrog dej kom tshem tawm ntsev. Tom qab cov concentration, cov kuab tshuaj crystallization tau ntxiv thiab qhov sib tov tau txias kom precipitate cov khoom crude. Cov khoom nyoos tau lim los ntawm recrystallization, lim, qhuav nyob rau hauv qis -kub nqus tsev vacuum, thiab sieved kom tau ib tug dawb hmoov khoom. Tom qab dhau qhov kev xeem purity thiab chirality, cov khoom tau ntim thiab khaws cia.
COA
| Cov khoom kuaj | Specification | Kev Xeem |
| HPLC Purity | Ntau dua lossis sib npaug li 99.5% | 99.72% |
| Kev sib hloov tshwj xeeb []D20 | -30℃~ -34℃(1% hauv DMF) | -32.1 degree |
| Melting Point | 114-120 degree | 117.2 degree |
| Cov ntsiab lus dej | Tsawg dua lossis sib npaug li 0.30% | 0.16% |
| Tib Chiral Impurity | Tsawg dua lossis sib npaug li 0.10% | 0.04% |
| Dawb L-Proline | Tsawg dua lossis sib npaug li 0.10% | <0.02% |
| Heavy Metals (Pb) | Tsawg dua los yog sib npaug li 10 ppm | <5 ppm |
| Residual Solvent | Ua raws li ICH Standard | Ua raws |
| Xaus | Ua raws li kev lag luam specification | |
Nyem email:sales4@faithfulbio.comLos yog WhatsApp:+86 17782784907
Qhov ceev 1.3 ± 0.1 g / cm³
Kub taw tes 548.6 ± 43.0℃ntawm 760 mmHg
Melting point 112-115ºC
Cov mis mos molecular C₂₀H₁₉NO₄
Molecular hnyav 337.369
Flash point 285.6 ± 28.2 degree
Qhov hnyav 337.131409 g / cm³
PSA 66.84000 g/cm³
LogP 3.00 g/cm³
Mechanism of action of Fmoc-L-Proline
Amino pab pawg thaiv thaiv kev tiv thaiv: Fmoc pawg khi rau nitrogen atom ntawm lub nplhaib proline, thaiv cov kev cuam tshuam sab nraud ntawm cov amino pawg thiab tso cai rau kev sib koom ua ke thiab tswj tau hauv peptide bond condensation.
Tswj peptide saw spatial conformation: Lub tsib-ntiv nplhaib cov tswv cuab ntawm proline tsis muaj ib pawg amino dawb; nkag mus rau hauv peptide saw cov ntaub ntawv tig thiab khoov cov qauv, hloov tag nrho spatial morphology ntawm polypeptide.
Kev kho kom haum rau cov khoom sib txuas ua ke: Cov carboxyl terminus tuaj yeem qhib tau nrog cov resins thiab lwm cov amino acids los ntawm cov neeg ua hauj lwm condensation los tsim cov peptide bonds, ua hauj lwm raws li ib tug modular monomer mus cuag cov polypeptide saw.
Cov khoom sib cais yooj yim thiab ua kom huv: Cov pab pawg Fmoc muaj cov qauv uas muaj ntxhiab hydrophobic, txhim kho cov solubility ntawm intermediates nyob rau hauv cov organic theem thiab yooj yim rau kev ntxuav thiab crystallization purification txheej txheem.
vim li cas xaiv peb
Peb ua raws li lub hauv paus ntsiab lus ntawm "tus neeg siv khoom ua ntej, kev ua siab ncaj ua ntej", thiab ib txwm muab cov neeg siv khoom nrog cov khoom zoo thiab muaj txiaj ntsig zoo thiab - cov kev pabcuam zoo. Xaiv kev ncaj ncees. Xaiv lub neej noj qab nyob zoo!
Nrog rau peb cov kev siv zog tas mus li thiab kev pabcuam zoo, peb cia siab tias yuav tsim kom muaj kev koom tes ntev - thiab kev loj hlob zoo nrog cov neeg siv khoom thiab muab sijhawm rau peb. Peb ntseeg tias peb yuav txaus siab rau koj nrog thawj -chav kawm zoo, nyab xeeb thiab xa khoom sai thiab txaus siab tom qab- kev muag khoom.
Peb lub Hoobkas
Pob
Shipping Txoj Kev
| Tsheb thauj mus los | Shipping txoj kev | Cargo hnyav xav tau | Qhov zoo |
| 3-7 hnub | DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, UPS, USPS, FedEx, TNT, EMS |
Haum rau qis dua 50kg. International qhov rooj rau qhov rooj nthuav qhia |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, thiab cov neeg muas zaub nyob rau hauv cov teb chaws Europe thiab America yuav txaus siab rau xa cov khoom ncaj qha los ntawm ob qhov chaw. |
| 7-15 hnub | Los ntawm Cua | Haum rau ntau tshaj 50kg. ceev thiab pheej yig dua rau kev txiav txim loj |
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| 15-60 hnub | Los ntawm Hiav Txwv | Haum rau ntau tshaj 500kg. Kev xa khoom pheej yig tshaj plaws |
FAQ
01. Dab tsi yog tus yam ntxwv ntawm lub proline cyclic qauv?
Fmoc-L-Prolineyog ib tug tsib - koom nrog pyrrolidine nplhaib qauv. Thaum txuas rau peptide saw, nws tuaj yeem ua rau cov saw peptide tsim khoov thiab tig.
02. Dab tsi yog cov ntawv thov tseem ceeb ntawm cov khoom no?
Khoom-theem peptide synthesis, peptide tsev qiv ntawv npaj, thiab bioconformation-txog kev tshawb fawb txog kev sim.
03. Dab tsi condensing agents feem ntau siv rau hauv nws cov synthesis?
HATU, HBTU, thiab DIC tuaj yeem siv ua ke nrog HOAt / HOBt.
Nyem email:Sales4@Faithfulbio.ComLos yog WhatsApp:+86 17782784907
Tsis lees paub:Tag nrho cov khoom lag luam (tsis yog- cov khoom siv kho mob) cov duab raug coj los ua zoo, tab sis vim yog lub zog ntawm lub teeb (lub sijhawm sib txawv, lub teeb tom qab sib txawv), txoj kev tua, cov khoom siv sib txawv thiab lwm yam, tej zaum yuav muaj qee qhov sib txawv ntawm daim duab thiab cov xim tiag tiag, cov xim ntawm cov khoom, thov coj cov nyhuv tiag tiag, xim txawv ntawm cov khoom tsis yog qhov teeb meem zoo.
Nco tseg:Nco ntsoov sab laj nrog tus kws kho mob uas tsim nyog ua ntej noj cov tshuaj tshiab. Cov khoom no tsis yog tsim los kuaj xyuas, kho, kho lossis tiv thaiv txhua yam kab mob.Thaum lub sijhawm yuav khoom, tus neeg yuav khoom thoob ntiaj teb pom zoo xav tias muaj kev pheej hmoo ntawm txhua yam khoom tuaj txog. Peb tsis tuaj yeem hloov cov khoom ploj lossis raug kaw. Ua ntej xa cov khoom, koj yuav tsum paub meej tias koj pom zoo rau cov nqe lus no.Qhov no tsuas yog kev pom zoo koob tshuaj raws li peb tus kheej kev paub thiab cov ntaub ntawv pov thawj. Peb pom zoo kom koj ua koj tus kheej kev tshawb fawb ua ntej siv cov khoom no.
Nqe lus:Cov khoom no tsuas yog siv rau kev tshawb fawb tshawb fawb, thiab qhov tshwm sim ntawm lwm yam kev siv tsis muaj lub luag haujlwm.
Cim npe nrov: fmoc-l-proline cas 71989-31-6, Tuam Tshoj, lwm tus neeg, manufacturers, hoobkas, customized, lag luam wholesale, yuav, nqe, tej, ntshiab, tsim, luv nqi, muag, Tshuag, dawb qauv, raw hmoov, raw khoom, ua nyob rau hauv Suav teb