Pregabalin hmoovFeem ntau yog siv rau kev kho mob ntawm peripheral neuralgia thiab pab kho qee yam kab mob, xws li qaug dab peg. Ib qho yog tus tswj hwm ntawm calcium channels, uas tuaj yeem thaiv cov calcium channel thiab txo qhov tso tawm ntawm cov neurotransmitter no, yog li txo qhov mob neuropathic.
Pregabalin thiab gabapentin muaj tib lub tswv yim ntawm kev ua, feem ntau yog los ntawm inhibition ntawm subunits ntawm voltage-dependent calcium channel nyob rau hauv lub hauv nruab nrab paj hlwb ob δ Protein, txo cov influx ntawm calcium ions, txo qhov tso tawm ntawm excitatory transmitters, thiab restores overexcited neurons rau. ib txwm lub xeev. Tab sis pregabalin thiab ob δ Qhov ua tau zoo ntawm subunit binding yog ntau tshaj 6 npaug ntawm gabapentin. Pregabalin yog ib tug thib ob tiam anticonvulsant, uas khaws cov tshuaj lom neeg ntawm gabapentin thiab txhim kho nws cov yam ntxwv pharmacokinetic. Nws muaj cov yam ntxwv ntawm cov tshuaj pharmacokinetic, uas yog, nrog rau kev siv tshuaj ntau ntxiv, kev ua tau zoo nce ntxiv, kev ua tau zoo tuaj yeem raug ntsuas, thiab nws muaj kev nyab xeeb dua. Pregabalin sai dua hauv kev ua, nqus, bioavailability, thiab kev nyab xeeb dua li gabapentin.
Qhov sib txawv ntawm ob yam khoom hauv kev kho mob vwm
Pregabalin thiab gabapentin yog ob qho tib si tshuaj rau kev kho mob qaug dab peg, uas muaj cov tshuaj tiv thaiv kab mob vwm thiab tshuaj tua kab mob. Qhov kev ua tau zoo ntawm cov tshuaj yuav tsum raug txiav txim raws li tus neeg mob tus mob, lub cev, thiab lwm yam, thiab tsis tuaj yeem muab piv rau. Qee tus neeg mob yuav muaj qee qhov tsis zoo tom qab noj pregabalin thiab gabapentin. Nyob rau hauv cov ntaub ntawv ntawm kev phiv, cov neeg mob yuav tsum tau sib tham nrog cov kws kho mob nyob rau hauv lub sij hawm, thiab cov kws kho mob yuav kho cov kev npaj tshuaj raws li cov neeg mob tus kheej tej yam kev mob.
PregabalinFeem ntau yog siv los kho mob qaug dab peg, post-herpetic neuralgia, thiab lwm yam kab mob. Qee tus neeg mob yuav muaj kiv taub hau, mob taub hau, qaug zog, ataxia, kev hais lus tsis meej, kev xav tsis meej, qhov muag tsis pom kev, myoclonus, thiab lwm yam kev phiv tom qab siv cov tshuaj no. Cov neeg mob hnub nyoog qis dua 12 xyoos yuav tsum tsis txhob siv cov tshuaj no. Cov neeg mob uas muaj lub plawv tsis ua haujlwm, cov neeg laus, thiab cov poj niam cev xeeb tub yuav tsum siv cov tshuaj no nrog ceev faj. Cov poj niam cev xeeb tub yuav tsum tsis txhob pub mis niam thaum lub sijhawm siv tshuaj.
GabapentinFeem ntau yog siv rau kev kho mob ntawm ib nrab qaug dab peg thiab refractory tsis tiav kev qaug dab peg hauv cov chaw kho mob. Cov neeg mob yuav muaj qaug zog, kiv taub hau, dyskinesia, mob taub hau, thiab lwm yam kev phiv tshwm sim thaum kho nrog cov tshuaj no. Cov neeg mob ua xua rau gabapentin thiab cov poj niam lactating yuav tsum tsis txhob siv cov tshuaj no. Cov neeg mob lub raum tsis zoo yuav tsum siv cov tshuaj no nrog ceev faj.
Epilepsytej zaum yuav tshwm sim los ntawm kev puas siab puas ntsws, heredity, trauma, thiab lwm yam. Thaum kho, cov neeg mob yuav tsum sim ua kom zoo siab rau lub siab, zam kev tawm dag zog sab nraud, ua haujlwm tsis tu ncua thiab so, tswj kev noj zaub mov kom zoo, tsis txhob noj cov rog, ntsim, thiab txias, thiab kho cov cwj pwm phem xws li pw tsaug zog, haus dej. cawv, thiab haus luam yeeb. Kev qaug dab peg tsis tu ncua yuav ua rau muaj kev cuam tshuam loj rau kev puas siab puas ntsws ntawm cov neeg mob. Cov neeg mob yuav tsum tsis tu ncua kev sab laj txog kev puas siab puas ntsws, koom tes nrog cov kws kho mob kom kho, noj tshuaj raws sij hawm, thiab sib zog ua kom rov zoo sai.
Yuav ua li cas yog tias koj noj gabapentin ntau dhau lawm?
Gabapentin yog ib qho dav-spectrum antiepileptic tshuaj, uas kuj muaj qee yam kev kho mob ntawm neuralgia. Lub luag haujlwm tseem ceeb ntawm kev ua yog calcium channel thaiv, thiab tib lub sijhawm - Aminobutyric acid analogs, tab sis txawm tias cov tshuaj muaj kev nyab xeeb tshaj plaws yuav muaj qee yam kev mob tshwm sim tom qab noj ntau dhau. Cov kev mob tshwm sim ntau dua yog raws li hauv qab no:
1. qaug zog thiab qaug zog: tom qab tus neeg mob noj cov tshuaj ntau dhau, xws li ntau dhau los yog siv ntau dhau, kev qaug zog thiab qaug zog tuaj yeem tshwm sim;
2. Kev ua haujlwm tsis zoo ntawm daim siab thiab lub raum: txij li gabapentin yog metabolized los ntawm lub siab thiab lub raum, feem ntau cov tshuaj Western muaj peev xwm ua rau hepatorenal toxicity ntev npaum li lawv tau noj ntau dhau;
3. Cov tshuaj tiv thaiv kab mob hauv plab: vim feem ntau cov gabapentin yog tshuaj ntsiav, ib zaug noj ntau dhau, ntuav ntuav qee zaum tshwm sim, thiab cov tshuaj tiv thaiv kab mob plab yuav mob hnyav heev;
4. Lwm cov tsos mob: xws li chim siab, mob taub hau, kiv taub hau, thiab khaus tawv nqaij, yog tag nrho cov tsos mob atypical.