Sertraline Hcl hmoovyog ib chav kawm xaiv serotonin reuptake inhibitor (SSRIs) siv los kho kev nyuaj siab thiab obsessive -compulsive disorder thiab alleviate clinically cov tsos mob. Nws tsuas yog ua haujlwm los ntawm inhibiting reuptake ntawm serotonin (5-hydroxytryptamine, 5-HT) nyob rau hauv lub hauv nruab nrab lub paj hlwb, yog li nce serotonin concentration nyob rau hauv synaptic cleft thiab pab txhawb 5-hydroxytryptamine neurotransmission. Cov txheej txheem no yog lub hauv paus ntawm nws cov tshuaj tiv thaiv kev nyuaj siab, thiab nws qhov cuam tshuam rau kev rov ua dua ntawm norepinephrine thiab dopamine yog tsawg.
|
Yam khoom |
Specification | Cov txiaj ntsig |
|
Qhov tshwm sim |
Dawb kom tawm hmoov dawb |
Ua raws |
|
tsw |
Yam ntxwv |
Ua raws |
|
Melting point |
116℃-119 degree |
117 ° -117.8 ° C |
|
Residue ntawm ignition |
Tsawg dua lossis sib npaug li 0.1% |
0.05% |
|
LOD |
Tsawg dua los yog sib npaug li 0.5% |
0.21% |
|
Dej |
Tsawg dua lossis sib npaug li 1% |
0.03% |
|
Hais txog |
Ib qho impurity Tsawg dua lossis sib npaug li 0.5% Tag nrho impurity Tsawg dua lossis sib npaug li 1.0% |
Ua raws |
|
Hnyav Hlau |
Tsawg dua lossis sib npaug li 10 ppm |
10 ppm |
|
Tag nrho cov kab mob |
Tsawg dua lossis sib npaug li 1000 cfu / g |
Ua raws |
|
Fungi |
Tsawg dua lossis sib npaug li 100 cfu / g |
Ua raws |
|
Assay |
Ntau dua lossis sib npaug li 98.5% |
99.1% |
| Xaus | Ua raws li kev lag luam specification. |
Dab tsi yog pharmacological kev txiav txim ntawm Sertraline Hcl Powder?
Sertraline Hcl hmoovyog ib qho kev xaiv serotonin reuptake inhibitor (SSRI), uas nws lub luag haujlwm tseem ceeb yog txhawm rau xaiv thiab ua haujlwm zoo inhibit lub serotonin transporter (SERT) ntawm presynaptic neuron membrane, thaiv cov txheej txheem rov ua dua ntawm serotonin (5-HT) hauv synaptic cleft, nce qhov concentration} 5 T cleft hauv nruab nrab, serotonergic neurotransmission. Cov nyhuv no yog kev xaiv heev - nrog rau qhov tsis tshua muaj affinity rau norepinephrine thiab dopamine transporters (tsuas yog 1/1000 txog 1/100 ntawm SERT), yog li muaj kev cuam tshuam tsawg heev rau NE thiab DA systems, zam lub plawv thiab cov tshuaj tiv thaiv kab mob ntawm cov tshuaj tricyclic antidepressants. Tom qab kev sim mus sij hawm ntev ntawm cov nas, qhov nce ntxiv hauv 5-HT qib tuaj yeem ua rau muaj kev hloov pauv ntawm postsynaptic 5-HT receptors (xws li 5-HT1A, 5-HT2A) thiab tswj cov kev taw qhia downstream (xws li nce qhov kev qhia ntawm lub hlwb-derived neurotrophic factoring BDN), thiab cov khoom siv kho mob. Qhov no yog suav hais tias yog ib qho tseem ceeb mechanism rau ncua qhov pib ntawm antidepressant kev ua tau zoo thiab tswj kev kho mob kom tsis txhob rov tshwm sim hauv cov tshuaj. Tsis tas li ntawd, nws tseem tuaj yeem tswj hwm cov kab ke hauv nruab nrab ntsig txog kev ntxhov siab thiab kev yuam los ntawm kev txhim kho 5-HT neurotransmission (xws li inhibiting amygdala overactivation thiab tswj cortical striatal thalamic circuits), yog li tiv thaiv kev ntxhov siab thiab tiv thaiv kev cuam tshuam. Zuag qhia tag nrho, lub hauv paus ntawm nws cov tshuaj pharmacological yog xaiv los txhim kho 5-HT neurotransmission, ua rau muaj kev hloov pauv neuroadaptive, thiab txhim kho kev xav thiab kev txawj ntse.
Txoj kev tshawb fawb toxicological ntawm sertraline hydrochloride hmoov yog dab tsi?
Kev tshawb fawb toxicological ntawmsertraline hydrochloride hmoovFeem ntau suav nrog kev mob toxicity, ntev - lub sij hawm toxicity, kev tsim cov tshuaj toxicity, genetic toxicity thiab carcinogenicity. Cov kev tshawb fawb txog kev mob toxicity qhia tau hais tias ib koob tshuaj loj tuaj yeem ua rau lub hauv nruab nrab lub paj hlwb kev zoo siab, convulsion, ua pa nyuaj siab, thiab lwm yam, tab sis cov kev kho mob index yog dav thiab qhov kev nyab xeeb ntau kuj loj. Ntev- kev tshawb fawb txog kev mob toxicity (rov muab tshuaj los ntawm cov nas thiab dev rau 6 lub hlis mus rau 1 xyoos) tau pom tias cov kev hloov pauv hloov xws li qhov hnyav nce, nce me ntsis ntawm daim siab enzymes thiab proliferation ntawm cov thyroid follicular hlwb yuav raug soj ntsuam ntawm cov koob tshuaj ntau, tab sis tsis pom muaj cov kab mob pathological puas tsuaj. Cov kev tshawb fawb ntawm kev ua me nyuam toxicity qhia tau hais tias cev xeeb tub nas thiab luav tuaj yeem soj ntsuam qeeb embryonic txoj kev loj hlob, qeeb ossification thiab fetal yuag poob thaum muab koob tshuaj sertraline hydrochloride siab thaum lub sij hawm organogenesis, tab sis tsis muaj qhov tseeb teratogenicity pom. Kev siv perinatal tuaj yeem txo qis qhov ciaj sia thiab ua kom qhov hnyav nce ntawm cov tub ntxhais hluas, yog li nws yuav tsum tau ntsuas qhov zoo thiab qhov tsis zoo thaum siv nws thaum cev xeeb tub. Cov txiaj ntsig ntawm genotoxicity test (Ames test, chromosome aberration test thiab micronucleus test) yog txhua yam tsis zoo, thiab tsis muaj kev hloov pauv los yog chromosome breakage. Kev tshawb fawb carcinogenicity (ntev-kev tswj hwm hauv cov nas thiab nas rau 2 xyoos) tau pom tias qhov tshwm sim ntawm hepatocellular adenoma thiab mob qog noj ntshav hauv cov poj niam nas hauv cov koob tshuaj siab tau nce me ntsis, tab sis cov nyhuv yog hom- tshwj xeeb (tsis pom nyob rau hauv nas), thiab cov koob tshuaj tau ntau dua li qhov chaw kuaj mob. Ua ke nrog lwm cov ntaub ntawv toxicological, nws tau txiav txim siab tias nws txoj kev pheej hmoo carcinogenic tsawg heev tam sim no. Feem ntau hais lus,Sertraline Hcl hmoovmuaj kev nyab xeeb ntawm cov koob tshuaj pom zoo, thiab nws cov yam ntxwv toxicological zoo ib yam li lwm cov tshuaj SSRI. Txawm li cas los xij, nws yuav tsum raug sau tseg tias koob tshuaj ntau yuav ua rau muaj kev pheej hmoo ntawm serotonin syndrome, thiab cov pab pawg tshwj xeeb yuav tsum tau kho cov koob tshuaj.
Txoj kev tshawb fawb toxicological ntawm Sertraline Hcl Powder yog dab tsi?
Cov kev mob tshwm sim ntawmSERTRALINE MANDELATE hmoovyog qhov tsis xis nyob hauv plab, xws li xeev siab, anorexia thiab raws plab. Mob taub hau, ntxhov siab vim, qaug zog, lethargy, insomnia, kiv taub hau lossis tshee kuj tshwm sim. Tsis tshua muaj kev phiv tshwm sim muaj xws li ua xua ntawm daim tawv nqaij ua pob liab vog thiab kev sib deev hypofunction. Cov koob tshuaj loj tuaj yeem ua rau qaug dab peg. Tom qab siv nws tam sim ntawd, cov tsiaj sim sim tau ntsib insomnia, ntxhov siab vim, xeev siab, tawm hws, tshee, kiv taub hau lossis lwm yam kev xav txawv txawv.
Muaj ntau txoj kev xa khoom rau koj xaiv
|
Tsheb thauj mus los |
Shipping txoj kev |
Cargo hnyav xav tau |
Qhov zoo |
|
3-7 hnub |
DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, |
Haum rau qis dua 50kg. |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, |
|
7-15 hnub |
Los ntawm Cua |
Haum rau ntau tshaj 50kg. |
|
|
15-60 hnub |
Los ntawm Hiav Txwv |
Haum rau ntau tshaj 500kg. |
Peb lub zog:
Peb lub tuam txhab tau dhau los ntawm FDA thiab ISO19001 kev tswj hwm qhov system ntawv pov thawj. Thiab peb muaj kev koom tes nrog kev cog lus nrog ntau lub Hoobkas thiab chaw kuaj hauv Suav teb, Peb lub tuam txhab tuaj yeem muabSertraline Hcl hmoovthiab lwm yam ntawm tus nqi zoo dua. Yog tias koj txaus siab, thov sau ib tsab ntawv.
Peb tsis tsuas yog muaj qhov tshwj xeeb zoo hauv kev thauj mus los, tab sis kuj txhawb ntau txoj kev them nyiaj, txawm tias koj siv nyiaj US, euros, Australian las, lossis cov nyiaj hauv zos los ntawm Singapore, Malaysia, Thaib, thiab lwm yam. Peb kuj tuaj yeem txhawb cov txiaj ntsig hauv zos hauv cov cheeb tsam thiab cov tebchaws no. Tsis tas li ntawd, peb kuj txhawb nqa cov npav hauv txhab nyiaj (credit cards, thiab lwm yam) rau kev them nyiaj.
FAQ:
Q1: Nws puas yuav nyob ntawm?
Nws tsis muaj kev vam khom thiab yuav tsis ua rau muaj kev quav yeeb quav tshuaj, tab sis nws yuav nres tam sim ntawd tom qab siv sijhawm ntev - thiab muaj qhov txawv txav. Yog li ntawd, yog tias nws yuav tsum tau nres, nws raug nquahu kom maj mam txo cov nyiaj raws li kev qhia ntawm tus kws kho mob.
Q2: Nws puas cuam tshuam rau kev ua haujlwm ntawm kev sib deev?
Yog lawm, sertraline hydrochloride tuaj yeem ua rau muaj kev sib deev tsis zoo, uas feem ntau tshwm sim raws li kev txo qis libido, ncua ejaculation, ncua lossis tsis muaj orgasm. Txawm li cas los xij, nrog kev nce ntawm kev pabcuam lub neej, qee qhov kev kawm tuaj yeem txhim kho.
Q3: Yuav khaws Sertraline Hcl Powder li cas?
Tus qauv cia tej yam kev mob ntawmsertraline hydrochloride API hmoovyog: kaw, tsaus, qhuav thiab khaws cia rau hauv qhov chaw txias. Nws tau pom zoo tias qhov ntsuas kub yuav tsum tau tswj ntawm 2-8℃(txias cia) lossis tsis ntau tshaj 25℃(qhov kub thiab txias qhov chaw) thiab qhov txheeb ze av noo yuav tsum tsis pub tshaj 60%. Cov kev cai tshwj xeeb yuav tsum tau ua raws li cov xwm txheej tau teev tseg hauv phau ntawv qhia khoom lossis COA, uas yuav txawv me ntsis ntawm cov chaw tsim khoom rau cov chaw tsim khoom.
Tsis lees paub: Cov ntaub ntawv luam tawm ntawm lub vev xaib no los ntawm Is Taws Nem, tsis tau txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm cov ntsiab lus. Thov ua tib zoo saib kom paub qhov txawv. Tsis tas li ntawd, cov khoom muab los ntawm peb lub tuam txhab tsuas yog siv rau kev tshawb fawb tshawb fawb. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv tsis raug.
Yog tias koj txaus siab rau peb cov khoom, lossis muaj cov lus qhia tseem ceeb ntawm peb cov khoom lossis tsis txaus siab rau cov khoom tau txais, thov hu rau peb los ntawmEmail :sales6@faithfulbio.com . Peb pab neeg tau cog lus los ua kom tiav kev txaus siab ntawm cov neeg siv khoom.
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