Tadalafil hmoovyog ib qho kev ua tau zoo thiab ntev -} kav cov khoom kom kho ed thiab bph, thiab nws lub zog kawg muab kev ywj pheej uas tsis muaj kev sib deev rau tus txiv neej lub neej. Raws li cov txheeb cais ntawm cov ntaub ntawv lag luam uas muaj feem xyuam rau kev sib deev ntawm cov txiv neej kev sib deev, thiab nws cov leeg ua rau muaj kev sib deev ntawm lub corpus cavernosum thiab coj mus rau cenais erection. Tsis tas li ntawd, api tildenafil hmoov muaj ntau txoj haujlwm ntau ntau thiab feem ntau siv los cuam tshuam nrog kev kub siab ntsws hauv tsev kho mob.
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Yam |
Kev qhia tshwj xeeb |
Qho kawg |
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Kev tshwm sim |
Dawb lossis yuav luag dawb hmoov |
Ua raws |
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So |
Kev ua insoluble hauv dej, ywj siab soluble nyob rau hauv duethyl sulfoxide, me ntsis soluble hauv methylene chloride |
Ua raws |
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Impurities a, b thiab c |
Cov Imurities teev: tsawg dua lossis sib npaug rau 0.10% |
Ua raws |
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Kuv |
IR yuav tsum ua raws li cov ntaub ntawv siv hluav taws xob. |
Ua raws |
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Ib qho kev txheeb ze |
yam zoo |
Ua raws |
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Tag nrho cov impurity: tsawg dua los yog sib npaug rau 0.3% |
0.17% |
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Poob rau ziab |
Tsawg dua los yog sib npaug rau 0.5% |
0.20% |
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Sulfated tshauv |
Tsawg dua los yog sib npaug rau 0.1% |
0.06% |
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Cov hlau hnyav |
Tsawg dua los yog sib npaug rau 20ppm |
Ua raws |
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Cuam tshuam impurity |
Tsawg dua los yog sib npaug rau 0.5% |
0.28% |
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Methanol |
Tsawg dua los yog sib npaug rau 0.3% |
0.021% |
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Methylene Dichhloride |
Tsawg dua los yog sib npaug rau 0.06% |
0.017% |
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N, n - dimethyl formamide |
Tsawg dua los yog sib npaug rau 0.088% |
Tsis pom |
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Assay (ntawm qhuav hauv paus) |
97.5%~102% |
99.57% |
| Xaus: |
Yoog nrog kev lag luam tshwj xeeb. |
Dab tsi yog cov tshuab ntawm kev ua ntawm tadalafil hmoov?
Tadalafil hmoovUa haujlwm los ntawm kev xaiv inhibitivease -5 (pde5). Cov kev tshawb fawb preclinical tau pom tias nws tuaj yeem xaiv tau ntawm PDE5, tab sis muaj cov nyhuv me me ntawm lwm PDE Isozymes xws li PDEky1, PDE2, PDE4 thiab PDE4. Hauv tsev kho mob, nws yog tsuas yog siv rau erectile kawg thiab thiab kev mob siab tawv nqaij:
1. Erectile tsis zoo: raws li cov neeg siv siab siv 5 (PDE5} Kev muag khoom siv rog ntau yam yuav tsis cuam tshuam nrog nws nqus. We know that nitric oxide synthase (NOS) in penile nerve endings and vascular endothelial cells catalyzes the synthesis of nitric oxide (NO) from L-arginine. Tsis muaj kev ua haujlwm guanosine cyclase, uas hloov guanosine triphospüate rau hauv guanosine), uas relaxes {8} Taug kev Hauv cov txheej txheem no, phosphodiesterase hom 5 (PDE5) kuj tseem yuav ua rau lub cev, thiab CGMP yuav ua rau cov khoom lag luam tsis muaj zog, uas yuav tig mus rau tus qau rau hauv lub xeev tsis muaj zog.calaisyog txawv los ntawm lwm cov khoom lag luam nyob rau hauv uas nws tsis ua tiav nws lub hom phiaj los ntawm kev nce ib txoj kev ntawm nitric ofthale, tab sis los ntawm kev tiv thaiv PDE5 degradation.
2. Pulmonary bypertension: Tildenafil yog muaj zog, thim rov qab thiab xaiv cov hlab ntsha tsis muaj / c gmp
Dab tsi yog synthemes txoj kev ntawm tadalafil hmoov?
Pib los ntawm D - tryptophan, d - hydeptophan methyloride yog thawj zaug rau methylation cov tshuaj tiv thaiv. Lub txiaj ntsig d - trychyloride cov tshuaj {}}}}}}}}}}}} kev haus dej hauv isopropylal compound. Nws yog tom qab ntawd ntu ntu nrog chloroac etyl chloride thiab catalyst, nrog rau tag nrho cov txiaj ntsig ntawm 56%. Tom qab ntsuas, acetic acid yog siv los ua cov recrystallization kuab rau kev ua kom huv ntxiv.
Dab tsi yog cov tseem ceeb nta thiab cov txiaj ntsig ntawm tadalafil hmoov?
1. Ntev - kawg: Qhov no yog qhov tshwj xeeb tshaj plaws ntawm Tadalafil. Nws cov nyhuv yuav nyob ntev li ntawm 36 teev. Qhov no muab qhov sib txawv ntau dua rau cov koom tes, thiab tsis tas yuav tsum npaj nruj me ntsis npaj lub sijhawm ntawm kev siv thiab kev sib deev lub neej.
2.
3
Ntau hom kev xa khoom rau koj xaiv
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Tsheb Thauj Mus Los |
Shipping Txoj Kev |
Cargo Qhov hnyav |
Yam uas pab |
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3-7 hnub |
DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, |
Haum rau hauv qab 50kg. |
Peb muaj cov chaw khaws khoom hauv Tebchaws Yelemees thiab California, Asmeskas, |
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7-15 hnub |
Los ntawm huab cua |
Haum rau ntau tshaj 50kg. |
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15-60 hnub |
Los ntawm hiav txwv |
Haum rau ntau tshaj 500kg. |
Peb ua tau zoo:
Peb lub tuam txhab tau dhau FDA thiab ISO19001 kev tswj hwm kev tswj hwm kev ua haujlwm zoo. Thiab peb muaj kev pom zoo sab hauv kev sib koom tes nrog ntau yam khoom lag luam thiab chaw kuaj xyuas hauv Suav teb, peb lub tuam txhab tuaj yeem muabTadalafil hmoovlwm yam. Ntawm tus nqi ntau dua. Yog tias koj txaus siab, thov tso cov lus.
Peb tsis tsuas yog muaj cov txiaj ntsig tshwj xeeb hauv kev thauj mus los, tab sis kuj tseem txhawb ntau txoj kev them nyiaj, seb koj puas siv nyiaj US los ntawm Singapore, thiab nyob rau hauv Singapore, Malaysia, thiab lwm yam. Peb tseem tuaj yeem txhawb cov nyiaj hauv zos hauv cov cheeb tsam thiab cov teb chaws. Ib qho ntxiv, peb kuj txhawb nqa cov npav nyiaj hauv tuam txhab (credit card, thiab lwm yam) rau kev them nyiaj.
FAQ:
Q1. Dab tsi yog tadalafil?
Tadarafe yog tsuas yog siv los kho erectile kawg (ED) thiab benign prostatic hyperplasia (bpph). Nws zwm rau chav kawm ntawm cov kws tshuaj uas hu ua phosphodiesteres hom 5 (PDE5) inhibitors.
Q2. Puas yog Tadalafil nyab xeeb rau cov txiv neej muaj teeb meem plawv?
Cov txiv neej nrog cov kab mob plawv yuav tsum raug ntsuas ua ntej sau tadalafil. Kev sib deev yuav tso siab rau lub siab. Koj tus kws kho mob yuav txiav txim siab tias koj lub siab puas muaj kev noj qab haus huv txaus kom muaj kev sib deev thiab siv cov tshuaj no.
Q3. Puas yog cov tshuaj uas tsis muaj tshuaj tadalafil kom zoo raws li lub npe lag luam cialis?
Yog lawm tadalafil muaj tib cov khoom xyaw nquag ua lag luam pialis. Nws tau pom zoo los ntawm FDA, uas tseem muaj kev nyab xeeb thiab ua tau zoo, tab sis tus nqi yog qis dua.
Q4. Kuv puas tuaj yeem siv cov zaub mov nrog tadalafil?
Yog lawm, Tadalafil tuaj yeem nrog cov khoom noj. Ntxiv mus, siab - cov zaub mov muaj roj yuav tsis pub dhau nws cov kev nqus.
Kev tsis lees paub: Cov ntaub ntawv tau luam tawm hauv lub vev xaib no los ntawm Is Taws Nem, uas tsis txhais tau tias lub vev xaib no pom zoo nrog nws cov kev pom lossis lees paub meej txog cov ntsiab lus. Thov saib xyuas kom paub qhov txawv nws. Ib qho ntxiv, cov khoom muab los ntawm peb lub tuam txhab tsuas yog siv rau kev tshawb fawb. Peb tsis yog lub luag haujlwm rau lub txim ntawm kev siv tsis raug.
Yog tias koj txaus siab rau peb cov khoom, lossis muaj cov lus tseem ceeb ntawm peb cov lus lossis tsis txaus siab kiag li nrog cov khoom tau txais, thov hu rau peb los ntawmTus email :sales6@faithfulbio.com Cov. Peb pab neeg tau cog lus los ua kom tiav cov kev txaus siab tiav ntawm cov neeg siv khoom.
Cim npe nrov: Tadalafil hmoov CAS 171596-29-5-5, cov chaw muag khoom, chaw tsim tshuaj paus, kev lag luam, cov khoom siv dawb, tsim khoom, ua nyob rau hauv Suav teb