Dulaglutide Peptide hmoov CAS 923950-08-7

Dulaglutide peptide hmoov CAS 923950-08-7yog ib qho ntev - ua glucagon- zoo li peptide-1 receptor agonist (GLP-1 RA) feem ntau siv rau kev tswj glycemic thiab tswj kev pheej hmoo ntawm cov hlab plawv hauv hom 2 mob ntshav qab zib, nrog rau kev ua siab zoo raws li qhov tseem ceeb. Cov khoom xyaw nquag hauv Dulaglutide, Dulaglutid, yog GLP-1 receptor agonist. Nws cov txheej txheem ntawm kev ua haujlwm zoo ib yam rau GLP-1 (ib yam tshuaj hormones tsim hauv lub plab), pab tswj cov ntshav qab zib thiab cov tsos mob ntawm hom 2 mob ntshav qab zib los ntawm kev nce qhov tso tawm ntawm cov tshuaj insulin uas ua los ntawm cov txiav ua rau cov zaub mov stimulation.

Dulaglutide ua rau cov kab mob pancreatic los ntawm kev ua kom cov kab mob intracellular cyclic adenosine monophosphate (cAMP), uas nyob rau hauv lem activates adenylate cyclase, nce cAMP qib hauv cov hlwb. Qhov no txhawb nqa cov tshuaj insulin hloov pauv, kev tsim cov tshuaj insulin, thiab tso tawm. Tib lub sijhawm, nws txhawb kev loj hlob ntawm tes thiab sib txawv, inhibits apoptosis, thiab nce cov xov tooj ntawm tes, yog li tiv thaiv cov hlwb. Dulaglutide kuj ua rau cov hlwb pancreatic, inhibiting glucagon tso tawm. Tsis tas li ntawd, los ntawm kev ua haujlwm ntawm pancreatic δ hlwb, nws txhawb nqa somatostatin secretion, uas nyob rau hauv lem inhibits glucagon secretion. GLP-1 kuj tseem ua rau lub sijhawm ua rau lub plab zom mov, yog li qeeb kev nqus cov khoom noj thiab txo qis cov ntshav qabzib tom qab.