Fosgonimeton CAS 2093305-05-4

ATH-1017 Taw qhia

Xi'an Faithful BioTech Co., Ltd., nrhiav tau nyob rau hauv 2018 thiab raws li nyob rau hauv Xi'an, Tuam Tshoj, yog ib tug export-focused biotech & tshuaj tub luam. Peb tshwj xeeb hauv cov tshuaj intermediates, cog extracts, zaub mov additives thiab pub khoom xyaw rau cov neeg yuav khoom thoob ntiaj teb B2B. Peb xa cov khoom lag luam ruaj khov nrog QC nruj, tus nqi sib tw, cov sij hawm ua cov khoom lag luam thiab cov kev pabcuam xa tawm tag nrho, pabcuam cov kws kho mob, kev noj qab haus huv ntxiv, tshuaj pleev ib ce thiab pub kev lag luam thoob plaws Tebchaws Europe, North America, Southeast Asia thiab Middle East.

Fosgonimeton (ATH-1017) yog ib qho me me molecule innovative compound tsim los ntawm Athira Pharma. Nws cov txheej txheem tseem ceeb ntawm kev ua haujlwm yog nyob rau hauv kev tswj hwm lub siab cell loj hlob yam zoo (HGF) / MET signaling pathway. Los ntawm kev ua kom cov neurotrophic, neuroprotective thiab anti-inflammatory pathways nyob rau hauv lub hauv paus paj hlwb, nws lub hom phiaj los hais txog cov complex pathological txheej txheem ntawm neurodegenerative kab mob. Hauv kev tshawb fawb preclinical,Fosgonimetonpom tau tias muaj peev xwm tiv thaiv kev puas tsuaj ntawm neuronal thiab autophagy dysfunction tshwm sim los ntawm -amyloid protein (A ), thiab tau cuam tshuam nrog kev paub txog kev ua haujlwm. Tam sim no, Fosgonimeton (ATH-1017) tau nkag mus rau theem kev sim tshuaj, thiab feem ntau yog tsim los rau kev kho mob Alzheimer's disease (AD). Cov ntaub ntawv kev nyab xeeb ntsig txog lwm yam kev qhia xws li Parkinson's disease dementia thiab Lewy lub cev dementia kuj tau tshaj tawm hauv kev tshawb nrhiav.
CAS Nr .: 2093305-05-4; Cov mis mos molecular: C27H45N4O8P; Molecular Luj: 584.65

ATH-1017 siv nws li cas ntawm qib cellular?

Nws tuaj yeem suav tau tias yog ib hom "sib nqus ua kom zoo dua".Fosgonimetontsis ncaj qha hloov cov neurons lawv tus kheej, tab sis ua rau cov receptor complexes ntawm lub xovtooj ntawm tes, ua rau cov paj hlwb ntau rhiab heev rau "cim ciaj sia taus" hauv ib puag ncig ib puag ncig - hepatocyte kev loj hlob. Thaum lub teeb liab tau nthuav dav, ntau txoj hauv kev tiv thaiv hauv lub hlwb yuav qhib, suav nrog inhibiting kev tso tawm ntawm cov kab mob inflammatory, tswj lub zog ntawm mitochondria, thiab pib rov ua dua cov txheej txheem ntawm cov protein puas. Qhov no yog sib npaug los muab cov txheej txheem ntxiv ntawm kev tiv thaiv rau cov neurons hauv lub xeev kev ntxhov siab.

Sib nrug los ntawm Alzheimer's kab mob, lwm yam kab mob dab tsi tau tshawb nrhiav ATH-1017?

Cov kws tshawb fawb tau nthuav dav daim ntawv thov ntawmFosgonimetonrau lwm cov kab mob hauv lub hlwb uas tshwm sim los ntawm qhov txawv txav ntawm cov protein deposition. Piv txwv li, nyob rau hauv preclinical qauv ntawm Parkinson tus kab mob dementia thiab Lewy lub cev dementia, ATH-1017 tau soj ntsuam los txo cov synaptic dysfunction los ntawm -synuclein. Tsis tas li ntawd, muaj cov kev tshawb fawb tsis ntev los no tsom mus rau nws lub luag haujlwm hauv lub sijhawm mob ntev tom qab raug mob lub hlwb, tab sis feem ntau ntawm cov lus qhia no tseem nyob ntawm cov pov thawj thaum ntxov - ntawm - lub tswv yim theem thiab tsis tau nkag mus rau qhov kev sim loj loj.

MF ntawm Fosgonimeton (ATH-1017)

CAS	2093305-05-4
Cov mis mos molecular	C27H45N4O8P
Molecular hnyav	584.65
Daim ntawv	Khoom
Acidity coefficient	1.27±0.30
Qhov ntom	1.212 ± 0.06 g / cm3

Specification

Nyem email:sales6@faithfulbio.comLos yog WhatsApp:+86 17782780648

Muaj ntau txoj kev xa khoom rau koj xaiv

Peb lub zog:

Peb lub tuam txhab tau dhau los ntawm FDA thiab ISO19001 kev tswj hwm qhov system ntawv pov thawj. Thiab peb muaj kev koom tes nrog kev cog lus nrog ntau lub Hoobkas thiab chaw kuaj hauv Suav teb, Peb lub tuam txhab tuaj yeem muabFosgonimetonthiab lwm yam ntawm tus nqi zoo dua. Yog tias koj txaus siab, thov sau ib tsab ntawv.
Peb tsis tsuas yog muaj qhov tshwj xeeb zoo hauv kev thauj mus los, tab sis kuj txhawb ntau txoj hauv kev them nyiaj, txawm tias koj siv nyiaj US, euros, Australian las, lossis cov nyiaj hauv zos los ntawm Singapore, Malaysia, Thaib, thiab lwm yam. Peb kuj tuaj yeem txhawb cov txiaj ntsig hauv zos hauv cov cheeb tsam thiab cov tebchaws no. Tsis tas li ntawd, peb kuj txhawb nqa cov npav hauv txhab nyiaj (credit cards, thiab lwm yam) rau kev them nyiaj.

FAQ:

Q1: Dab tsi yog qhov profile ntawm ATH-1017?
Kev nyab xeeb tag nrho tau suav tias yog qhov tsim nyog, thiab qhov tshwm sim ntawm cov xwm txheej tsis zoo yog sib npaug ntawm ob pawg. Txawm li cas los xij, muaj qhov xwm txheej tseem ceeb: qhov kev tso tawm hauv pawg ATH-1017 (14.2%) tau nce siab dua li hauv pawg placebo (4.6%), thiab qhov laj thawj tseem ceeb ntawm kev tso tawm yog qhov tsis zoo cuam tshuam txog kev siv cov tshuaj no.
Q2: ATH-1017 ua li cas hauv kev sim tsiaj?

Nws qhia tau tias muaj txiaj ntsig zoo hauv ntau hom tsiaj. Piv txwv li, nws tuaj yeem thim rov qab qhov kev nco tsis zoo tshwm sim los ntawm Scopolamine, txhim kho cov teeb liab tsis zoo ntawm Choline hydroxide; thiab tseem tiv thaiv kev puas hlwb los ntawm neuroinflammation induced los ntawm lipopolysaccharide (LPS). Cov txiaj ntsig no muab qee lub hauv paus rau nws nkag mus rau hauv tib neeg kev sim tshuaj.

Q3: Nws puas tuaj yeem hla cov ntshav - lub hlwb thaiv?

Qhov no yog ib qho ntawm cov hom phiaj ntawm kev tsim ntawm nws cov khoom ua ntej. ATH-1017 nws tus kheej muaj qhov zoo dua solubility thiab ruaj khov, thiab tuaj yeem nkag mus rau hauv nruab nrab paj hlwb los ntawm cov hlab ntsha. Tom qab nkag mus rau hauv lub hlwb, nws mam li hloov mus rau hauv ib qho active metabolite, uas tom qab ntawd ua haujlwm ntawm cov paj hlwb ntawm lub hom phiaj qhov chaw - uas yog, nyob rau hauv lub hlwb cov ntaub so ntswg.

Tsis lees paub: Cov ntaub ntawv luam tawm ntawm lub vev xaib no los ntawm Is Taws Nem, tsis tau txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm cov ntsiab lus. Thov ua tib zoo saib kom paub qhov txawv. Tsis tas li ntawd, cov khoom muab los ntawm peb lub tuam txhab tsuas yog siv rau kev tshawb fawb tshawb fawb. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv tsis raug.

Yog tias koj txaus siab rau peb cov khoom, lossis muaj cov lus qhia tseem ceeb ntawm peb cov khoom lossis tsis txaus siab rau cov khoom tau txais.

Nyem email:sales6@faithfulbio.comLos yog WhatsApp:+86 17782780648

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