Thymalfasin CAS 69440-99-9

Thymalfasin yog ib qho protein thiab peptide hormone nrog kev tiv thaiv kev tiv thaiv kev ua haujlwm uas tsim los ntawm thymic superficial cortex thiab medulla epithelial hlwb. Nws yog ib qho acidic peptide tsim los ntawm 28 amino acids thiab yog cov tshuaj lom neeg ua haujlwm. Hauv cov tshuaj, nws cov kev ua haujlwm lom neeg yog qhov dav. Tam sim no, nws yog tsuas yog siv rau kev kho mob ntawm immunodeficiency, kab mob kis thiab qog. Nws yog ib qho kev lees paub thawj zaug - cov khoom lag luam rau kev kho kab mob siab B, thiab tseem tuaj yeem siv los ua cov khoom siv raw rau cov tshuaj tiv thaiv, nrog rau kev kho mob tseem ceeb. Nws muaj qhov zoo ntawm kev ua haujlwm siab heev, cov tshuaj lom neeg tsawg tsawg, thiab siv dav dav. CovThymosin Alpha 1 raw hmoovpeb muab yog chemically synthesized tshuaj raw khoom. Txawm li cas los xij, nws cov khoom siv tshuaj lom neeg thiab spatial zoo ib yam nrog tib neeg thymosin alpha 1, kom ntseeg tau tias nws cov haujlwm lom neeg kuj zoo ib yam nrog tib neeg thymosin alpha 1.

Dab tsi yog pharmacological kev txiav txim ntawm Thymalfasin?

Ntuj Thymosin 1 tuaj yeem ua lub luag haujlwm antiviral, antitumor thiab immunomodulatory hauv kev tsim cov T hlwb, suav nrog kev hloov pauv ntawm qia hlwb mus rau T hlwb, kev sib txawv ntxiv thiab kev loj hlob ntawm T hlwb. Txawm hais tias lub mechanismThymalfasin nyoos hmoovHauv kev kho kab mob siab B ntev thiab txhim kho kev ua haujlwm ntawm lub cev tiv thaiv kab mob tseem nyob rau theem inference, ntau qhov kev sim hauv vitro qhia tau hais tias nws tuaj yeem txhawb kev loj hlob ntawm T lymphocytes los ntawm stimulating mitogen ntawm peripheral ntshav lymphocytes, nce lymphatic yam theem ntawm interferon , interferon , interleukin genit 2 thiab interleukin zais cia hlwb tom qab. ua kom, thiab nyob rau tib lub sij hawm nce qib ntawm lymphatic yam receptor nyob rau saum npoo ntawm T hlwb. Nws tseem tuaj yeem txhim kho tib neeg cov tshuaj tiv thaiv lymphocyte ntawm allogeneic thiab autologous hlwb los ntawm kev ua kom CD4 hlwb. Thaum kawg, nws tau pom tias nws tuaj yeem nce qhov sib sau ua ntej -NK hlwb, thiab interferon tuaj yeem txhim kho nws cov cytotoxicity. Qhov sib txawv hauv vivo thwmsim qhia tau tias Thymalfansin tuaj yeem nce qib kev qhia ntawm interleukin-2 receptor hauv lymphocytes ntawm cov nas qhib los ntawm concanavalin A, thiab tib lub sijhawm nce qib zais cia ntawm interleukin-2. Los ntawm cov saum toj no, nws plays lub luag hauj lwm nyob rau hauv tag nrho cov txheej txheem.

Dab tsi yog qhov txawv ntawm Thymalfasin thiab thymopentin?

Thymalfasin hmoov yog peptide tsim los ntawm 28 amino acids, thaum Thymopentin yog ib feem ntawm 5 amino acids. Ob leeg pib los ntawm thymus, tab sis yav dhau los muaj kev tswj hwm kev tiv thaiv kab mob ntau dua thiab cov ntaub ntawv tshawb fawb zoo dua, feem ntau yog siv rau cov kab mob siab B, mob qog noj ntshav, thiab lwm yam; Cov tom kawg yog tsuas yog siv rau kev tiv thaiv kab mob, kab mob autoimmune, thiab lwm yam. Qhov sib piv ntawm ob yog raws li hauv qab no:
1. Molecular qauv thiab muaj pes tsawg leeg
Thymalfasin yog ib qho hluavtaws peptide tsim los ntawm 28 amino acids, nrog rau qhov hnyav molecular ntawm kwv yees li 3108 daltons. Nws lub ntsiab tivthaiv yog thymosin alpha 1; Thymopentin nyoos hmoov yog tsim los ntawm tsuas yog 5 amino acids thiab muaj ib qho hnyav molecular ntawm kwv yees li 679 daltons, ua rau nws muaj txiaj ntsig zoo ntawm thymopoietin II.
2. Mechanism ntawm kev txiav txim thiab kev qhia
Thymalfasin tswj lub cev tiv thaiv kab mob los ntawm ntau lub hom phiaj xws li txhawb kev sib txawv ntawm T cell thiab kev loj hlob, txhim kho NK cell kev ua, thiab feem ntau yog siv los txhim kho cov tshuaj tiv thaiv hauv cov neeg mob uas muaj kab mob siab B, mob qog noj ntshav, thiab kev tiv thaiv kab mob; Thymopentin feem ntau induces T cell sib txawv, tswj qhov feem ntawm T lymphocyte subsets, thiab yog haum rau kev tiv thaiv kab mob tom qab mob kab mob siab B, T cell deficiency kab mob, thiab qog radiotherapy thiab chemotherapy.
3. Kev nyab xeeb txawv
Cov qub muaj kev nyab xeeb dua, tsis tas yuav tsum tau kuaj tawv nqaij, thiab muaj kev cuam tshuam tsawg dua; Kev nyab xeeb ntawm Thymopeptide zoo ib yam li Thymosin Alpha-1, tab sis cov kev phiv xws li xeev siab thiab kub taub hau tseem tuaj yeem tshwm sim. Txawm li cas los, nws tag nrho tolerability yog zoo.

Thymalfasin tus transdermal npaum li cas piv rau lwm yam immunomodulators hauv cov khoom tu tawv nqaij?

Raws li tau hais ua ntej, nws tsuas yog siv rau cov kab mob xws li qog, kab mob sib kis, kab mob siab viral uas xav tau kev txhim kho hauv lub cev tiv thaiv kab mob, nrog rau cov tshuaj tiv thaiv kab mob tiv thaiv kab mob rau cov neeg mob tiv thaiv kab mob. Tab sis nrog kev txhim kho ntawm cov thev naus laus zis tshiab, nws tau maj mam siv rau hauv kev zoo nkauj thiab kev tu tawv nqaij.
Raws li kev lag luam tawm tswv yim, nws tau pom zoo nkag mus rau hauv cov khoom tu tawv nqaij, nrog rau hauv vitro nkag mus rau ntau dua 89%, thiab tuaj yeem nkag mus tob rau hauv cov txheej txheem dermis kom ua tau zoo. Nws qhov hnyav molecular yog txog 3108 daltons, thiab nws muaj zog zoo ntawm pH ntawm lub cev. Nws tuaj yeem cuam tshuam nrog qhov tsis zoo ntawm biomolecules ntawm daim tawv nqaij txhawm rau txhim kho kev nqus ntawm transdermal. Yog hais tias qhov tseeb liposome encapsulation tshuab siv, tus nqi transdermal ntawmThymosin 1tuaj yeem nce ntxiv mus rau 78%, uas yog 2.3 npaug ntau dua li cov qauv tshuaj ib txwm muaj. (Technical popularization: Liposome thev naus laus zis yog ua raws li cov qauv phospholipid bilayer, simulating cov yam ntxwv ntawm cov kab mob lom neeg kom ua tiav encapsulation thiab tso tawm cov tshuaj nquag. Nws tuaj yeem ua haujlwm zoo nrog cov qauv lipid ntawm stratum corneum thiab txhawb peptide nkag mus los ntawm daim tawv nqaij barrier.) Ntxiv nrog rau kev hloov pauv ntawm xibtes. thymalfasin) tuaj yeem txhim kho transdermal absorption muaj peev xwm ntxiv, thiab cov lipid saw tuaj yeem tawg los ntawm stratum corneum barrier, uas ua rau 5-fold nce hauv transdermal tus nqi piv rau cov uas tsis yog acylated peptides. Cov thev naus laus zis no txhais tau tias ua kom nws nkag mus rau hauv cov txheej txheem dermis, qhib fibroblasts, txhawb collagen thiab elastin synthesis, thiab ua tiav qhov kev ncua sijhawm ntawm kev yees duab thiab glycation puas los ntawm qhov chaw.

Muaj ntau txoj kev xa khoom rau koj xaiv

Peb lub zog:

Peb lub tuam txhab tau dhau los ntawm FDA thiab ISO19001 kev tswj hwm qhov system ntawv pov thawj. Thiab peb muaj kev koom tes nrog kev cog lus nrog ntau lub Hoobkas thiab chaw kuaj hauv Suav teb, Peb lub tuam txhab tuaj yeem muabThymalfasin CAS 69440-99-9 thiab lwm yam ntawm tus nqi zoo dua. Yog tias koj txaus siab, thov sau ib tsab ntawv.
Peb tsis tsuas yog muaj qhov tshwj xeeb zoo hauv kev thauj mus los, tab sis kuj txhawb ntau txoj kev them nyiaj, txawm tias koj siv nyiaj US, euros, Australian las, lossis cov nyiaj hauv zos los ntawm Singapore, Malaysia, Thaib, thiab lwm yam. Peb kuj tuaj yeem txhawb cov txiaj ntsig hauv zos hauv cov cheeb tsam thiab cov tebchaws no. Tsis tas li ntawd, peb kuj txhawb nqa cov npav hauv txhab nyiaj (credit cards, thiab lwm yam) rau kev them nyiaj.

FAQ:

Q1: Nws puas tuaj yeem siv nrog lwm yam khoom?
Okay. Thymalfasin feem ntau yog siv ua ke nrog cov tshuaj tiv thaiv kab mob xws li interferon thiab nucleoside analogues los kho tus kab mob siab B, los yog ua ke nrog cov tshuaj kho mob los txhim kho kev tiv thaiv kab mob. Tam sim no, tsis pom muaj kev sib cuam tshuam ntawm cov tshuaj.
Q2: Nws khaws cia li cas?
Tsis qhibThymalfasin hmoovyuav tsum tau txias ntawm 2-8℃kom tsis txhob khov. Cov kua yaj yuav tsum tau siv tam sim ntawd. Yog tias nws tsis tuaj yeem siv tam sim ntawd, nws tuaj yeem khaws cia ntawm 2-8℃tsis pub dhau 24 teev.
Q3: Yuav ua li cas yaj nws?
Dissolve nyob rau hauv 1.0mL sterile dej thiab maj mam co kom txog thaum yaj tag. Cov tshuaj yuav tsum yog cov kua uas tsis muaj xim lossis daj me ntsis. Yog tias cov tshuaj pom tias muaj turbid los yog nag lossis daus, nws yuav tsum tsis txhob siv.
Q4: Nws puas yuav cuam tshuam rau kev ua haujlwm ntawm cov tshuaj tiv thaiv?
Thymosin Alpha 1 tuaj yeem txhim kho lub cev tiv thaiv kab mob ntawm cov tshuaj tiv thaiv, tab sis cov teebmeem tshwj xeeb txawv nyob ntawm seb hom tshuaj tiv thaiv thiab qhov sib txawv ntawm tus kheej. Nws raug nquahu kom mus ntsib kws kho mob ua ntej txhaj tshuaj tiv thaiv.

Tsis lees paub: Cov ntaub ntawv luam tawm ntawm lub vev xaib no los ntawm Is Taws Nem, tsis tau txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm cov ntsiab lus. Thov ua tib zoo saib kom paub qhov txawv. Tsis tas li ntawd, cov khoom muab los ntawm peb lub tuam txhab tsuas yog siv rau kev tshawb fawb tshawb fawb. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv tsis raug.

Yog tias koj txaus siab rau peb cov khoom, lossis muaj cov lus qhia tseem ceeb ntawm peb cov khoom lossis tsis txaus siab rau cov khoom tau txais, thov hu rau peb los ntawmEmail :sales6@faithfulbio.com . Peb pab neeg tau cog lus los ua kom tiav kev txaus siab ntawm cov neeg siv khoom.

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