Diosgenin 98% Hmoov CAS 512-04-9

Diosgemom Taw Qhia

Xi'an Faithful BioTech Co., Ltd. yog ib qho export -oriented biotechnology thiab chemical trading tuam txhab headquartered nyob rau hauv Xi'an, Shaanxi Province, Suav teb. Founded hauv 2018, lub tuam txhab tsom mus rau kev muab tshuaj intermediates, cog extracts, zaub mov additives, thiab pub cov khoom xyaw rau lub ntiaj teb no B2B lag luam.

Raws li ib tug ntshiv, tus neeg muab khoom, peb siv nruj tswj xyuas kom ntseeg tau batch stability thiab ua raws. Nrog rau pab pawg muag khoom thoob ntiaj teb, peb muab cov nqi sib tw heev, lub sijhawm xa khoom tuaj yeem ntseeg tau, thiab ib qho - nres cov kev pabcuam xa tawm.

Peb cov khoom tau dav nkag mus rau cov kws kho mob, kev noj qab haus huv ntxiv, tshuaj pleev ib ce, thiab cov khoom noj khoom haus hauv Tebchaws Europe, North America, Southeast Asia, thiab Middle East.

Diosgenom yog muab rho tawm los ntawm cov hauv paus hniav thiab stems ntawm tuberous nroj tsuag xws li Dioscorea thiab Wild Yam PE Diosgenine, nrog rau cov ntsiab lus ntawm 7% mus rau 16%. Nws tuaj yeem raug cais tawm los ntawm cov noob ntawm fenugreek. Nws belongs rau lub ntuj tsim steroids (25R)-5ALPHA-SPIROSTAN-2ALPHA, 3BETA-DIOL.
Diosgenin 98% hmoovCAS Nr .: 512-04-9; Cov mis mos molecular: C27H42O3; Molecular hnyav: 414.63; PIB: 208-134-3.
Hauv kev lag luam kws tshuaj, nws yog cov khoom siv tseem ceeb rau kev tsim khoom ntawm ntau yam khoom steroid. Clinical feem ntau siv cov tshuaj hormones xws li Progesterone tag nrho tso siab rau nws ua cov khoom siv raw.
Tsis tas li ntawd, ntau qhov kev sim ua ntej kev sim tau lees paub tias Diosgemom tuaj yeem tswj cov metabolism hauv qab zib thiab lipids hauv lub cev, thiab tseem muaj cov tshuaj tiv thaiv antioxidant thiab tiv thaiv - cov teebmeem inflammatory. Qee qhov kev tshawb fawb kuj pom tias nws muaj qee yam los tiv thaiv - qog nqaij hlav. Yog li ntawd, txoj kev loj hlob ntawm cov zaub mov noj qab haus huv thiab kev tshawb fawb ntawm cov tebchaw tshiab yog tam sim no tsom mus rau kev tshawb fawb ntawm cov khoom siv no.

Yuav ua li cas yog lub mechanism ntawm kev txiav txim ntawm diosgenin?

Diosgenin muaj ntau lub hom phiaj ntawm kev nqis tes ua thiab nws cov haujlwm tag nrho tuaj yeem muab faib ua peb yam tseem ceeb: txhawb nqa cell apoptosis, tiv thaiv - cuam tshuam thiab antioxidant, thiab tswj lub cev metabolism.
Rau cov qog-txog kev sim, nws tuaj yeem tsav cov qog hlwb ntawm apoptosis: nws txhawb nqa cov mitochondrial fusion protein MFN2, ua rau PINK1/Parkin txoj hauv kev- kho cov mitochondrial autophagy, yog li inducing apoptosis ntawm daim siab mob hlwb; Nyob rau tib lub sijhawm, nws hloov pauv qhov piv txwv ntawm Bax thiab Bcl-2, qhib cov caspase-txog cov tshuaj tiv thaiv enzymatic, thiab pib qhov kev pab cuam mitochondrial{10}}mediated apoptotic program. Tsis tas li ntawd, nws tuaj yeem tswj cov qog nqaij hlav qog p53, thaiv cov PI3K / AKT, ERK, JNK, thiab NF-κB cov kev taw qhia uas tswj cov cell ciaj sia, yog li inhibiting qog cell ciaj sia thiab kev loj hlob ntawm ntau txoj hauv kev.
Nyob rau hauv cov nqe lus ntawm alleviating o thiab tshem tawm oxidative puas tsuaj,Diosgenin 98% hmoovtuaj yeem txo cov qib phosphorylation ntawm Src / STAT3 cov proteins, yog li txo cov lipid metabolism thiab txo qhov mob hauv lub cev; Nyob rau tib lub sijhawm, nws nce qib Glutathione thiab rov ua haujlwm ntawm ntau yam antioxidant enzymes, tshem tawm cov pa oxygen reactive ROS tsim los ntawm mitochondria, thiab txo qhov kev puas tsuaj los ntawm oxidative kev nyuaj siab rau cov hlwb.
Metabolic-cov kev tshawb fawb ntsig txog kuj tau lees paub tias Diosgenin tuaj yeem cuam tshuam rau PI3K-Akt taw qhia txoj hauv kev, txhim kho cov txheej txheem fatty acid metabolism, thiab muaj kev txhim kho ntawm metabolic- cuam tshuam txog kev puas tsuaj xws li tsis yog - cawv fatty siab kab mob.
Zuag qhia tag nrho, ntau txoj hauv kev ua haujlwm no ua haujlwm ua ke los txhawb cov tshuaj pharmacological ntawm Diosgenin hauv kev tiv thaiv qog nqaij hlav, tiv thaiv kab mob plawv, thiab txhim kho cov ntshav qab zib thiab qib lipid.

Vim li cas diosgenin muaj ntau yam haujlwm lom neeg?

Lub cim tseem ceeb zoo ntawm Diosgenin stems los ntawm nws tus kheej steroid core qauv, uas yog tsim los ntawm interconnection ntawm plaub carbon rings. Nws muaj peb lub rau- cov nplhaib koom ua ke thiab ib qho tsib- lub nplhaib koom nrog, thiab tag nrho peb - qauv qauv yog ruaj khov thiab tsis tu ncua, zoo ib yam li lub hauv paus txheej txheem ntawm endogenous steroid tshuaj tsim los ntawm tib neeg lub cev.
Cov qauv molecular zoo sib xws no muab sijhawm rau Diosgenin los koom nrog thiab tswj hwm ntau yam endogenous steroid-txog cov txheej txheem hloov pauv hauv lub cev. Tsis tas li ntawd, lactone sab saw txuas rau qhov kawg molecular kuj ua lub luag haujlwm tseem ceeb. Los ntawm kev tso siab rau nws qhov tshwj xeeb spatial configuration, nws tuaj yeem haum thiab sib koom ua ke rau hauv cov qauv ntawm cov cell membrane, hloov cov fluidity ntawm cov txheej membrane, thiab ncaj qha khi rau ntau yam intracellular teeb liab tswj cov proteins, xws li PI3K, AKT, thiab NF-κB, uas yog cov proteins txoj hauv kev.
Synthetic internal-derivative qauv ntawm cov tub ntxhais ua ke nrog kev ua haujlwm tshwj xeeb ntawm cov saw hlau sab, thaum sib xyaw ua ke, ua rauDiosgenin 98% hmoovua ib txhij ua ntawm ntau txoj kev tswj hwm: nws tuaj yeem txhim kho qhov kev qhia ntawm pro-apoptotic proteins Bax, txo qib ntawm anti-apoptotic protein Bcl-2, pib mitochondrial-txog apoptotic cov txheej txheem tswj; nws tseem tuaj yeem txwv kev hloov pauv ntawm NF-κB mus rau lub cell nucleus, txo qhov kev tso tawm ntau yam cuam tshuam txog kev mob; thiab nws tseem tuaj yeem qhib txoj hauv kev AMPK teeb liab, tswj cov metabolic tshuav ntawm cov piam thaj thiab lipids hauv lub cev.
Hauv cov ntsiab lus yooj yim, lub ntuj active molecule ntawm Diosgenin tsis tsuas yog ua ntawm ib qho chaw ua haujlwm xwb. Cov qauv tshuaj ntawm cov molecule inherently endows nws nrog cov yam ntxwv ntawm synchronous kev cai ntawm ntau txoj kev, yog li ua rau nws mus rau ib txhij cuam tshuam nyob rau hauv ntau yam txawv txav physiological xeev ntawm lub cellular theem.

MF ntawm Diosgemom

CAS	512-04-9
Cov mis mos molecular	C27H42O3
Molecular hnyav	414.63
EINECS	208-134-3
Melting point	205-208 degree
Boiling point	473.46 qib

Specification

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Muaj ntau txoj kev xa khoom rau koj xaiv

Peb lub zog:

Peb lub tuam txhab tau dhau los ntawm FDA thiab ISO19001 kev tswj hwm qhov system ntawv pov thawj. Thiab peb muaj kev koom tes nrog kev cog lus nrog ntau lub Hoobkas thiab chaw kuaj hauv Suav teb, Peb lub tuam txhab tuaj yeem muabDiosgenin 98% hmoovthiab lwm yam ntawm tus nqi zoo dua. Yog tias koj txaus siab, thov sau ib tsab ntawv.
Peb tsis tsuas yog muaj qhov tshwj xeeb zoo hauv kev thauj mus los, tab sis kuj txhawb ntau txoj hauv kev them nyiaj, txawm tias koj siv nyiaj US, euros, Australian las, lossis cov nyiaj hauv zos los ntawm Singapore, Malaysia, Thaib, thiab lwm yam. Peb kuj tuaj yeem txhawb cov txiaj ntsig hauv zos hauv cov cheeb tsam thiab cov tebchaws no. Tsis tas li ntawd, peb kuj txhawb nqa cov npav hauv txhab nyiaj (credit cards, thiab lwm yam) rau kev them nyiaj.

FAQ:

Q1: Vim li cas peb - qauv ntawm diosgenin tuaj yeem haum rau lub cell membrane?
Lub sab saw ntawm lorcosterone muaj qhov tshwj xeeb spatial configuration, uas tuaj yeem nkag mus rau hauv daim nyias nyias thiab hloov cov yam ntxwv fluidity ntawm cov cell membrane.
Q2: Thaum ua cov kev sim ntawm qib cellular, hom cell qauv twg yog Diosgenin feem ntau siv los tsim?
Lipid metabolism tsis meej cell qauv, oxidative puas cell qauv, txawv txav proliferation cell qauv.
Q3: Puas yog Diosgenin nce DHT?

Hauv kev tshawb fawb dhau los, kev kho Diosgenin tau pom tias nce qib ntawm DHEA thiab DHT hauv cov ntshav thiab cov leeg nqaij ntawm hom 1 mob ntshav qab zib nas. Yog li ntawd, los ntawm nws cov Diosgenin tivthaiv, yam yuav pab kho cov ntshav DHEA, dawb testosterone thiab DHT qib hauv cov neeg ncaws pob.

Tsis lees paub: Cov ntaub ntawv luam tawm ntawm lub vev xaib no los ntawm Is Taws Nem, tsis tau txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm cov ntsiab lus. Thov ua tib zoo saib kom paub qhov txawv. Tsis tas li ntawd, cov khoom muab los ntawm peb lub tuam txhab tsuas yog siv rau kev tshawb fawb tshawb fawb. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv tsis raug.

Yog tias koj txaus siab rau peb cov khoom, lossis muaj cov lus qhia tseem ceeb ntawm peb cov khoom lossis tsis txaus siab rau cov khoom tau txais,

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