Gatifloxacin yog dab tsi?
Gatifloxacin API hmoovyog plaub- tiam fluoroquinolone broad-spectrum antibacterial active pharmaceutical ingredient (API) nrog cov tshuaj formula C₁₉H₂₂FN₃O₄ thiab molecular hnyav ntawm 375.39. Cov khoom no yog dawb los tawm -dawb crystalline hmoov. Nws cov yam ntxwv tshwj xeeb yog pawg methoxy ntawm C-8 txoj haujlwm, kev hloov kho tshuaj lom neeg tshwj xeeb uas txhim kho nws cov tshuaj tua kab mob tiv thaiv kab mob Gram- zoo thiab Gram-negative kab mob. Gatifloxacin tau pom thawj zaug los ntawm Kyorin Pharmaceutical Co., Ltd. hauv Nyij Pooj rau kev kho mob ua pa. Nws cov tshuaj tua kab mob ntawm kev ua haujlwm cuam tshuam nrog inhibiting kab mob DNA gyrase thiab topoisomerase IV, yog li thaiv cov kab mob DNA replication, transcription, thiab kho cov txheej txheem. Qhov API no yog ib qho tseem ceeb hauv kev npaj cov tshuaj tee, ntsiav tshuaj, thiab cov tshuaj txhaj tshuaj.
Gatifloxacin siv nws cov tshuaj tua kab mob hauv cov kab mob ophthalmic thiab kab mob li cas?
Hauv ophthalmology,Gatifloxacin API hmoovyog ib qho tseem ceeb muaj nyob rau hauv qhov muag poob formulations, kho mob siv los kho tus kab mob kab mob conjunctivitis tshwm sim los ntawm cov kab mob uas raug kab mob. Cov kab mob tshwj xeeb uas nws lub hom phiaj suav nrog Gram-positive thiab Gram{2}} kab mob tsis zoo. Hauv kev kho cov kab mob hauv lub cev, gatifloxacin tau siv los kho cov zej zog- kis mob ntsws, mob ua rau mob ntsws ntev, mob sinusitis, kab mob urinary, thiab pyelonephritis, ntawm lwm yam kab mob ua pa thiab tso zis. Tsis tas li ntawd, nyob rau hauv kev tsim tshuaj, cov khoom siv tshuaj no yog ib qho tseem ceeb hauv kev npaj cov ntaub ntawv ntawm qhov ncauj, cov tshuaj hauv cov hlab ntsha, thiab cov tee dej, thiab yog siv dav hauv kev tsim tshuaj generic thiab tsim cov tshuaj tiv thaiv ophthalmic - cov kab mob. Hauv kev tshawb fawb yooj yim, qhov sib xyaw no kuj nquag siv los ua cov cuab yeej siv tshuaj tua kab mob fluoroquinolone, hauv kev tshawb fawb ntawm cov kab mob DNA replication inhibition mechanisms thiab kev ntsuam xyuas cov tshuaj tiv thaiv kab mob.
Yuav siv Gatifloxacin li cas los tsim kom muaj ntau- qib tshuaj tiv thaiv kab mob thiab kab mob bactericidal?
Gatifloxacin API hmoovIb txhij inhibits kev ua ntawm ob lub enzymes tseem ceeb hauv cov kab mob: DNA gyrase thiab topoisomerase IV. Qhov no thaiv cov kab mob DNA replication, transcription, thiab kho cov txheej txheem, tiv thaiv kev loj hlob ntawm cov kab mob pathogenic ntawm nws qhov chaw. Nws nthuav tawm cov kab mob muaj zog tiv thaiv kab mob Gram- cov kab mob zoo, Gram- cov kab mob tsis zoo, qee cov kab mob anaerobes, thiab mycoplasma thiab chlamydia, nrog rau kev tiv thaiv kab mob zoo dua li cov ntaub ntawv nyoos quinolone ua ntej. Cov khoom no yog absorbed sai heev thiab yuav siv tau thaum noj qhov ncauj, topically ntawm lub qhov muag, los yog intravenously. Nws muaj cov ntaub so ntswg muaj zog permeability, tswj cov tshuaj tua kab mob zoo hauv cov ntsws, cov kab mob urinary, thiab cov ntaub so ntswg intraocular. Nws tuaj yeem siv tau ib leeg los ua ib tus neeg sawv cev los tiv thaiv- tus kab mob los yog kev sib xyaw ua ke nrog lwm cov tshuaj tua kab mob txhawm rau txhim kho kev kho mob, ua si qhov tsis muaj txiaj ntsig pharmacological hauv kev kho cov kab mob hauv lub cev thiab cov kab mob hauv cheeb tsam ntawm lub qhov muag.
MF ntawm Gatifloxacin
Cov mis mos molecular: C19H22FN3O4
Molecular Luj: 375.40
Melting Point: 162-166 degree
Kub Point: 587.2 degree
Qhov ceev: 1.36g / cm³
PH: 5.2-7.0
Khoom Specification
| Yam khoom | Specification | Kev tshwm sim |
| Qhov tshwm sim | Dawb rau tawm -dawb crystalline hmoov | Ua raws |
| Kev txheeb xyuas | IR/HPLC raws li tus qauv | Ua raws |
| Assay | 98.5% ~ 101.5% | 99.76% |
| Purity | Ntau dua lossis sib npaug li 99.0% | 99.3% |
| Poob rau ziab | Tsawg dua lossis sib npaug li 0.5% | 0.24% |
| Residue ntawm Ignition | Tsawg dua lossis sib npaug li 0.1% | 0.06% |
| Hnyav Hlau | Tsawg dua lossis sib npaug li 10 ppm | < 5 ppm |
| Xaus | Ua raws li tus qauv kev lag luam | |
Xa koj cov lus nug kom paub meej ntxiv,Nyem email:allen@faithfulbio.comLos yogWhatsApp:+86 13137770562
vim li cas xaiv peb
Peb ua raws li lub hauv paus ntsiab lus ntawm "tus neeg siv khoom ua ntej, kev ua siab ncaj ua ntej", thiab ib txwm muab cov neeg siv khoom nrog cov khoom zoo thiab muaj txiaj ntsig zoo thiab - cov kev pabcuam zoo. Xaiv kev ncaj ncees. Xaiv lub neej noj qab nyob zoo!
Nrog rau peb cov kev siv zog tas mus li thiab kev pabcuam zoo, peb cia siab tias yuav tsim kom muaj kev koom tes ntev - thiab kev loj hlob zoo nrog cov neeg siv khoom thiab muab sijhawm rau peb. Peb ntseeg tias peb yuav txaus siab rau koj nrog thawj -chav kawm zoo, nyab xeeb thiab xa khoom sai thiab txaus siab tom qab- kev muag khoom.
Muaj ntau txoj kev xa khoom rau koj xaiv
| Tsheb thauj mus los | Shipping txoj kev | Cargo hnyav xav tau | Qhov zoo |
| 3-7 hnub | DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, UPS, USPS, FedEx, TNT, EMS |
Haum rau qis dua 50kg. International qhov rooj rau qhov rooj nthuav qhia |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, thiab cov neeg siv khoom hauv Tebchaws Europe thiab Asmeskas tuaj yeem ua tau txaus siab xa khoom ncaj qha los ntawm ob qhov chaw no. |
| 7-15 hnub | Los ntawm Cua | Haum rau ntau tshaj 50kg. ceev thiab pheej yig dua rau kev txiav txim loj |
|
| 15-60 hnub | Los ntawm Hiav Txwv | Haum rau ntau tshaj 500kg. Kev xa khoom pheej yig tshaj plaws |
FAQ:
Q1: Puas yog Gatifloxacin muaj cov tshuaj tua kab mob tseem ceeb tiv thaiv cov tshuaj - cov kab mob resistant?
A1: Nws tuaj yeem thaiv ob qhov tseem ceeb enzymes rau cov kab mob replication, muaj zog inhibitory zog tiv thaiv ntau yam tshuaj -cov tshuaj tiv thaiv Gram- zoo thiab Gram- cov kab mob tsis zoo, muaj cov tshuaj tua kab mob ruaj khov, thiab cov khoom tiav muaj cov kab mob ruaj khov thiab txhim khu kev qha hauv kev kho mob.
Q2: Puas yog Gatifloxacin cov ntaub so ntswg nkag mus tau zoo nrog kev kho qhov muag?
A2: Cov tshuaj muaj kev nkag tau zoo heev thiab tuaj yeem tswj tau cov kab mob tua kab mob zoo hauv cov ntaub so ntswg, kab mob ua pa, thiab cov kab mob tso zis, ua rau nws sib haum nrog ntau yam kev kho mob xws li tshuaj tee qhov muag thiab cov ntsiav tshuaj ntawm qhov ncauj.
Q3: Dab tsi yog qhov pom zoo kom pom zoo thiab pH ntau npaum li cas rau gatifloxacin hauv qhov muag tee?
A3: Qhov pom zoo pom zoo rau qhov muag tee yog 0.3%, nrog rau pH ntau ntawm 5.0-7.2. Peb tuaj yeem muab cov ncauj lus kom ntxaws solubility profiles thiab pH-ruaj khov cov ntaub ntawv nrog cov khoom xa tuaj los pab koj txhim kho koj cov qauv tsim thiab txuag lub sijhawm hauv thawj theem kev txhim kho.
Tsis lees paub: Cov ntaub ntawv luam tawm ntawm lub vev xaib no los ntawm Is Taws Nem, tsis tau txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm cov ntsiab lus. Thov ua tib zoo saib kom paub qhov txawv. Tsis tas li ntawd, cov khoom muab los ntawm peb lub tuam txhab tsuas yog siv rau kev tshawb fawb tshawb fawb. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv tsis raug.
Yog tias koj txaus siab rau peb cov khoom, lossis muaj cov lus qhia tseem ceeb ntawm peb cov khoom lossis tsis txaus siab rau cov khoom tau txais, thov hu rau peb los ntawmEmail: allen@faithfulbio.comLos yogWhatsApp: +86 13137770562. Peb pab neeg tau cog lus los ua kom tiav kev txaus siab ntawm cov neeg siv khoom.
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