Clarithromycin yog dab tsi?
Clarithromycin yog ib tug derivative ntawm erythromycin, ib tug dav-spectrum tshuaj tua kab mob, uas belongs rau macrolide tshuaj tua kab mob. Clarithromycin plays lub luag haujlwm tiv thaiv kab mob feem ntau los ntawm inhibiting synthesis ntawm cov kab mob protein, thiab muaj kev kho mob zoo ntawm qee yam kab mob.
Clarithromycin hmoovyog dawb crystalline hmoov los yog xim tsis muaj koob siv lead ua, tsw thiab iab. Yooj yim soluble hauv chloroform, acetone lossis ethyl acetate, me ntsis soluble hauv ethanol, ether lossis methanol, yuav luag insoluble hauv dej. Cov xim tsis muaj xim zoo li cov muaju tau txais los ntawm chloroform-isopropyl ether (1: 2), nrog rau qhov chaw melting ntawm 217,220 degree (decomposition). Los yog los ntawm ethanol, melting point 222 225 degree . [ ](20, d)-90.4, (c=l, chloroform). UV siab tshaj plaws nqus (chloroform); 288nm (e27. 9).
Clarithromycin muaj cov tshuaj tua kab mob, uas muaj txiaj ntsig zoo rau cov kab mob Gram-positive thiab cov kab mob tsis zoo, thiab tseem muaj cov nyhuv inhibitory ntawm ntau hom penicillin-rhiab heev.
| Khoom npe | Clarithromycin |
| CAS | 81103-11-9 |
| Cov mis mos molecular | C38H69NO13 |
| Molecular hnyav | 747.95 |
| EINECS Number | 1806241-263-5 |
| Kev cia khoom | -20 degree |
| Melting point | 217-220 degree |
| Solubility | Soluble nyob rau hauv dimethyl sulfoxide |
| Qhov tshwm sim |
Dawb hmoov |
| Boiling point | 86 degree |
| Flash(ing) point | 1.1334 (zeeg) |
Dab tsi yog pharmacological kev txiav txim ntawm clarithromycin?
Clarithromycin yog cov tshuaj tua kab mob dav dav ntawm 14 yuan macrolide. Nws cov txheej txheem ntawm kev ua haujlwm yog tib yam li erythromycin, uas feem ntau khi rau cov kab mob 50S ribosome subunit, thiab inhibits cov synthesis ntawm cov kab mob protein los ntawm kev thaiv peptide hloov mus thiab mRNA translocation, yog li ua lub luag haujlwm tiv thaiv kab mob. Piv nrog erythromycin hmoov,clarithromycin hmoovmuaj cov yam ntxwv ntawm kev nqus zoo, lub sijhawm ceev ceev, siab ntshav siab, ntev ib nrab-lub neej thiab tus neeg sib txawv me me. Clarithromycin muaj cov tshuaj tua kab mob muaj zog me ntsis ntawm methicillin-sensitive Staphylococcus thiab Streptococcus dua li erythromycin. Cov tshuaj tua kab mob tiv thaiv kab mob khaub thuas Bacillus yog 2 ~ 4 npaug zog dua erythromycin. Clarithromycin muaj cov nyhuv bacteriostatic ntawm Staphylococcus aureus thiab Streptococcus. Nws muaj cov kab mob bactericidal ntawm pneumococcus thiab kab mob khaub thuas Bacillus. Cov kab mob tshuaj tiv thaiv kab mob tuaj yeem tsim cov enzyme uas methylates RNA thiab methylates qhov chaw ntawm ribosomes, yog li ua rau cov tshuaj tsis tuaj yeem khi rau ribosomes. Hauv vivo tshuaj tua kab mob, cov tshuaj tua kab mob ntawm clarithromycin ntawm Staphylococcus aureus, Streptococcus pyogenes, Pneumococcus thiab Haemophilus influenzae yog 2 ~ 10 npaug zog dua li ntawm erythromycin.
Khoom Specification
| Yam khoom | Specification | Cov txiaj ntsig |
| Kev piav qhia | Dawb los yog yuav luag dawb crystalline hmoov | Ua raws |
| Solubility | Xyaum insoluble hauv dej, Soluble hauv aceto.ne | Ua raws |
| thiab hauv ethylene me ntsis soluble hauv metha.nol. | ||
| Kev txheeb xyuas | Ua raws li claritinomycin RS | Ua raws |
| IR spectrum | ||
| Kev sib hloov tshwj xeeb | Nruab nrab ntawm -89 degree thiab -95 degree | {0}}.0 degree |
| Crystallinity | Ua tau raws li qhov yuav tsum tau ua | Ua tau raws li qhov yuav tsum tau ua |
| pH | Nruab nrab ntawm 7.5 thiab 10.0 | 8.58 |
| Dej | Tsis ntau tshaj 2.0% | 0.64% |
| Residue ntawm ignitions | Tsis ntau tshaj 0.3% | Ua raws |
| Assay | 99.00% | 99.80% |
| Xaus | Ua raws li USP Standard. | |
Kev siv Clarithromycin yog dab tsi?
1.Clarithromycin yog ib qho tshuaj tua kab mob macrolide, uas yog ib qho derivative ntawm erythromycin, thiab clarithromycin tau los ntawm kev hloov OH pawg ntawm 6 txoj hauj lwm ntawm erythromycin A rau OCH3. Nws muaj txiaj ntsig zoo tiv thaiv kab mob gram-zoo thiab tsis zoo, chlamydia thiab mycobacteria, thiab tuaj yeem cuam tshuam yuav luag txhua tus kab mob ua pa.
2. Clarithromycin belongs rau cov tshuaj tua kab mob macrolide, uas yog siv los kho cov kab mob ua pa sab saud thiab qis thiab kab mob ntawm cov nqaij mos subcutaneous.
3. Clarithromycin hmoovtuaj yeem siv ua lwm yam khoom siv raw.
HTML5 atlas ntawm Clarithromycin
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Clarithromycin siv qhov twg?
1.Clarithromycin tuaj yeem siv los kho pharyngitis thiab tonsillitis tshwm sim los ntawm Streptococcus pyogenes.
2. Nws tuaj yeem siv los kho tus mob otitis media, mob hnyav ntawm kev mob ntsws ntev thiab mob ntsws los ntawm cov kab mob rhiab heev.
3. Nws tuaj yeem siv los kho cov kab mob ntawm daim tawv nqaij thiab cov nqaij mos uas tshwm sim los ntawm cov kab mob rhiab heev.
4. Nws tuaj yeem siv los kho tus mob mycoplasma pneumoniae pneumonia, urethritis tshwm sim los ntawm Chlamydia trachomatis thiab nonspecific urethritis.
5. Nws tuaj yeem siv los kho cov kab mob legionnaires.
6. Clarithromycin hmoovKuj tseem siv tau ua ke nrog lwm cov tshuaj los kho Mycobacterium avium kab mob thiab Helicobacter pylori kab mob.
Dab tsi yog qhov txawv ntawm clarithromycin thiab azithromycin?
Qhov sib txawv ntawm clarithromycin thiab azithromycin muaj xws li ntau hom, kev ua tau zoo sib txawv thiab cov khoom sib txawv.
1. Ntau hom:
Azithromycin yog tshuaj tua kab mob macrolide. Clarithromycin yog ib qho tshuaj tua kab mob semi-synthetic macrolide.
2, cov nyhuv txawv:
Azithromycin thiab clarithromycin feem ntau yog siv los kho ntau yam kab mob rhiab heev. Clarithromycin muaj cov txiaj ntsig zoo rau cov kab mob anaerobic, thaum azithromycin muaj txiaj ntsig zoo rau tus kab mob chlamydia.
3. Kev ruaj ntseg khoom sib txawv:
Piv nrog clarithromycin, azithromycin muaj qee qhov kev phiv. Azithromycin tuaj yeem siv rau cov poj niam cev xeeb tub, tab sis clarithromycin tsis tuaj yeem siv rau cov poj niam cev xeeb tub.
Dab tsi yog qhov txawv ntawm amoxicillin thiab clarithromycin?
Amoxicillin thiab clarithromycin yog ob qho tib si tshuaj tua kab mob, tab sis lawv sib txawv hauv kev faib khoom, tshuaj tua kab mob, tshuaj tua kab mob, cov nyhuv tom qab tshuaj tua kab mob thiab cov khoom sib cuam tshuam.
1, kev faib khoom
Amoxicillin yog tshuaj tua kab mob penicillin, thaum clarithromycin yog tshuaj tua kab mob macrolide.
2, antibacterial spectrum
Amoxicillin muaj cov tshuaj tua kab mob zoo tiv thaiv ntau yam kab mob gram-zoo thiab kab mob gram-tsis zoo. Clarithromycin muaj cov tshuaj tua kab mob zoo tiv thaiv ntau yam kab mob gram-zoo thiab kab mob gram-tsis zoo.
3, antibacterial kev ua haujlwm
Cov tshuaj tua kab mob ntawm amoxicillin muaj zog dua li ntawm clarithromycin.
4. Tom qab tshuaj tua kab mob
Amoxicillin feem ntau yog metabolized los ntawm lub raum hauv vivo, thaum clarithromycin feem ntau metabolized los ntawm daim siab hauv vivo, yog li muaj qee qhov sib txawv ntawm cov tshuaj tua kab mob tom qab ntawm ob cov khoom.
5, kev sib txuas ntawm cov khoom
Ob qho amoxicillin thiab clarithromycin tuaj yeem ua rau mob plab hnyuv. Txawm li cas los xij, cov nyhuv inhibitory ntawm amoxicillin ntawm CYP3A4 tsis muaj zog dua li ntawm clarithromycin, yog li amoxicillin thiab clarithromycin feem ntau tsis xav tau cov khoom tshwj xeeb kev sib cuam tshuam.
Kev ceev faj ntawm Clarithromycin hmoov yog dab tsi?
1, lub siab ua haujlwm puas, nruab nrab mus rau lub raum ua haujlwm hnyav nrog ceev faj.
2, kev puas tsuaj loj rau lub raum ua haujlwm, yuav tsum tau hloov kho koob tshuaj.
3. Clarithromycin hmoovyog cross-allergic thiab cross-resistant rau erythromycin thiab lwm yam macrolides.
4. Zoo ib yam li lwm yam tshuaj tua kab mob, kev kis mob hnyav tshwm sim los ntawm cov kab mob fungi lossis cov kab mob tshuaj tiv thaiv yuav tshwm sim. Lub sijhawm no, nws yog ib qho tsim nyog yuav tsum tsis txhob siv Clarithromycin thiab siv cov kev kho mob uas tsim nyog.
5. Hemodialysis lossis peritoneal dialysis tsis tuaj yeem txo cov ntshav plasma concentration ntawm Clarithromycin.
Yuav ua li cas thiab qhov twg yuav Clarithromycin Powder wholesale?
Koj tuaj yeem tso siab rau peb qhov kev txiav txim vim tias peb muaj cov ntaub ntawv zoo ntawm kev muag tshuaj raws cai.
Peb ua qhov kev kuaj xyuas ywj pheej ntawm txhua yam khoom thiab tom qab ntawd muag rau peb cov neeg siv khoom hwm.
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:allen@faithfulbio.comTam sim no.
Muaj ntau txoj kev xa khoom rau koj xaiv
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Tsheb thauj mus los |
Shipping txoj kev |
Cargo hnyav xav tau |
Qhov zoo |
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3-7 hnub |
DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, |
Haum rau qis dua 50kg. |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, |
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7-15 hnub |
Los ntawm Cua |
Haum rau ntau tshaj 50kg. |
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15-60 hnub |
Los ntawm Hiav Txwv |
Haum rau ntau tshaj 500kg. |
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:allen@faithfulbio.comTam sim no.
Tsis lees paub: Cov ntawv luam tawm ntawm lub xaib no yog siv los txhawb kev sib pauv kev kawm thiab kev kawm, thiab tsis txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm nws cov ntsiab lus. Thov lim kom zoo. Yog tias koj ntseeg tias tsab xov xwm no ua txhaum, thov hu rau tus thawj tswj hwm. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv cov ntaub ntawv thiab cov kev pabcuam hauv lub vev xaib no.
Nco tseg: Cov tshuaj no yuav tsum tau siv rau kev tshawb fawb nkaus xwb. Cov lus thov no tsis tau raug soj ntsuam los ntawm Food and Drug Administration. Thov nrog koj tus kws kho mob tham thiab kawm txog cov kev tshawb fawb muaj ua ntej siv lawv. Cov khoom no tsis yog tsim los kuaj xyuas, kho, kho, lossis tiv thaiv txhua yam kab mob.
Cim npe nrov: clarithromycin hmoov cas 81103-11-9, Suav teb, lwm tus neeg, manufacturers, hoobkas, customized, lag luam wholesale, yuav, nqe, tej, ntshiab, tsim, luv nqi, muag, Tshuag, dawb qauv, raw hmoov, raw khoom, ua nyob rau hauv Tuam Tshoj