Minocycline hcl yog dab tsi?
Minocycline hydrochloride yog ib qho tshiab semi-synthetic tetracycline nrog kev ua haujlwm siab, ua haujlwm sai thiab kav ntev. Los ntawm reversibly khi nrog 30S ribosome subunit, nws inhibits protein synthesis ntawm rhiab microorganisms, yog li inhibiting binding ntawm tRNA thiab ribosome, thiab ua tiav cov nyhuv antibacterial. Nws cov tshuaj tua kab mob zoo ib yam li tetracycline. Staphylococcus aureus, Streptococcus thiab Escherichia coli resistant rau tetracycline tseem rhiab heev rau cov khoom no.
Minocycline Hcl hmoovyog daj crystalline hmoov; Tsis muaj ntxhiab tsw; Nws yog hygroscopic. Soluble hauv dej, tsis ruaj khov hauv lub teeb, iab hauv saj, soluble hauv methanol, me ntsis soluble hauv ethanol, thiab yuav luag insoluble hauv ether.
Minocycline hydrochloride yog ib qho hypoxia-inducible factor (HIF-1) inhibitor. Nws kuj muaj kev tiv thaiv kab mob, tiv thaiv kab mob thiab glutamate antagonistic cuam tshuam. Nws kuj tseem tuaj yeem txo cov neurotransmission ntawm glutamate thiab qhia cov khoom tiv thaiv neuroprotective thiab antidepressant teebmeem. Nws inhibits cov synthesis ntawm cov kab mob protein los ntawm kev sib txuas nrog 30S subunit ntawm cov kab mob ribosome, yog li tsim cov nyhuv bacteriostatic.
| Khoom npe | Minocycline hcl |
| CAS | 13614-98-7 |
| Cov mis mos molecular | C23H28ClN3O7 |
| Molecular hnyav | 493.94 |
| EINECS Number | 237-099-7 |
| Kev cia khoom | 2-8 degree |
| Melting point | 205-210 degree (dec) |
| Solubility | Me ntsis soluble hauv dej thiab ethanol (96%). Soluble nyob rau hauv alkali hlau hydroxide thiab carbonate kua. |
| Qhov tshwm sim | Yellow crystalline hmoov |
| Boiling point | 813 degree |
| Flash(ing) point | >110 ° F (230 ° F) |
Minocycline hydrochloride ua haujlwm li cas?
Lub tshuab ntawm minocycline hydrochloride yog tias nws khi rau lub subunit ntawm ribosome 30S, tiv thaiv kev txuas ntxiv ntawm peptide saw, yog li tiv thaiv kev sib txuas ntawm cov protein. Raws li ib tug dav-spectrum tetracycline tshuaj tua kab mob, nws muaj ib tug dav antibacterial spectrum tshaj li cov tshuaj zoo sib xws, thiab muaj ib tug muaj zog inhibitory nyhuv ntawm gram-zoo kab mob xws li tetracycline-resistant Staphylococcus aureus, Streptococcus thiab Neisseria gonorrhoeae nyob rau hauv cov kab mob gram-negative.
Khoom Specification
| Yam khoom | Specification | Cov txiaj ntsig |
| Qhov tshwm sim | Lub teeb daj hmoov, nruab nrab tsw, hygroscopic heev | Ua raws |
| Kev txheeb xyuas | Txuj kev daws teeb meem thiab kev sim tshuaj tib qhov chaw, RF | Ua raws |
| Tshwj xeeb Optical | -2.4 degree ~ -2.8 degree | -2.72 degree |
| Cov hlau hnyav (raws li PB) | Tsawg dua lossis sib npaug li 10ppm | Ua raws |
| Sulfate (SO4) | Tsawg dua lossis sib npaug rau 0.02% | Ua raws |
| Chloride (Cl) | Tsawg dua lossis sib npaug rau 0.02% | Ua raws |
| Phosphate Ion (P) | Tsawg dua lossis sib npaug li 5ppm | Ua raws |
| Residual kuab tshuaj (ethanol) | Tsawg dua lossis sib npaug rau 1.0% | Ua raws |
| pH | 4.5~7.0 | 5.1 |
| Muaj feem xyuam | Spot tsis loj tshaj qhov chaw daws teeb meem | Tsis muaj chaw |
| Cov ntsiab lus dej | Tsawg dua lossis sib npaug li 2% | 0.26% |
| Assay (lub hauv paus qhuav) | 98.0%--102.0% | 99.48% |
| Assay (lub hauv paus qhuav) | 98.5%--100% | 99.20% |
| Xaus | Ua raws li USP Standard. | |
Qhov zoo ntawm Minocycline hydrochloride yog dab tsi?
1.Minocycline Hcl hmoovyog rhiab heev rau Propionibacterium acnes, thiab tua cov kab mob pob txuv kom raug;
2. Cov nyhuv tsis tshwj xeeb los tiv thaiv, ua rau pob txuv liab zoo dua;
3. Kev faib tawm concentration hauv cov qog sebaceous ntawm cov hauv paus plaub hau yog siab, uas tuaj yeem ua lub luag haujlwm tseem ceeb hauv lub cev;
4. Cov tshuaj tiv thaiv tsis zoo yog qhov me me.
HTML5 atlas of Minocycline Hcl
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Minocycline hydrochloride siv qhov twg?
1. Minocycline Hcl yog thawj kab khoom siv rau kev kho pob txuv. Nws yog thawj zaug siv rau kev kho pob txuv los ntawm nws cov nyhuv antibacterial. Tam sim no, ntau thiab ntau cov pov thawj ua pov thawj tias nws cov nyhuv tsis muaj tshuaj tiv thaiv tau ua lub luag haujlwm loj hauv kev txo cov txheej txheem inflammatory ntawm tus kab mob.Minocycline Hcl hmoovindirectly cuam tshuam o los ntawm inhibiting o thiab stimulating kab mob cov khoom.
2. Lub pathogenesis ntawm cov pob txuv ntawm cov kab mob muaj xws li hauv zos vasomotor paj hlwb tsis meej, intradermal telangiectasia, nrog rau cov kab mob uas tsis yog tshwj xeeb inflammatory cell infiltration nyob ib ncig ntawm cov hlab ntsha, thiab ntau cov lymphocytes infiltration nyob ib ncig ntawm sebaceous qog hauv cov hauv paus plaub hau. Minocycline hydrochloride tuaj yeem tsis tsuas yog cuam tshuam qhov mob, tab sis kuj zoo inhibit angiogenesis.
3. Minocycline hydrochloride tuaj yeem kho cov kab mob autoimmune bullous raws li nws cov khoom tiv thaiv. Minocycline hydrochloride muaj tsawg dua qhov tsis zoo tshwm sim ntau dua li kev kho mob glucocorticoid, thiab yog qhov tsim nyog rau cov neeg mob uas muaj contraindications ntawm kev siv glucocorticoid, thiab nws ua ke nrog glucocorticoid tuaj yeem txo nws cov koob tshuaj thiab txo nws lub sijhawm siv.
4. Nws tuaj yeem tiv thaiv melanocytes los ntawm apoptosis induced los ntawm H2O2 hauv vitro, yog li nws tuaj yeem siv los tiv thaiv cov theem ntxov ntawm melanocyte poob hauv vitiligo.
Tsis tas li ntawd, Minocycline hydrochloride yog dav siv los kho cov kab mob urinary xws li syphilis, gonorrhea thiab chlamydia vim nws cov tshuaj tiv thaiv zoo thiab cov kab mob bactericidal.
Dab tsi yog qhov txawv ntawm doxycycline hydrochloride thiab minocycline hydrochloride?
Doxycycline hydrochloride thiab minocycline hydrochloride yog qhov sib txawv rau cov kab mob sib txawv, thiab yuav muaj qee qhov sib txawv hauv kev kho mob. Yog tias nws siv rau cov kab mob hauv plab los ntawm tus kab mob Enterobacteriaceae, doxycycline hydrochloride muaj txiaj ntsig zoo dua, thiab yog tias siv rau cov kab mob ntawm daim tawv nqaij los ntawm tus kab mob staphylococcal, minocycline hydrochloride muaj cov txiaj ntsig zoo dua.
Doxycycline hydrochloride yog tshuaj tua kab mob tetracycline, uas muaj cov nyhuv inhibitory zoo rau cov kab mob kab mob xws li Streptococcus. Yog hais tias tus kab mob no tshwm sim los ntawm tus kab mob ntawm cov kab mob pathogenic microorganisms, cov nyhuv kho ntawm doxycycline hydrochloride yog zoo dua nyob rau lub sij hawm no. Doxycycline hydrochloride hmoov tuaj yeem cuam tshuam kev loj hlob ntawm peptide chains thiab cuam tshuam rau cov synthesis ntawm cov kab mob protein.
Minocycline hydrochloride kuj yog tshuaj tetracycline, uas yog siv los kho cov kab mob ntawm daim tawv nqaij los ntawm Neisseria gonorrhoeae. Lub sijhawm no, cov nyhuv kho ntawm minocycline hydrochloride hmoov zoo dua, uas tuaj yeem cuam tshuam cov protein synthesis ntawm cov kab mob lossis lwm yam kab mob pathogenic microorganisms, yog li ua kom tsis muaj menyuam.
Kev ceev faj ntawm Minocycline hcl hmoov yog dab tsi?
1. Cov tshuaj tiv thaiv kab mob plab, nws raug nquahu kom noj nrog zaub mov.
2. Pseudoencephaloma-like syndrome (tsis txhob siv nrog isotretinoin, retinol lossis vitamin A tib lub sijhawm).
3. Qee zaus kiv taub hau, diplopia, burnout, thiab lwm yam., yuav tsum tsis txhob tsav tsheb, kev khiav hauj lwm cov tshuab txaus ntshai thiab kev ua haujlwm hauv huab cua thaum siv.
4. Photosensitivity, tsis txhob raug tshav ntuj thaum siv.
5. Cov poj niam cev xeeb tub thiab lactating raug txwv.
6. Nws cuam tshuam rau kev loj hlob ntawm cov hniav thiab pob txha, thiab yog txwv tsis pub rau cov menyuam yaus hnub nyoog qis dua 8 xyoo.
Yuav ua li cas thiab qhov twg yuav Minocycline hcl Powder wholesale?
Koj tuaj yeem tso siab rau peb qhov kev txiav txim vim tias peb muaj cov ntaub ntawv zoo ntawm kev muag tshuaj raws cai.
Peb ua qhov kev kuaj xyuas ywj pheej ntawm txhua yam khoom thiab tom qab ntawd muag rau peb cov neeg siv khoom hwm.
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:allen@faithfulbio.comTam sim no.
Muaj ntau txoj kev xa khoom rau koj xaiv
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Tsheb thauj mus los |
Shipping txoj kev |
Cargo hnyav xav tau |
Qhov zoo |
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3-7 hnub |
DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, |
Haum rau qis dua 50kg. |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, |
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7-15 hnub |
Los ntawm Cua |
Haum rau ntau tshaj 50kg. |
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15-60 hnub |
Los ntawm Hiav Txwv |
Haum rau ntau tshaj 500kg. |
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:allen@faithfulbio.comTam sim no.
Tsis lees paub: Cov ntawv luam tawm ntawm lub xaib no yog siv los txhawb kev sib pauv kev kawm thiab kev kawm, thiab tsis txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm nws cov ntsiab lus. Thov lim kom zoo. Yog tias koj ntseeg tias tsab xov xwm no ua txhaum, thov hu rau tus thawj tswj hwm. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv cov ntaub ntawv thiab cov kev pabcuam hauv lub vev xaib no.
Nco tseg: Cov tshuaj no yuav tsum tau siv rau kev tshawb fawb nkaus xwb. Cov lus thov no tsis tau raug soj ntsuam los ntawm Food and Drug Administration. Thov nrog koj tus kws kho mob tham thiab kawm txog cov kev tshawb fawb muaj ua ntej siv lawv. Cov khoom no tsis yog tsim los kuaj xyuas, kho, kho, lossis tiv thaiv txhua yam kab mob.
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