Khoom piav qhia
Hauv cov xwm txheej ambient,Closulon APIyog ib tug dawb los yog faint grey crystalline hmoov. Nws nta zoo physicochemical stability, tiv thaiv deliquescence thiab tawg thaum lub sij hawm warehouses tsis tu ncua, thiab suav raws li ib tug pa sulfonamide zoo tshuaj rau cov tsiaj txhu. Nws lub hom phiaj ntawm kev ua haujlwm ntawm kev txwv cov kab mob parasitic carbonic anhydrase: cuam tshuam cov carbohydrate metabolism thiab lub zog tsim tawm ua rau cov kab mob physiological ua haujlwm ib kauj ruam. Xws li pharmacological zoo tso cai rau nws muaj zog ua haujlwm tiv thaiv lub siab flukes ntawm Fasciola genus, tig nws mus rau hauv ib qho tseem ceeb antiparasitic raw khoom rau kev lag luam nyuj thiab yaj.
Hais txog kev siv scenarios,Closulon APIfeem ntau yog tsim los rau kev lag luam tsiaj yug tsiaj-tshwj xeeb rau ruminants xws li nyuj thiab yaj. Nws ua tau zoo tsis yog tsuas yog tawm tsam cov kab mob loj hlob hauv tus tswv tsev tab sis kuj ua rau pom kev cuam tshuam zoo heev tiv thaiv flukes tsis paub tab uas tseem tsis tau tsim tag nrho; yog li ntawd, nws nquag siv nyob rau hauv pasture-raws li grazing systems. Tshaj li nws thawj daim ntawv thov hauv kev tswj tsiaj nyeg, cov tshuaj no kuj tau siv dav hauv cov chaw tshawb fawb tshawb fawb los tshawb xyuas cov txheej txheem enzymatic ntawm cov cab.
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:sales4@faithfulbio.com
COA
| Cov khoom kuaj | Specification | Kev tshwm sim |
| Kev piav qhia | Dawb kom tawm hmoov dawb | Dawb hmoov |
| Solubility | Me ntsis soluble hauv dej, dawb soluble | Ua raws |
| n acetonitrile thiab hauv methanol, heev | ||
| me ntsis soluble hauv methylene chloride | ||
| Kev txheeb xyuas | A) IR spectrum yog concordant nrog | Ua raws |
| Kev siv spectrum ntawm clorsulon USP RS | Ua raws | |
| B) Lub chromatogram ntawm Assay | Ua raws | |
| npaj tau raws li qhia nyob rau hauv lub | Ua raws | |
| Assay nthuav tawm lub ncov loj rau | Ua raws | |
| clorsulon, lub sijhawm khaws cia uas | Ua raws | |
| sib raug rau qhov Standard | Ua raws | |
| kev npaj tau txais raws li qhia hauv qhov kev xeem | Ua raws | |
| Melting Range | Ntawm 197℃rau 203 degree | 198℃rau 200 degree |
| Poob rau ziab | Tsis ntau tshaj 0.5% w/w | 0.21%w/w |
| Residue ntawm lgnition | Tsis ntau tshaj 0.1% w/w | 0.06%w/w |
| Organic impurities | Analysis 1: Cov chromatogram qhia | Ua raws |
| qhov chaw tseem ceeb ntawm tib tus nqi Re | Tsis pom | |
| Kev Ntsuam Xyuas 2: Txhua tus neeg | Tsis pom | |
| mpurities: (NMT 0.5%); tsis muaj qhov chaw uas tsis yog | Tsis pom | |
| qhov chaw tseem ceeb ntawm cov qauv kev daws teeb meem yog | Tsis pom | |
| arger los yog khaus ntau tshaj qhov uas | Tsis pom | |
| qhov chaw tseem ceeb ntawm 5-uL feem ntawm | Tsis pom | |
| Standard tov B | Tsis pom | |
| Tag nrho impurities: Tsis pub ntau tshaj 2.0% | Tsis pom | |
| Residual solvent test | Methanol: Tsis ntau tshaj 3000 ppm | 22 ppm |
| Assay (Los ntawm HPLC) | 98.0% mus rau 101.0% Nyob rau hauv qhuav | 99.13% |
| Xaus | Ua raws li kev lag luam specification | |
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:sales4@faithfulbio.com
Qhov ceev 1.8 ± 0.1 g / cm³
Boiling Point 651.7 ± 65.0℃ntawm 760 mmHg
Melting Point 194-203 degree
Molecular Formula C₈H₈Cl₃N₃O₄S₂
Molecular Luj: 380.656
Flash Point 348.0 ± 34.3 degree
378.902191
PSA 163.10000
LogP 1.04
Mechanism ntawm Kev Ua ntawm Clorsulon
Targeting Glycolysis Pathway: Severing Energy Supply
Tshwj xeeb tshaj yog lub hom phiaj ntawm lub zog tshwj xeeb metabolic txoj hauv kev ntawm * Fasciola hepatica *, inhibiting glycolytic enzymes tseem ceeb nyob rau hauv parasite los thaiv cov piam thaj metabolism, yog li depleting lub cev lub zog reserves thiab ua rau nws tsis muaj peev xwm ciaj sia.
Competitively Inhibiting Ntau Yam Tseem Ceeb Glycolytic Enzymes
Ua raws li kev sib tw inhibitor, nws lub hom phiaj enzymes xws li phosphoglycerate kinase thiab phosphoglycerate mutase, yog li cuam tshuam qhov kev loj hlob ntawm glycolysis.
Inhibiting Parasite ATP Production thiab txo qis zog
Qhov tseem ceeb txo qis ATP qib hauv cov kab mob fluke, cuam tshuam cov kab mob lub zog homeostasis thiab ua rau poob ntawm cov haujlwm tseem ceeb ntsig txog kev txav mus los, metabolism, thiab kev yug me nyuam.
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:sales4@faithfulbio.com
vim li cas xaiv peb
Peb lub Hoobkas
Pob
Shipping Txoj Kev
|
Tsheb thauj mus los |
Shipping txoj kev |
Cargo hnyav xav tau |
Qhov zoo |
|
3-7 hnub |
DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, |
Haum rau qis dua 50kg. |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, thiab cov neeg muas zaub nyob rau hauv cov teb chaws Europe thiab Amelikas tuaj yeem txaus siab xa cov khoom ncaj qha los ntawm ob qhov chaw no. |
|
7-15 hnub |
Los ntawm Cua |
Haum rau ntau tshaj 50kg. |
|
|
15-60 hnub |
Los ntawm Hiav Txwv |
Haum rau ntau tshaj 500kg. |
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:sales4@faithfulbio.com
FAQ
01. Rau cov tsiaj thiab tej yam kev mob uas yog Clorsulon feem ntau siv?
Nws lub hom phiaj tseem ceeb yog nyuj nyuj, nyuj nyuj, thiab yaj. Nws yog feem ntau siv los kho fascioliasis (mob kab mob siab) thiab nquag tsim ua ke nrog ivermectin ib txhij tshem tawm flukes, nematodes, thiab ectoparasites.
02. Puas muaj tej yam tsis zoo cuam tshuam nrog kev siv Clorsulon?
Cov tsiaj uas muaj kab mob me me feem ntau tsis muaj qhov txawv txav. Txawm li cas los xij, cov nyuj uas muaj kab mob siab ua npaws loj tuaj yeem ua rau lub cev tsis muaj zog, txo qis qab los noj mov, lossis mob plab me me tom qab kho. Cov tsos mob no yog tshwm sim los ntawm cov tshuaj tiv thaiv inflammatory nyob rau hauv lub biliary ib ntsuj av tau tshwm sim los ntawm loj tuag- tawm ntawm parasites thiab feem ntau daws spontaneously.
03. Kuv tuaj yeem yuav Clorsulon API CAS 60200-06-8 qhov twg?
Cim npe nrov: clorsulon api cas 60200-06-8, Tuam Tshoj, lwm tus neeg, manufacturers, hoobkas, customized, lag luam wholesale, yuav, nqe, tej, ntshiab, tsim, luv nqi, muag, Tshuag, dawb qauv, raw hmoov, raw khoom, ua nyob rau hauv Suav teb