Imatinib yog dab tsi?
Imatinib hmoovyog ib qho kev kho qhov ncauj rau qhov mob hnyav, nrawm, thiab mob myelogenous leukemia (CML) rau cov neeg laus nrog Philadelphia chromosome (Ber-Abl) -positive leukemia (CML) tom qab tsis ua haujlwm ntawm kev kho interferon. CML yog kab mob hematopoietic qia cell tshwm sim los ntawm qhov txawv txav DNA ntawm qia hlwb hauv cov pob txha pob txha. DNA abnormalities tsim cov proteins uas txawv txav uas cuam tshuam nrog kev tsim cov qe ntshav dawb hauv cov pob txha, thaum kawg ua rau muaj cov qe ntshav dawb ntau ntxiv. CML tuaj yeem muab faib ua theem ntev, theem nrawm, thiab theem tseem ceeb. Qhov nruab nrab muaj sia nyob ntawm cov neeg mob nyob rau theem tseem ceeb tsuas yog 2-3 lub hlis ntawm lub luj tshib.
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| Imatinib duab | Imatinib MF |
Imatinib hmoov Cov txiaj ntsig
Imatinib hmoovFeem ntau yog siv rau hauv:
Cov neeg sawv cev ntawm qhov ncauj rau kev kho mob ntawm cov neeg laus laus nrog Philadelphia chromosome (Ber-Abl) - cov kab mob myelogenous leukemia nyob rau hauv cov mob hnyav, nrawm, thiab mob ntev tom qab ua tsis tiav ntawm kev kho interferon.
Kev siv ntawm Imatinib
Hauv vitro inhibition ntawm ib pawg ntawm tyrosine thiab txhob lo lo ntxhuav / threonine protein kinases pom tau tias Imatinib zoo inhibited V-ABL tyrosine kinase thiab PDGFR nrog IC50 ntawm 0.6 thiab 0.1μM feem. . Imatinib inhibits tus kheej-dependent activation ntawm qus-hom C-kit kinase kev ua si nrog ib tug IC50 ntawm txog 0.1μM, zoo ib yam li cov concentration xav tau rau PDGFR inhibition. Imatinib inhibited kev loj hlob ntawm tib neeg bronchial cancer cell NCI-H727 thiab pancreatic cancer cell BON -1 nrog IC50 ntawm 32.4 thiab 32.8μM, raws li. Cov kev tshawb fawb tsis ntev los no tau pom tias Imatinib muaj peev xwm rov qab kho nws cov tshuaj tiv thaiv kab mob qog ntshav qab zib los ntawm kev tswj hwm hERG1K (ntxiv rau) channel, uas tau nthuav tawm ntau hauv cov hlwb leukemia thiab ua rau mob ntshav qab zib.
Yam khoom
Nilotinib | 641571-10-0 |
Imatinib | 152459-95-5 |
Lapatinib | 231277-92-2 |
Lapatinib Ditosylate | 388082-78-8 |
Toremifene Citrate | 89778-27-8 |
Sodium dichloroacetate hmoov | 2156-56-1 |
Ribonucleic acid | 63231-63-0 |
sorafenib tosylate | 475207-59-1 |
Dacarbazine | 4342-03-4 |
Vincristine sulfate | 2068-78-2 |
Vinorelbine Tartrate | 125317-39-7 |
Vinorelbine | 71486-22-1 |
Vinblastine | 865-21-4 |
Vinblastine Sulfate / Vinblastine Sulphate | 143-67-9 |
vincristine | 57-22-7 |
Carmustine | 154-93-8 |
Combretastatin A -4 | 117048-59-6 |
Mitomycin C | 50-07-7 |
Topotecan | 123948-87-8 |
Yuav Ua Li Cas Tau Txais Cov Qauv ntawmImatinib?
Txais tos kom xa ib qho kev nug rausunny@faithfulbio.comtxhua lub sijhawm rau tus qauv dawb yog tias koj xav tau API hmoov Imatinib.
Qhov zoo tshaj plaws Imatinib Chaw tsim tshuaj paus thiab tsum
Faithfulbio muaj kev paub dhau los hauv kev xa tawm cov ntaub ntawv raw thiab tau tsim kev sib raug zoo thiab kev koom tes ntev nrog peb cov neeg siv khoom. Peb ib txwm muab cov khoom zoo thiab kev pabcuam ua ntej. Yog tias koj muaj cov khoom siv raw khoom xav tau, thov hu rau peb. Peb tuaj yeem lees paub qhov kev txiav txim nrog koj raws li koj qhov yuav khoom ntau. Peb kuj txhawb peb txoj kev koom tes thawj zaug pib los ntawm cov qauv. Tsis tas li ntawd, peb txoj kev thauj mus los sai thiab nyab xeeb kuj ua rau koj tshem tawm cov teeb meem ntawm kev lis kev cai.
Peb muaj kev ntseeg siab ntawm peb cov khoom zoo, tab sis yog tias muaj teeb meem tom qab muag, peb yuav teb sai li sai tau thiab daws lawv nrog koj txoj hauv kev zoo tshaj plaws.
Vim Li Cas Xaiv Faithfulbio Imatinib?
Faithfulbio tshwj xeeb hauv Imatinib tau ntau xyoo, peb muab cov khoom lag luam ntawm tus nqi sib tw, thiab peb cov khoom yog qhov zoo tshaj plaws, vim tias peb nruj heev hauv cov khoom tsim thiab kev sim, thiab muaj kev ua tiav thiab kev loj hlob. Tsis tas li ntawd, peb cov neeg ua haujlwm Cov lus hais rau cov khoom muaj kev sib tw heev.
Muaj ntau txoj kev xa khoom rau koj xaiv
Sijhawm thauj mus los | Shipping txoj kev | Cargo hnyav xav tau | Qhov zoo |
3-7 hnub | DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, | Haum rau qis dua 50kg. | Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, lub teb chaws USA, |
7-15 hnub | Los ntawm Cua | Haum rau ntau tshaj 50kg. | |
15-60 hnub | Los ntawm Hiav Txwv | Haum rau ntau tshaj 500kg. |
Muaj ntau txoj kev them nyiaj rau koj xaiv
Cov nqe lus them nqi | Tuam txhab txhab nyiaj hloov tsheb (European accounts, American accounts) |
Daim npav rho nyiaj (VISA / Master) | |
Western Union | |
MoneyGram | |
Paypal | |
Alipay | |
WeChat them |
ua siab zoo ceeb toom:Siv cov khoom sib xyaw no rau kev tshawb fawb nkaus xwb. Tag nrho cov tebchaw muaj kev pheej hmoo. Thov nrog koj tus kws kho mob tham thiab kawm txog cov kev tshawb fawb muaj ua ntej siv. Tsis tas li ntawd, cov lus piav qhia saum toj no ntawm qhov sib xyaw yog los ntawm cov ntaub ntawv online. Yog tias muaj kev ua txhaum cai, thov hu rau peb kom tshem tawm.
Qhov twg Yuav Nilotinib hmoov?
Cia li xa email rausunny@faithfulbio.com, lossis xa koj qhov yuav tsum tau ua hauv daim ntawv hauv qab, peb muaj kev pabcuam txhua lub sijhawm!
Cim npe nrov: imatinib hmoov cas 152459-95-5, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, ntshiab, tsim, kev muag khoom