Loperamide hcl yog dab tsi?
Loperamide Hcl hmoovyog cov hmoov dawb mus rau yuav luag dawb, yuav luag tsis muaj ntxhiab. Nws yog hydrochloride ntawm cov organic amine, me ntsis soluble hauv dej tab sis yooj yim soluble hauv glacial acetic acid, ethanol thiab methanol. Loperamide Hcl yog ib hom tshuaj uas nquag siv los ua cov tshuaj tiv thaiv kab mob ntev ntev, uas tuaj yeem siv los tswj cov tsos mob ntawm tus mob plab thiab mob ntev. Tsis tas li ntawd, cov khoom lag luam molecule kuj tseem siv tau rau cov neeg mob ileostomy kom txo tau cov nqi thiab zaus ntawm cov plab hnyuv siab raum thiab nce qhov sib xws thiab tawv ntawm cov quav.
Loperamide hydrochloride kuj yog ib qho kev xaiv sib tw tib neeg txoj hnyuv carboxylesterase (hiCE) inhibitor. Loperamide hcl muaj cov nyhuv antidiarrheal.
Loperamide hcl tuaj yeem tiv thaiv kev sib kis ntawm txoj hnyuv du thiab txo txoj hnyuv peristalsis. Nws tseem tuaj yeem txo qhov tso tawm ntawm acetylcholine los ntawm txoj hnyuv phab ntsa ntawm cov hlab ntsha, thiab ncaj qha inhibit peristaltic reflexes los ntawm kev sib cuam tshuam hauv zos ntawm cholinergic thiab non-cholinergic neurons. Loperamide hcl tuaj yeem ua kom ntev lub sijhawm nyob ntawm cov zaub mov hauv cov hnyuv me, txhawb kev nqus dej, electrolytes thiab qabzib, thiab inhibit plab hnyuv hypersecretion los ntawm prostaglandins, cholera toxin thiab lwm yam enterotoxins.
| Khoom npe | Loperamide hydrochloride |
| CAS | 34552-83-5 |
| Cov mis mos molecular | C29H34Cl2N2O2 |
| Molecular hnyav | 513.5 |
| EINECS Number | 252-082-4 |
| Kev cia khoom | 2-8 degree |
| Melting point | 223-225 degree |
| Solubility | Me ntsis soluble hauv dej, yooj yim soluble hauv ethanol (96%) thiab methanol. |
| Qhov tshwm sim | Dawb rau ze li ntawm cov hmoov dawb |
| Acidity coefficient (pKa) | 8.66 (ntawm 25 degree) |
| Qhov ntom | 1.1905 (zeeg) |
Yuav ua li cas yog lub pharmacological mechanism ntawm Loperamide Hcl?
1. Loperamide Hcl ua rau opioid receptors nyob rau hauv plab hnyuv phab ntsa los tiv thaiv kev tso tawm ntawm acetylcholine thiab prostaglandin, yog li inhibiting plab hnyuv peristalsis thiab prolonging lub sij hawm tuav ntawm cov hnyuv.
2. Loperamide Hcl tuaj yeem ua rau qhov nro ntawm qhov quav sphincter, yog li nws tuaj yeem cuam tshuam fecal incontinence thiab ceev ceev, thiab tseem tuaj yeem siv rau cov neeg mob uas tau phais anorectal.
3. Loperamide Hcl muaj kev sib raug zoo nrog cov kab mob hauv plab hnyuv thiab pom tseeb "thawj-dhau metabolism", uas ua rau nws tsis yooj yim rau cov ntshav ncig.
Khoom Specification
| Yam khoom | Specification | Cov txiaj ntsig |
| Cov cim | Dawb mus rau dawb crystalline hmoov nrog cov yam ntxwv zoo li sulfide ordor | Ua raws |
| Kev txheeb xyuas | IR: zoo ib yam li Reference Standard | Ua raws |
| Kev sib hloov tshwj xeeb | -127 degree rau -132 degree | -131 degree |
| Poob rau ziab | Tsawg dua lossis sib npaug rau 0.5% | 0.06% |
| Sulfated tshauv | Tsawg dua lossis sib npaug rau 0.2% | 0.03% |
| Cov hlau hnyav | Tsawg dua lossis sib npaug rau 0.002% | Ua raws |
| pH | 2.0 rau 2.6 | 2.3 |
| Related Compouds | 1.Single Impurity Tsawg dua lossis sib npaug rau 1.0% | Tsis pom |
| 2.Sum of Impurity Tsawg dua lossis sib npaug rau 2.0% | Tsis pom | |
| Kev ntsuam xyuas (Anhydrous) | 98. 0% rau 101.5% | 100.20% |
| Xaus: | Raws li Enterprise Specification. | |
Loperamide Hcl ua dab tsi?
Loperamide Hcl hmoovinhibits plab hnyuv motility thiab nres raws plab los ntawm stimulating lub enteric paj hlwb-opioid receptors.
1. Antidiarrheal nyhuv
Loperamide Hcl tuaj yeem xaiv ua kom lub paj hlwb enteric-opioid receptors, txo cov hnyuv motility thiab secretion, thiab ua lub luag haujlwm tiv thaiv kab mob. Cov khoom no tuaj yeem ua rau lub sijhawm ntev ntawm cov khoom siv hauv plab, txo qis kev ua haujlwm ntawm cov hnyuv me, thiab thim rov qab tso tawm ntawm acetylcholine los ntawm cov hlab ntsha, yog li ua rau tsis muaj zog hauv zos cov tshuaj tiv thaiv kab mob raws plab xws li cov zaub mov seem rau cov receptors ntawm lub plab hnyuv. .
2. Txo lub plab zom mov
Kev siv Loperamide Hcl tuaj yeem txo qhov ntim thiab ntev ntawm lub plab thiab duodenum, yog li txo qis kev nkag mus sai ntawm cov zaub mov nkag mus rau hauv cov hnyuv me, uas yuav pab txo qis cov tsos mob xeev siab thiab ntuav. Tsis tas li ntawd, nws tuaj yeem txhawb kev tso tawm ntawm somatostatin los ntawm hypothalamus, uas yuav ua rau qeeb qeeb ntawm lub plab zom mov thiab ua rau muaj kev tawm tsam ntawm ileocecal valve.
3. Txhim kho qhov mob plab
Loperamide Hcl muaj cov txiaj ntsig ntawm kev txo cov leeg nqaij leeg, yog li nws muaj kev kho mob zoo rau cov tsos mob plab tsis zoo tshwm sim los ntawm kev ua tsis zoo ntawm plab hnyuv. Tsis tas li ntawd, nws tseem tuaj yeem ua tiav lub hom phiaj ntawm sedation thiab pw tsaug zog los ntawm kev ua haujlwm ncaj qha rau hauv nruab nrab paj hlwb, yog li pab tswj kev pw tsaug zog.
4. Ua kom qab los noj mov
Kev cem quav yuav tshwm sim tom qab siv loperamide hydrochloride. Nyob rau lub sijhawm no, lub cev feem ntau muaj reflex nce hauv qab los noj mov txhawm rau tshem tawm cov khoom khaws cia no.
5. Tswj cov electrolyte tshuav nyiaj li cas
Thaum muaj mob raws plab, nquag plob tsis so tswj yuav ua rau poob dej thiab electrolytes ntau dhau, ua rau lub cev qhuav dej thiab electrolyte tsis txaus. Kev siv Loperamide Hcl tuaj yeem pab ua kom lub plab zom mov ib txwm ua haujlwm ntawm lub cev los ntawm nws cov tshuaj tiv thaiv kab mob, yog li tiv thaiv tsis ncaj los yog kho cov dej thiab electrolyte tsis txaus los ntawm raws plab.
HTML5 atlas of Loperamide Hcl
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Kev ceev faj ntawm Loperamide Hcl yog dab tsi?
1. Rau kev mob raws plab nrog kab mob plab hnyuv, yuav tsum siv cov tshuaj tua kab mob zoo tib lub sijhawm.
2. Nws yuav tsum tsis txhob siv rau cov neeg mob uas xav tau kom tsis txhob muaj kev cuam tshuam ntawm txoj hnyuv, tshwj xeeb tshaj yog cov neeg uas muaj plab hnyuv, plab plab lossis cem quav.
3. Cov neeg mob raws plab feem ntau poob dej thiab electrolytes, thiab dej thiab electrolytes yuav tsum tau ntxiv kom tsim nyog.
4. Loperamide Hcl yog metabolized tag nrho los ntawm daim siab; Cov neeg mob uas muaj lub siab ua haujlwm tsis zoo tuaj yeem raug kev txom nyem los ntawm kev noj tshuaj ntau dhau ntawm cov tshuaj hauv lub cev, thiab kev saib xyuas yuav tsum tau them nyiaj rau hauv nruab nrab cov paj hlwb lom tshuaj lom.
Yuav ua li cas thiab qhov twg yuav Loperamide Hcl Powder wholesale?
Koj tuaj yeem tso siab rau peb qhov kev txiav txim vim tias peb muaj cov ntaub ntawv zoo ntawm kev muag tshuaj qhia kev cai lij choj.
Peb ua qhov kev kuaj xyuas ywj pheej ntawm txhua yam khoom thiab tom qab ntawd muag rau peb cov neeg siv khoom hwm.
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:allen@faithfulbio.comTam sim no.
Muaj ntau txoj kev xa khoom rau koj xaiv
|
Tsheb thauj mus los |
Shipping txoj kev |
Cargo hnyav xav tau |
Qhov zoo |
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3-7 hnub |
DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, |
Haum rau qis dua 50kg. |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, |
|
7-15 hnub |
Los ntawm Cua |
Haum rau ntau tshaj 50kg. |
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15-60 hnub |
Los ntawm Hiav Txwv |
Haum rau ntau tshaj 500kg. |
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:allen@faithfulbio.comTam sim no.
Tsis lees paub: Cov ntawv luam tawm ntawm lub xaib no yog siv los txhawb kev sib pauv kev kawm thiab kev kawm, thiab tsis txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm nws cov ntsiab lus. Thov lim kom zoo. Yog tias koj ntseeg tias tsab xov xwm no ua txhaum, thov hu rau tus thawj tswj hwm. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv cov ntaub ntawv thiab cov kev pabcuam hauv lub vev xaib no.
Nco tseg: Cov tshuaj no yuav tsum tau siv rau kev tshawb fawb nkaus xwb. Cov lus thov no tsis tau raug soj ntsuam los ntawm Food and Drug Administration. Thov nrog koj tus kws kho mob tham thiab kawm txog cov kev tshawb fawb muaj ua ntej siv lawv. Cov khoom no tsis yog tsim los kuaj xyuas, kho, kho, lossis tiv thaiv txhua yam kab mob.
Cim npe nrov: loperamide hcl hmoov cas 34552-83-5, Tuam Tshoj, lwm tus neeg, manufacturers, hoobkas, customized, lag luam wholesale, yuav, nqe, tej, ntshiab, tsim, luv nqi, kev muag, Tshuag, dawb qauv, raw hmoov, raw khoom, ua hauv Suav teb