Pyrimethamine hmoov CAS 58-14-0

Pyrimethamine tuaj yeem inhibit dihydrofolate reductase, yog li ntawd dihydrofolate tsis tuaj yeem hloov mus rau hauv tetrahydrofolate, uas ua rau txo cov nucleic acid synthesis thiab inhibition ntawm kev loj hlob ntawm plasmodium. Nws yog siv los tiv thaiv malaria, thiab tseem tuaj yeem ua ke nrog primaquine los tiv thaiv malaria rov tshwm sim. NtshiabPyrimethamine hmoovyog dawb crystal, tsw thiab tasteless. Insoluble hauv dej, me ntsis soluble hauv ethanol, chloroform, acetone, soluble hauv dilute ntxhia acid. Lub melting point yog 232 ~ 235 degree.

Pyrimethamine thiab Sulfadiazine puas tuaj yeem siv ua ke?

Ob qho tshuaj muaj tshuaj tiv thaiv kab mob malarial. Lawv tsis tsuas muaj cov qauv tshuaj zoo sib xws, tab sis kuj tuaj yeem cuam tshuam rau cov metabolism hauv folate, ua rau inhibition ntawm pob txha pob txha hematopoietic muaj nuj nqi thiab ua rau muaj kev phiv xws li leukopenia thiab thrombocytopenia. Tsis tas li ntawd, nws yuav ua rau muaj kev pheej hmoo ntawm kev tsim megaloblastic anemia. Yog li ntawd, nws tsis pom zoo kom siv ob qho tib si ua ke.
Thaum siv Pyrimethamine, yuav tsum tau ua tib zoo saib xyuas cov kab mob hematological kom tsis txhob muaj ntshav qab zib lossis lwm yam kab mob hauv cov ntshav. Txawm li cas los xij, Sulfadiazine yuav tsum tau ceev faj txog qhov muaj peev xwm nephrotoxicity txaus ntshai, tshwj xeeb tshaj yog rau cov neeg uas muaj keeb kwm muaj kab mob raum.

Peb lub tuam txhab tuaj yeem muab Pyrimethamine thiab Sulfadiazine ntawm tus nqi tsim nyog. Yog tias koj txaus siab, thov hu rau kuv ntawmemail:sales6@faithfulbio.com

Cov tshuaj pharmacological ntawm cov khoom no yog dab tsi?

Pyrimethamine yog cov khoom siv los tiv thaiv malaria, uas ua haujlwm los ntawm inhibiting dihydrofolate reductase, cuam tshuam rau kev siv tetrahydrofolate, txo cov nucleic acid synthesis, thiab yog li inhibiting malaria parasite reproduction. Txawm hais tias nws tsis muaj qhov cuam tshuam tseem ceeb rau gametophytes ntawm cov kab mob malaria, cov tshuaj uas muaj cov ntshav nkag mus rau hauv lub cev yoov tshaj cum tuaj yeem cuam tshuam kev loj hlob ntawm gametophytes hauv lub cev yoov tshaj cum, yog li thaiv kev sib kis. Tib lub sijhawm,Pyrimethamine hmoovthiab chloroquine muaj kev tiv thaiv ntawm placental pathological hloov tom qab tus kab mob malaria los ntawm kev txo cov oxidative kev nyuaj siab thiab cell apoptosis qib. Lawv kuj tuaj yeem txo qhov feem pua ​​​​ntawm cov qe ntshav liab uas muaj kab mob hauv cov ntshav, yog li ua tiav cov txiaj ntsig zoo ntawm malaria. Tsis tas li ntawd, Pyrimethamine tuaj yeem siv tsis tau tsuas yog rau kev kho mob toxoplasmosis, tab sis kuj rau kev cog qoob loo ntawm cov khoom hauv dej, uas tuaj yeem txhim kho cov kab mob ntawm cov ntses hauv dej.Tab sis, cov kev mob tshwm sim ntawm Pyrimethamine yog qhov tseem ceeb, thiab kev siv ntau dhau tuaj yeem ua rau cov kab mob tsis zoo. kev tsim tawm ntawm cov tsiaj nyeg thiab nqaij qaib, thiab nws tsis yooj yim kom rov zoo.

Peb yuav tsum xyuam xim rau dab tsi thaum siv nws?

Raws li kuv tau hais los saum toj no, pyrimethamine yog cov tshuaj kho tsiaj dav dav siv dav hauv cov kab mob antigen, feem ntau yog siv rau kev tiv thaiv malaria thiab kev tiv thaiv kev rov tshwm sim hauv lub sijhawm so. Tshwj xeeb tshaj yog rau plasmodium falciparum thiab plasmodium vivax, thiab nws cov txiaj ntsig tiv thaiv tuaj yeem kav ntev tshaj li ib lub lim tiam vim nws qhov tso tawm qeeb. Nws yog ib qho tshuaj tiv thaiv etiological zoo heev. Txawm li cas los xij, cov teeb meem tsis zoo ntawm cov khoom no kuj pom tseeb. Cov tshuaj toxicity ntawm pyrimethamine yog tsawg heev thiab kuj muaj kev nyab xeeb thaum nws tau noj hauv qhov ncauj dav dav siv tshuaj tiv thaiv kab mob, tab sis nws yuav cuam tshuam nrog kev siv folic acid hauv lub cev thaum nws siv ntau npaum li cas, xws li noj 25mg txhua hnub rau ntau tshaj. ib hlis, thiab yuav muaj folic acid deficiency, uas yuav ua rau megaloblastic anemia. Tsis tas li ntawd, nws muaj peev xwm ua kom muaj txiaj ntsig zoo hauv cov khoom siv dej, dhau ntawm qhov ntau, tib neeg yuav ua rau hemolytic anemia tom qab noj mov, thiab txawm tias muaj kev cuam tshuam ncaj qha rau hauv nruab nrab paj hlwb. Yog tias koj noj ntau ntau rau lub sijhawm ntev lossis sijhawm luv, koj yuav tsis tsuas muaj cov tsos mob lom lom, tab sis kuj tseem muaj qhov cuam tshuam tsis zoo rau cov ntaub so ntswg uas loj hlob thiab tsim tawm sai heev, xws li pob txha pob txha thiab plab hnyuv mucosa, ua rau muaj kev puas tsuaj rau hematopoietic kev ua haujlwm lossis ua rau lub plab zom mov thiab ua rau muaj kev hloov pauv ntawm saj, mob tus nplaig, liab, kub hnyiab thiab lwm yam.

Yog li ntawd, peb yuav tsum siv raws li tus kws kho mob cov lus qhia, tab sis peb yuav tsum tau xyuam xim rau cov xwm txheej hauv qab no thiab xyuas thiab mus ntsib kws kho mob sai li sai tau:
1. Yog hais tias qaug zog, xeev siab, ntuav, mob plab, kub taub hau, cyanosis, jaundice, splenomegaly thiab lwm yam tsos mob lom lom tshwm sim tom qab noj cov tshuaj, tsis txhob noj cov tshuaj raws sij hawm, thiab tam sim ntawd ua plab hnyuv, hloov dej thiab lwm yam kev kho mob.
2. Vim tias qhov saj no qab zib, cov menyuam yaus yuav tsum raug tshuaj lom los ntawm qhov yuam kev thiab yuav tsum tau saib xyuas tshwj xeeb rau kev khaws cia.
3. Kev siv sijhawm ntev tuaj yeem cuam tshuam nrog kev siv folic acid hauv lub cev, thiab megaloblastic anemia yuav tshwm sim. Lub sijhawm no, peb yuav tsum kuaj xyuas cov ntshav tsis tu ncua thiab kho nws nrog calcium foryltetrahydrofolate tom qab nws tshwm sim.

Peb nkag siab li cas kev siv ua ke ntawm cov khoom no?

Vim nws cov nyhuv ntawm cov theem infrared ntawm cov kab mob malaria, nws feem ntau siv ua ke nrog Primaquine los tiv thaiv kev rov tshwm sim.
Ua ke nrog dihydrofolate synthase inhibitors (xws li Sulfamethoxypyridazine lossis 4,4'-Diaminodiphenylsulfone), nws tuaj yeem ua ob npaug thaiv cov folate metabolism ntawm cov kab mob malaria thiab txhim kho lawv cov txiaj ntsig, ncua lossis tiv thaiv kev tshwm sim ntawm cov tshuaj tiv thaiv kab mob.
Tsis tuaj yeem siv ua ke nrog lwm cov dihydrofolate reductase inhibitors vim nws tuaj yeem txhim kho toxicity.

Muaj ntau txoj kev xa khoom rau koj xaiv

Peb lub zog:

Peb lub tuam txhab tau dhau los ntawm FDA thiab ISO19001 kev tswj hwm qhov system ntawv pov thawj. Thiab peb muaj kev koom tes nrog kev cog lus nrog ntau lub chaw tsim khoom thiab chaw soj nstuam hauv Suav teb, Peb lub tuam txhab tuaj yeem muab cov khoom lag luam hais hauv tsab xov xwm no ntawm tus nqi zoo dua, xws li Pyrimethamine, Sulfadiazine, Primaquine, Sulfamethoxypyridazine, 4,4'-Diaminodiphenylsulfone, CHLOROQUINE, L- Tetrahydrofolic Acid thiab lwm yam. Yog tias koj txaus siab, thov sau ib tsab ntawv.

Peb tsis tsuas yog muaj qhov tshwj xeeb zoo hauv kev thauj mus los, tab sis kuj txhawb ntau txoj kev them nyiaj, txawm tias koj siv nyiaj US, euros, Australian las, lossis cov nyiaj hauv zos los ntawm Singapore, Malaysia, Thaib, thiab lwm yam. Peb kuj tuaj yeem txhawb cov txiaj ntsig hauv zos hauv cov cheeb tsam thiab cov tebchaws no. Tsis tas li ntawd, peb kuj txhawb nqa cov npav hauv txhab nyiaj (credit cards, thiab lwm yam) rau kev them nyiaj.

Tsis lees paub: Cov ntaub ntawv luam tawm ntawm lub vev xaib no los ntawm Is Taws Nem, tsis tau txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm cov ntsiab lus. Thov ua tib zoo saib kom paub qhov txawv. Tsis tas li ntawd, cov khoom muab los ntawm peb lub tuam txhab tsuas yog siv rau kev tshawb fawb tshawb fawb. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv tsis raug.

Yog tias koj txaus siab rau peb cov khoom, lossis muaj cov lus qhia tseem ceeb ntawm peb cov khoom lossis tsis txaus siab rau cov khoom tau txais, thov hu rau peb los ntawmEmail :sales6@faithfulbio.com  . Peb pab neeg tau cog lus los ua kom tiav kev txaus siab ntawm cov neeg siv khoom.

Cim npe nrov: pyrimethamine hmoov cas 58-14-0, Suav teb, lwm tus neeg, manufacturers, hoobkas, customized, lag luam wholesale, yuav, nqe, tej, ntshiab, tsim, luv nqi, muag, Tshuag, dawb qauv, raw hmoov, raw khoom, ua nyob rau hauv Tuam Tshoj