SB 242084 dihydrochloride yog dab tsi?
SB 242084 dihydrochloride hmoovyog 5-HT2C receptor antagonist nrog kev xaiv, kev sib tw, thiab kev sib raug zoo siab (pKi=9.0), uas tuaj yeem nkag mus rau hauv cov ntshav-hlwb barrier. Nws nthuav tawm 158 quav thiab 100 quav xaiv ntawm 5-HT2A thiab 5-HT2B receptors hauv vitro, raws li, thiab tuaj yeem ua rau muaj kev ua haujlwm ntawm dopaminergic neurons hauv ventral tegmental cheeb tsam (VTA) ntawm midbrain thiab dopamine tso tawm hauv nucleus vivo. Nws kuj tseem tuaj yeem txhim kho mitochondrial noob qhia thiab oxidative metabolism los ntawm 5-HT2A receptors. Cov khoom no muaj peev xwm tshawb fawb zoo hauv cov tsos mob tsis zoo ntawm kev ntxhov siab, kev nyuaj siab, thiab tus mob schizophrenia, nrog rau kev puas tsuaj rau lub cev.
Nws yuav tsum raug sau tseg tias cov khoom no tsis yog muag rau tib neeg thiab tsuas yog siv rau kev tshawb fawb txog kev tshawb fawb. Nws tsis yog npaj rau kev sim tib neeg lossis kev sim tsiaj tsis yog kev tshawb fawb.
| Khoom npe | SB 242084 dihydrochloride hmoov |
| CAS | 1049747-87-6 |
| Cov mis mos molecular | C21H21Cl3N4O2 |
| Molecular hnyav | 467.77604 |
| EINECS Number | NA |
| melting point | NA |
| solubility | NA |
| Cia tej yam kev mob | Muab kaw rau hauv qhuav, Chav Kub |
| Qhov tshwm sim | hmoov dawb |
| kub point | NA |
| Qhov ntom | NA |
SB 242084 dihydrochloride ua li cas?
Txoj kev tsim khoom ntawmSB 242084 dihydrochloride hmoovyog raws li nram no:
Synthesis txoj kev ib: Ntxiv 25ml ntawm DCM nyob rau hauv nitrogen rau ib tug nplaim qhuav puag ncig hauv qab khob. Tom qab 3 teev, saib xyuas cov tshuaj tiv thaiv sib tov siv nyias - txheej chromatography kom txog thaum cov khoom siv raw tau noj tag. Ntxiv cov tshuaj diluted (10ml, 0.1M) rau qhov sib tov.
Nws yuav tsum raug sau tseg tias cov ntaub ntawv no yuav tsis ua tiav, thiab cov txheej txheem tsim khoom tiag tiag yuav koom nrog ntau cov kauj ruam thiab cov xwm txheej. Thaum tsim cov khoom siv tshuaj lom neeg, cov cai tswj kev nyab xeeb thiab kev cai lij choj yuav tsum tau ua raws li nruj me ntsis.
Khoom Specification
| Yam khoom | Specification | Cov txiaj ntsig |
| Purity | Ntau dua lossis sib npaug li 99% | 99.75% |
| Qhov tshwm sim | Dawb hmoov | Ua raws |
| Xim | Ua raws | Ua raws |
| tsw & saj | Yam ntxwv | Ua raws |
| Kev txheeb xyuas | Qhov zoo | Ua raws |
| Poob rau ziab | Tsawg dua lossis sib npaug li 1.0% | 0.22% |
| Residue ntawm ignition | Tsawg dua lossis sib npaug li 0.5% | 0.14% |
| Xaus | Ua raws li kev lag luam specification | |
SB 242084 dihydrochloride feem ntau siv nyob qhov twg?
SB 242084 dihydrochloride hmoovyog ib qho kev xaiv, kev sib tw, thiab kev sib raug zoo siab 5-HT2C receptor antagonist nrog cov ntaub ntawv tshawb fawb hauv qab no:
Kev tshawb fawb txog Neuroscience: Nws tuaj yeem ua kom cov haujlwm tseem ceeb ntawm dopaminergic neurons nyob rau hauv ventral tegmental cheeb tsam (VTA) ntawm midbrain thiab tso tawm ntawm dopamine nyob rau hauv lub nucleus accumbens. Yog li, nws muaj txiaj ntsig zoo hauv kev kawm txog kev ua haujlwm basal thiab dopamine tso tawm ntawm dopaminergic neurons.
Kev tshawb fawb ntawm mitochondrial gene qhia thiab oxidative metabolism: Nws tuaj yeem ua rau cov mitochondrial noob qhia thiab oxidative metabolism los ntawm 5-HT2A receptors, yog li muaj peev xwm siv tau hauv cov kev tshawb fawb ntsig txog.
Kev tshawb fawb txog kev puas siab puas ntsws: Nws muaj peev xwm tshawb fawb zoo hauv cov tsos mob tsis zoo ntawm kev ntxhov siab, kev nyuaj siab, thiab schizophrenia, nrog rau kev puas tsuaj rau lub cev.
Hauv cov ntsiab lus, nws yog tsuas yog siv rau hauv neuroscience, mitochondrial gene qhia thiab oxidative metabolism hauv kev tshawb fawb, nrog rau kev tshawb fawb txog kev puas hlwb.
Dab tsi yog qhov cuam tshuam ntawm SB 242084 dihydrochloride?
SB 242084 dihydrochloride hmoovmuaj cov teebmeem hauv qab no:
Pharmacological kev txiav txim: Nws yog ib qho kev xaiv, kev sib tw, thiab kev sib raug zoo siab 5-HT2C receptor antagonist uas tuaj yeem nkag mus rau hauv cov ntshav-hlwb teeb meem. Nws tuaj yeem ua kom cov haujlwm basal ntawm dopaminergic neurons nyob rau hauv ventral tegmental cheeb tsam (VTA) ntawm midbrain thiab tso tawm ntawm dopamine nyob rau hauv lub nucleus accumbens. Tsis tas li ntawd, nws tseem tuaj yeem ua rau mitochondrial noob qhia thiab oxidative metabolism los ntawm 5-HT2A receptors.
Kev tshawb fawb muaj peev xwm: Nws muaj peev xwm tshawb fawb zoo hauv cov tsos mob tsis zoo ntawm kev ntxhov siab, kev nyuaj siab, thiab tus mob schizophrenia, nrog rau kev puas tsuaj rau lub cev.
Thov nco ntsoov tias cov khoom no yog siv rau kev tshawb fawb txog kev tshawb fawb nkaus xwb thiab tsis tuaj yeem siv rau kev siv tshuaj, kev kuaj mob lossis kev kho mob, zaub mov, tshuaj pleev ib ce, thiab lwm yam. Thov hnav khaub ncaws hauv chav kuaj thiab cov hnab looj tes pov tseg thiab lub qhov ncauj qhov ntswg thaum ua haujlwm kom muaj kev nyab xeeb thiab noj qab haus huv.
Yuav ua li cas thiab qhov twg yuav SB 242084 dihydrochloride lag luam wholesale?
Peb cov khoom raug kuaj sim thiab tau lees paub los ntawm cov neeg siv khoom.
Koj tuaj yeem tso siab rau peb qhov kev txiav txim vim tias peb muaj cov ntaub ntawv zoo ntawm kev muag tshuaj raws cai.
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:sales2@faithfulbio.comTam sim no.
Muaj ntau txoj kev xa khoom rau koj xaiv
|
Tsheb thauj mus los |
Shipping txoj kev |
Cargo hnyav xav tau |
Qhov zoo |
|
3-7 hnub |
DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, |
Haum rau qis dua 50kg. |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, |
|
7-15 hnub |
Los ntawm Cua |
Haum rau ntau tshaj 50kg. |
|
|
15-60 hnub |
Los ntawm Hiav Txwv |
Haum rau ntau tshaj 500kg. |
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:sales2@faithfulbio.comTam sim no.
FAQ:
Q1:Koj muab kev xaiv ntim dab tsi?
A1:Peb muab ntau yam kev daws teeb meem, suav nrog: Hlau nruas, Yas nruas, IBC tso tsheb hlau luam, Flexitanks, ISO TANKS, Hnab (Lwm cov kev xaiv ntim tuaj yeem tham raws li cov neeg siv khoom xav tau).
Q2: Cov nqe lus them nqi dab tsi koj txais?
A2:Peb tsuas yog txais TT (Lub txhab nyiaj hloov pauv). Lwm txoj kev them nyiaj tuaj yeem sib tham.
Q3:Kuv puas tuaj yeem thov tus qauv?
A3:Cov qauv pub dawb muaj, tab sis tus nqi thauj khoom yuav tsum them los ntawm tus neeg yuav khoom. Rau siab - cov khoom muaj nqis, tus nqi piv txwv yuav raug siv.
Tsis lees paub: Cov ntaub ntawv muab rau hauv lub vev xaib no yog rau kev siv nkaus xwb thiab tsis lav qhov raug, siv tau, sijhawm sijhawm, lossis ua tiav ntawm cov ntaub ntawv. Thov lim kom zoo. Yog tias koj ntseeg tias tsab xov xwm no ua txhaum, thov hu rau tus thawj tswj hwm. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm cov ntaub ntawv thiab cov kev pabcuam hauv lub vev xaib no.
Nco tseg:Cov tshuaj no tsuas yog siv rau kev tshawb fawb hauv chav kuaj. Cov tub ceev xwm Asmeskas tsis tau ntsuas cov lus thov no. Ua ntej siv, thov nrog koj tus kws kho mob tham thiab kawm txog kev tshawb fawb muaj. Cov khoom no tsis yog npaj rau kev kuaj mob, kev kho mob, kev kho, lossis kev tiv thaiv kab mob.
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