Khoom Taw Qhia
SLU-PP-332 (lus pp) yog pan-estrogen receptor-related receptor (ERR) agonist nrog siab affinity rau ERR , ERR , thiab ERR nrog EC50 tus nqi ntawm 98, 230, thiab 430 nM, feem.
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| slu-pp Daim duab | swb-pp MF |
Khoom siv
SLU-PP-332 (SLU-PP) txhim kho mitochondrial muaj nuj nqi thiab cellular respiration, tsub kom hom IIa oxidative skeletal nqaij fibers, thiab txhim khu kev tawm dag zog siab nyob rau hauv skeletal nqaij cell kab. SLU-PP-332 muaj peev xwm siv tau rau hauv kev tshawb fawb ntawm cov kab mob metabolic thiab txhim kho cov leeg nqaij, thiab tuaj yeem siv los txhim kho cov kab mob metabolic thiab kev laus.
SLU-PP-332 yog lub lauj kaub uas tsis muaj tshuaj lom ERR / / (estrogen receptor-related receptors / / ) agonist nrog cov haujlwm tseem ceeb ERR (EC50=98, 230 & 430 nM tiv thaiv ERR , ERR & ER ) thiab ua raws li kev tawm dag zog mimetic. SLU-PP-332 qhia txog kev xaiv ntawm ER , ER thiab ntau lwm yam cuam tshuam nrog cov receptors nuclear. Nws induces Ddit4 qhia thiab txhim kho mitochondrial respiration nyob rau hauv C2C12 myocytes (10 µM) thiab siv endurance nyob rau hauv nas (50 mg / kg bid, ip) nyob rau hauv ib tug ERR -dependent yam.
SLU-PP-332 yog lub zog thiab xaiv cov tshuaj estrogen ntsig txog receptor (ERR) agonist (EC50 qhov tseem ceeb yog 98 nM, 230 nM thiab 430 nM rau ERR , ERR thiab ERR feem). Hauv cov qauv nas ntawm cov kab mob metabolic SLU-PP-332 nce kev siv hluav taws xob thiab fatty acid oxidation, txo cov rog rog, thiab txhim kho insulin rhiab heev. Kuj nce mitochondrial ua pa hauv vitro.
Khoom Specification
| Specification | Kev xav tau | Cov qhabnias xeem |
| Qhov tshwm sim | Dawb hmoov | Dawb hmoov |
| Assay | Ntau dua lossis sib npaug rau 99.0% | 99.13% |
| Poob Thaum Qhuav | Tsawg dua lossis sib npaug rau 1.0% | 0.29% |
| Residue ntawm Ignition | Tsawg dua lossis sib npaug rau 0.2% | 0.08% |
| Hnyav Hlau | Tsawg dua lossis sib npaug li 20ppm | <10ppm |
| Tag nrho cov phaj suav | Tsawg dua lossis sib npaug li 100cfu / G | Ua raws |
| Poov & Pwm | Tsawg dua lossis sib npaug li 100cfu / G | Ua raws |
| E. Coli | Tsis zoo | Ua raws |
| Xaus: Ua raws li kev lag luam specification. | ||
Yuav Ua Li Cas Kom Tau Txais Cov Qauvlus pp?
Txais tos kom xa ib qho kev nug rausunny@faithfulbio.comtxhua lub sijhawm rau tus qauv dawb yog tias koj xav tau APIlus pp.
Qhov zoo tshaj plaws slu-pP Chaw tsim tshuaj paus thiab tsum
Faithfulbio muaj kev paub dhau los hauv kev xa tawm cov ntaub ntawv raw thiab tau tsim kev sib raug zoo thiab kev koom tes ntev nrog peb cov neeg siv khoom. Peb ib txwm muab cov khoom zoo thiab kev pabcuam ua ntej. Yog tias koj muaj cov khoom siv raw khoom xav tau, thov hu rau peb. Peb tuaj yeem lees paub qhov kev txiav txim nrog koj raws li koj qhov yuav khoom ntau. Peb kuj txhawb peb txoj kev koom tes thawj zaug pib los ntawm cov qauv. Tsis tas li ntawd, peb txoj kev thauj mus los sai thiab nyab xeeb kuj ua rau koj tshem tawm cov teeb meem ntawm kev lis kev cai.
Peb muaj kev ntseeg siab ntawm peb cov khoom zoo, tab sis yog tias muaj teeb meem tom qab muag, peb yuav teb sai li sai tau thiab daws lawv nrog koj txoj hauv kev zoo tshaj plaws.
Vim Li Cas Xaiv Faithfulbiolus-pP?
Faithfulbio tshwj xeeb hauvlus pprau ntau xyoo, peb muab cov khoom ntawm tus nqi sib tw, thiab peb cov khoom yog qhov zoo tshaj plaws, vim tias peb nruj heev hauv cov khoom tsim thiab kev sim, thiab muaj kev ua tiav thiab paub tab. Tsis tas li ntawd, peb cov neeg ua haujlwm Cov lus hais rau cov khoom muaj kev sib tw heev.
Muaj ntau txoj kev xa khoom rau koj xaiv
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Tsheb thauj mus los |
Shipping txoj kev |
Cargo hnyav xav tau |
Qhov zoo |
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3-7 hnub |
DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, |
Haum rau qis dua 50kg. |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, |
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7-15 hnub |
Los ntawm Cua |
Haum rau ntau tshaj 50kg. |
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15-60 hnub |
Los ntawm Hiav Txwv |
Haum rau ntau tshaj 500kg. |
ua siab zoo ceeb toom:Sivlus pprau kev tshawb fawb nkaus xwb. Txhua lub tebchaw muaj kev pheej hmoo. Thov nrog koj tus kws kho mob tham thiab kawm txog cov kev tshawb fawb muaj ua ntej siv. Tsis tas li ntawd, cov lus piav qhia saum toj no ntawm qhov sib xyaw yog los ntawm cov ntaub ntawv online. Yog tias muaj kev ua txhaum cai, thov hu rau peb kom tshem tawm.
Qhov twg Yuav slu-pp?
Cia li xa email rausunny@faithfulbio.com, lossis xa koj qhov yuav tsum tau ua hauv daim ntawv hauv qab, peb muaj kev pabcuam txhua lub sijhawm!
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