Sulfamethoxazole yog dab tsi?
Sulfamethoxazole yog cov tshuaj tua kab mob dav dav. Nws muaj inhibitory nyhuv ntawm feem ntau gram-zoo thiab gram-negative kab mob.
Sulfamethoxazole hmoovyog ib tug dawb crystalline hmoov, tsw tsw thiab iab me ntsis. Melting point yog 168 degree. Yuav luag insoluble hauv dej, tab sis soluble hauv dilute hydrochloric acid, sodium hydroxide tov los yog ammonia daws.
Sulfamethoxazole yog ib qho nruab nrab sulfanilamide nrog broad-spectrum antibacterial nyhuv. Sulfonamides yog broad-spectrum bacteriostats, uas zoo ib yam li p-aminobenzoic acid (PABA) hauv cov qauv, thiab tuaj yeem sib tw nrog PABA los ua cov dihydrofolate synthase hauv cov kab mob, yog li tiv thaiv PABA los ntawm kev siv raw khoom los tsim cov folic acid uas xav tau los ntawm cov kab mob. , txo tus nqi ntawm tetrahydrofolate nrog metabolic kev ua ub no, thaum lub sij hawm tom kawg yog ib qho tseem ceeb ntawm cov kab mob mus rau synthesize purine, thymidine thiab deoxyribonucleic acid (DNA), yog li inhibiting kev loj hlob thiab kev loj hlob ntawm cov kab mob.
| Khoom npe | Sulfamethoxazole |
| CAS | 723-46-6 |
| Cov mis mos molecular | C10H11N3O3S |
| Molecular hnyav | 253.28 |
| EINECS Number | 211-963-3 |
| Kev cia khoom | Khaws nyob rau hauv qhov chaw tsaus, inert cua, chav tsev kub |
| Melting point | 166 degree |
| Solubility | Yuav luag insoluble hauv dej, soluble hauv acetone thiab me ntsis soluble hauv ethanol (96%). Soluble nyob rau hauv dilute sodium hydroxide tov thiab dilute acid. |
| Qhov tshwm sim | Dawb rau lub teeb daj hmoov |
| Boiling point | 482 degree |
| Qhov ntom | 1.3915 (zeeg) |
Yuav ua li cas yog lub mechanism ntawm kev txiav txim ntawm sulfamethoxazole?
Peb paub tias cov kab mob xav tau tetrahydrofolate, folic acid derivative, raws li nws cov khoom pabcuam los ua ke thymidine, purine thiab thaum kawg DNA. Feem ntau cov kab mob tsis tuaj yeem tso cai rau folic acid nkag mus, tab sis yuav tsum tau ua ke nrog p-aminobenzoic acid (PABA). Sulfonamides zoo ib yam li PABA hauv cov qauv, yog li lawv tuaj yeem cuam tshuam cov synthesis ntawm dihy-dropteroicacid, ncaj qha precursor ntawm dihydrofolate, los ntawm PABA thiab pteridine. Mammalian hlwb tsis inhibited vim tias lawv xav tau folic acid ua ntej thiab tsis tuaj yeem tsim nws.Sulfamethoxazole hmoovFeem ntau yog cov kab mob bacteriostatic, tab sis thaum cov kab mob loj hlob hauv cov substrate uas muaj purine thiab amino acid thiab cov concentration ntawm thyminelessdeath tsawg, raug rau sulfanilamide tuaj yeem tsim cov kab mob bactericidal, uas yog, "thymine deficiency death". Cov kab mob bactericidal no tau raug pov thawj hauv tib neeg cov ntshav thiab zis (Tom qab ntawd thiab Angehrn, 1973A thiab b; Saib kuj Pratt thiab Fekety, 1986). Qhov inhibition ntawm kev loj hlob ntawm cov kab mob uas tshwm sim los ntawm sulfonamides tuaj yeem thim rov qab yog tias qee yam tshuaj (xws li thymidine, purine, methionine thiab serine) tau ntxiv rau kev loj hlob matrix hauv vitro. Qhov xwm txheej no yuav muaj qhov tseem ceeb hauv kev kho mob, vim tias cov kua paug uas tsim los ntawm kev puas tsuaj ntawm tes yuav muaj ntau yam ntawm cov tshuaj no, yog li cov tshuaj yeeb tshuaj yuav raug cuam tshuam vim muaj cov tshuaj no nyob rau hauv cov kab mob purulent. Tsis tas li ntawd, thaum kuaj cov tshuaj rhiab heev hauv vitro, yuav tsum tsis muaj PABA nyob rau hauv kab lis kev cai nruab nrab, txawm tias ib qho me me tuaj yeem cuam tshuam cov txiaj ntsig kev xeem.
Khoom Specification
| Yam khoom | Specification | Cov txiaj ntsig |
| Qhov tshwm sim | Hmoov | Ua raws |
| Xim | Dawb hmoov hmoov | Ua raws |
| Particle Loj | 100% dhau 80 mesh | Ua raws |
| Oder | Yam ntxwv | Ua raws |
| Saj | Yam ntxwv | Ua raws |
| Poob rau ziab | Tsawg dua lossis sib npaug rau 5.0% | 2.20% |
| Residue ntawm Ignition | Tsawg dua lossis sib npaug rau 0.1% | 0.05% |
| Heave Hlau | Tsawg dua lossis sib npaug li 10ppm | Ua raws |
| Na | Tsawg dua lossis sib npaug rau 0.1% | <0.1% |
| Pb | Tsawg dua lossis sib npaug li 3 ppm | Ua raws |
| Total Phaj | <1000CFU/g | Ua raws |
| Poov & Pwm | <100 CFU /g | Ua raws |
| E. Coli | Tsis zoo | Ua raws |
| Salmonella | Tsis zoo | Ua raws |
| Xaus: Ua raws li USP Standard | ||
Dab tsi yog kev siv ntawm sulfamethoxazole?
1. Sulfamethoxazole hmoovyog ib qho sulfonamide, uas yog siv los kho cov kab mob urinary mob thiab mob ntev, nrog rau kev tiv thaiv kab mob meningitis thiab mob otitis media tshwm sim los ntawm kab mob khaub thuas Bacillus.
2. Nws yog ib qho tshuaj tiv thaiv kab mob, uas yog siv los tiv thaiv kab mob urinary, kab mob ua pa, kab mob hauv plab, kab mob Salmonella, mob otitis media hauv cov menyuam yaus thiab mob meningitis.
3. Raws li ib tug antibacterial neeg sawv cev, nws yog tshwj xeeb tshaj yog zoo rau staphylococcus thiab Escherichia coli. Nws yog tsuas yog siv los kho nqaij qaib cholera.
4. Sulfamethoxazole tuaj yeem tiv thaiv kev loj hlob ntawm cov kab mob, tshwj xeeb tshaj yog rau cov kab mob staphylococcus thiab Escherichia coli, thiab muaj txiaj ntsig zoo rau kev kho cov kab mob urinary thiab nqaij qaib littering.
5. Sulfamethoxazole yog sulfonamide tshuaj tua kab mob, uas inhibits dihydropterate synthase, yog li thaiv cov synthesis ntawm dihydrofolate. Hom kev ua: inhibiting cov synthesis ntawm folic acid hauv prokaryotes.
HTML5 atlas of sulfamethoxazole
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Kev siv ntawm sulfamethoxazole:
1. Kev sib xyaw ua ke ntawmSulfamethoxazole hmoovthiab paracetamol tuaj yeem ua kom ntev lossis ntxiv dag zog rau cov kab mob tua kab mob ntawm sulfamethoxazole, nce ntshav concentration ntawm sulfamethoxazole thiab txhim kho cov nyhuv curative.
2. Kev kho mob ntawm qaib rhinitis: sulfamethoxazole 20 g + sulfadimethoxine sodium 20 g + cyclopropyl lactate 15 g + tmp lactate 8 g + paracetamol 15 g (qhov ntau npaum li cas yog 300-400 kg dej), thiab qhov ntau npaum li cas yuav tsum tau nce los yog txo qis raws li qhov mob hnyav.
3. Kho cov kab mob thiab kab mob Streptococcus pneumoniae. 20 g ntawm sulfamethoxazole +20 g ntawm sulfamethoxazole sodium +8 g ntawm trimethoprim (300 kg dej).
4. Kev kho cov kab mob enteritis: SMZ-20 g + Kanamycin 15 g + Tinidazole 15 g + Lactic acid TMP 7 g (qhov ntau npaum li cas yog 250-300 kg dej), cov SMZ + Kanamycin yog ib qho ntawm thawj xaiv tshuaj rau qaib plab hnyuv kab mob, ntxiv rau nws pom tseeb synergistic nyhuv. Nyob rau tib lub sijhawm, qhov sib xyaw Tinidazole tuaj yeem nthuav dav kom tsis muaj menyuam ntau ntawm cov kab mob tua kab mob. Qhov tseem ceeb tshaj, qhov sib ntxiv ntawm Lactic acid TMP,
5. Cov kab mob nqaij qaib Candida albicans: Miconazole + sulfamethoxazole, ua ke nrog ob cov tshuaj, tuaj yeem txhim kho kev tiv thaiv kab mob candida albicans hauv vitro.
6. Levamisole ua ke nrog cov tshuaj sulfamethoxazole feem ntau yog siv los kho cov nqaij qaib toxoplasmosis, uas tuaj yeem rhuav tshem cov kab mob, txo cov tshuaj tiv thaiv antigen thiab txhim kho cov tsos mob.
7. Tylosin + SMZ + TMP lactate tuaj yeem siv rau kev tiv thaiv thiab kho cov kab mob swine dysentery, kab mob ntsws, enteritis, poultry cholera, thiab cov kab mob nqaij qaib.
Puas yog Sulfamethoxazole yog tshuaj tua kab mob?
Sulfamethoxazole belongs rau sulfanilamide tshuaj tua kab mob, thiab sulfamethoxazole tuaj yeem siv los kho cov kab mob urinary yooj yim los ntawm cov kab mob rhiab heev. Tsis tas li ntawd, thaum mob cervicitis lossis urethritis tshwm sim los ntawm tus kab mob chlamydia trachomatis tshwm sim, Sulfamethoxazole kuj tseem siv tau raws li kev qhia ntawm tus kws kho mob.
Sulfamethoxazole ua ke nrog trimethoprim kuj tuaj yeem siv los kho otitis media los ntawm Streptococcus pneumoniae thiab Haemophilus influenzae. Tsis tas li ntawd, cov neeg mob chancre tshwm sim los ntawm Haemophilus duklei kuj tuaj yeem siv sulfamethoxazole raws li tau hais tseg.
Dab tsi yog cov kev ceev faj rau kev siv Sulfamethoxazole hmoov?
1. Hla kev ua xua. Cov neeg mob uas tsis haum rau ib qho sulfonamide kuj yuav ua xua rau lwm cov sulfonamides.
2. Daim siab puas. Jaundice, daim siab ua haujlwm poob qis thiab mob siab rau lub siab necrosis tuaj yeem tshwm sim hauv cov xwm txheej hnyav, yog li cov neeg mob siab ua haujlwm yuav tsum tsis txhob siv.
3. Lub raum puas. Cov zis crystalline, hematuria thiab cov zis tubular tuaj yeem tshwm sim, yog li koj yuav tsum haus dej ntau dua thiab tswj cov zis siab thaum siv Sulfamethoxazole los tiv thaiv qhov tshwm sim tsis zoo no.
5. Cov neeg mob uas tsis haum rau furosemide, irony, thiazide diuretics, sulfonylureas thiab carbonic anhydrase inhibitors kuj yuav ua xua rau sulfonamides.
6. Cov tshuaj ntshav siab ntawm cov neeg mob hnyav yuav tsum tau txiav txim siab, uas yog qhov zoo rau cov neeg mob feem ntau kis kab mob nrog dawb sulfanilamide concentration ntawm 50 ~ 150ug / ml (120 ~ 150 ug / ml rau cov neeg mob hnyav).
Yuav ua li cas thiab qhov twg yuav Sulfamethoxazole Powder wholesale?
Koj tuaj yeem tso siab rau peb qhov kev txiav txim vim tias peb muaj cov ntaub ntawv zoo ntawm kev muag tshuaj raws cai.
Peb ua qhov kev kuaj xyuas ywj pheej ntawm txhua yam khoom thiab tom qab ntawd muag rau peb cov neeg siv khoom hwm.
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:allen@faithfulbio.comTam sim no.
Muaj ntau txoj kev xa khoom rau koj xaiv
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Tsheb thauj mus los |
Shipping txoj kev |
Cargo hnyav xav tau |
Qhov zoo |
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3-7 hnub |
DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, |
Haum rau qis dua 50kg. |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, |
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7-15 hnub |
Los ntawm Cua |
Haum rau ntau tshaj 50kg. |
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15-60 hnub |
Los ntawm Hiav Txwv |
Haum rau ntau tshaj 500kg. |
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:allen@faithfulbio.comTam sim no.
Tsis lees paub: Cov ntawv luam tawm ntawm lub xaib no yog siv los txhawb kev sib pauv kev kawm thiab kev kawm, thiab tsis txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm nws cov ntsiab lus. Thov lim kom zoo. Yog tias koj ntseeg tias tsab xov xwm no ua txhaum, thov hu rau tus thawj tswj hwm. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv cov ntaub ntawv thiab cov kev pabcuam hauv lub vev xaib no.
Nco tseg: Cov tshuaj no yuav tsum tau siv rau kev tshawb fawb nkaus xwb. Cov lus thov no tsis tau raug soj ntsuam los ntawm Food and Drug Administration. Thov nrog koj tus kws kho mob tham thiab kawm txog cov kev tshawb fawb muaj ua ntej siv lawv. Cov khoom no tsis yog tsim los kuaj xyuas, kho, kho, lossis tiv thaiv txhua yam kab mob.
Cim npe nrov: sulfamethoxazole hmoov cas 723-46-6, Suav teb, lwm tus neeg, manufacturers, hoobkas, customized, lag luam wholesale, yuav, nqe, tej, ntshiab, tsim, luv nqi, kev muag, Tshuag, dawb qauv, raw hmoov, raw khoom, ua nyob rau hauv Tuam Tshoj