Tazobactam acid yog dab tsi?
Tazobactam acidyog ib qho extruded phthalamidase inhibitor synthesized los ntawm 6_ aminopenicillanic acid.
Tazobactam acid hmoov yog cov xim tsis muaj xim crystalline hmoov uas tsis muaj solubility hauv dej, tab sis zoo solubility hauv cov organic solvents. Tazobactam acid yog ib qho chaw ruaj khov, uas tsis yooj yim decomposed los ntawm lub teeb, tshav kub thiab oxidant.
Tazobactam yog ob qho tib si -lactam tshuaj tua kab mob thiab -lactamase inhibitor, tab sis nws cov tshuaj tua kab mob tsis muaj zog heev. Tazobactam yog ib qho derivative ntawm sulbactam, thiab nws cov tshuaj tua kab mob muaj zog dua li clavulanic acid thiab sulbactam.
Vim hais tias cov nyhuv antibacterial ntawm tazobactam nws tus kheej yog me me, tazobactam tsis tshua siv ib leeg ua tshuaj tua kab mob, thiab feem ntau nws yog siv ua ke.
| Khoom npe | Tazobactam acid |
| CAS | 89786-04-9 |
| Cov mis mos molecular | C10H12N4O5S |
| Molecular hnyav | 300.29 |
| EINECS Number | 618-303-7 |
| Kev cia khoom | Muab kaw rau hauv qhuav, Khaws rau hauv lub tub yees, hauv qab -20 degree |
| Melting point | 115-145 degree |
| Solubility | DMSO (kub me ntsis), methanol (kub me ntsis, kho ultrasonically) |
| Qhov tshwm sim | Dawb mus rau dawb hmoov |
| Boiling point | 77 degree |
| Qhov ntom | 1.92 ± 0.1 g / cm3 (Tshaj tawm) |
Dab tsi yog pharmacological kev txiav txim ntawm Tazobactam acid?
Tazobactam acid, ib tug derivative ntawm sulbactam, yog ib tug irreversible kev sib tw -lactamase inhibitor, uas muaj zog inhibitory teebmeem ntawm penicillinase tsim los ntawm Staphylococcus aureus, plasmid-mediated-lactamase tsim los ntawm Gram-negative bacilli thiab chromosome-mediated-lactamase uas tsim los ntawm Proteoides thiab Bacillus. . Qhov inhibition ntawm enzyme yog zoo dua li ntawm clavulanic acid thiab sulbactam, thiab nws kuj inhibited ib co chromosome-mediated hom ⅰ enzymes. Nws muaj me ntsis cuam tshuam rau Pseudomonas aeruginosa thiab Serratia. Tsuas yog tsis muaj zog tiv thaiv kab mob.
Khoom Specification
| Yam khoom | Specification | Cov txiaj ntsig |
| Qhov tshwm sim | Dawb los yog dawb crystalline hmoov | Off-dawb hmoov |
| Kev txheeb xyuas | Lub sijhawm khaws cia ntawm lub ncov loj sib raug rau qhov kev npaj ua ntej | Ua raws |
| Kev sib hloov tshwj xeeb | +127 degree ~ +139 degree | 130ºC |
| dej | Tsawg dua lossis sib npaug rau 1.0% | 0.21% |
| Acidity | 2.0-2.5 | 2.2 |
| Cov khoom muaj feem xyuam | ||
| Tus kheej impurity | Tsawg dua lossis sib npaug rau 0.1% | 0.09% |
| Tag nrho impurities | Tsawg dua lossis sib npaug rau 1.0% | 0.10% |
| B impurity | B Tsawg dua lossis sib npaug rau 1.0% | 0.06% |
| Residue ntawm ignition | Tsawg dua lossis sib npaug rau 0.1% | 0.03% |
| Cov hlau hnyav | Tsawg dua lossis sib npaug rau 0.002% | 0.0001% |
| Assay | 98.0% -102.0% | 99.80% |
| Xaus | Ua raws li USP Standard. | |
Tazobactam acid tuaj yeem siv rau qhov twg?
1. Kev thov ua liaj ua teb:Tazobactam acidfeem ntau yog siv los tswj cov kab mob ntawm cov qoob loo. Nws tuaj yeem tiv thaiv kab mob gamasid mite, kab mob scab, hauv paus rot ntawm zaub thiab lwm yam kab mob.
2. Muaj daim ntawv thov: Tazobactam kuj tseem siv tau rau cov kab mob mildew-pov thawj thiab tshuaj tua kab mob ntawm cov ntoo, pulp thiab textiles.
HTML5 atlas ntawm Tazobactam acid
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Lub luag haujlwm ntawm Tazobactam acid yog dab tsi?
1. Tazobactam Acidyog ib tug -lactamase inhibitor ntawm penicillanine sulfones, uas yog zoo rau kuv ~ VI hom 3- lactamases, tshwj xeeb tshaj yog rau kuv hom. Nws muaj toxicity tsawg, zoo stability thiab muaj zog enzyme inhibition kev ua.
2. -lactamase inhibitor, thib peb tiam ntawm muaj zog antibacterial synergist, ua ke nrog piperacillin los yog cefoperazone tuaj yeem txhim kho qhov ua tau zoo thiab ua kom lub sijhawm ua haujlwm ntawm ob qho tib si. Thaum tazobactam sodium yog siv ua ke nrog piperacillin sodium, nws muaj cov nyhuv synergistic, wider antibacterial spectrum thiab indications tshaj lwm cov tshuaj tua kab mob uas tau siv, thiab qhia tau hais tias zoo zoo nyob rau hauv kov yeej tshuaj tiv thaiv.
Dab tsi yog qhov txawv ntawm Tazobactam acid thiab sulbactam ??
Sulbactam yog ib qho hluavtaws sulfone-lactamase inhibitor. Zoo ib yam li clavulanic acid, nws yog ib qho tseem ceeb ntawm chav kawm A -lactamase inhibitor, thiab inhibitory mechanism ntawm clavulanic acid feem ntau yog siv rau sulbactam. Cov txheej txheem ntawm sulbactam inhibition ntawm -lactamase tau lees paub tias zoo ib yam li clavulanic acid. Yog li ntawd, ntau cov noob hloov pauv uas txo cov kev ua ntawm clavulanic acid kuj txo qhov inhibitory kev ua ntawm sulbactam. Tazobactam Acid yog ib qho muaj zog -lactamase inhibitor tau txais tom qab kev hloov kho ntawm sulbactam. Nws tseem yog ib yam khoom uas muaj cov nyhuv zoo heev thiab daim ntawv thov kev cia siab ntawm -lactamase inhibitors ntawm kev ua lag luam.
Tazobactam Acidmuaj qhov zoo ntawm cov tshuaj toxicity tsawg, muaj zog enzyme inhibition kev ua si thiab zoo stability. Tam sim no nws yog qhov pheej hmoo tshaj plaws -lactamase inhibitor. Nws tuaj yeem siv rau cov kab mob nruab nrab thiab hnyav tshwm sim los ntawm -lactamase-ua cov kab mob resistant rau -lactam nplhaib tshuaj tua kab mob, tsis yooj yim thiab nyuaj ntawm daim tawv nqaij thiab cov nqaij mos kab mob, thiab lwm yam. Tazobactam Acid tsis zoo soluble hauv dej. Nws tuaj yeem npaj rau hauv sterile lyophilized hmoov ntawm Tazobactam sodium los ntawm hnyav crystallization lossis lyophilization. Tazobactam sodium yog daim ntawv tshuaj ntawm Tazobactam Acid. Kev npaj ntawm nws cov hydrate kov yeej qhov tsis muaj zog ntawm Tazobactam sodium ua hygroscopic heev. Ib yam li ntawd, Tazobactam hemihydrate yog ib daim ntawv siv lead ua ruaj khov ntawm Tazobactam (acid), uas khaws cov enzyme inhibitory kev ua ntawm Tazobactam sodium, tsis yog hygroscopic, muaj kev ruaj ntseg zoo dua li Tazobactam sodium, thiab muaj toxicity tsawg heev.
Tazobactam acid npaj li cas?
6-Aminopenicillanic acid (6-APA) tau siv los ua cov khoom siv raw. Tom qab bromination, esterification, oxidation thiab debromination rau sulfoxide, nws tau reacted nrog triazole, oxidized dua, thiab deprotected kom tau Tazobactam. Cov txiaj ntsig: Cov sulfoxide tau oxidized nrog 30% hydrogen peroxide thiab reacted nrog 2-trimethylsilyl-1,2,3-triazole los tsim -methyl-2 -(1,2,{{ 11}}triazol-1-yl)methylpenicillanic acid-3 -carboxylic acid diphenylmethyl ester. Txoj kev no ua rau luv luv cov tshuaj tiv thaiv kab mob, yooj yim rau kev khiav lag luam, thiab muaj tag nrho cov txiaj ntsig ntawm 24%.
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Puas yog Tazobactam acid yog tshuaj tua kab mob?
Tazobactam Acidbelongs rau cyclic peptide tshuaj tua kab mob.
Tazobactam yog tshuaj tua kab mob polypeptide, uas yog ib hom tshuaj tua kab mob cyclic peptide.
Tazobactam yog cov tshuaj tua kab mob dav dav, uas tuaj yeem tua tau Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella pneumoniae thiab lwm yam kab mob uas tiv thaiv kab mob, tab sis nws cov tshuaj tua kab mob tsis zoo. Nws muaj cov nyhuv tua tau zoo ntawm qee cov kab mob uas tiv taus tshuaj, xws li Klebsiella pneumoniae resistant rau carbon penicillin thiab Acinetobacter baumannii resistant rau carbon penicillin. Nws cov txheej txheem yog los rhuav tshem cov cell membrane ntawm cov kab mob thiab ua rau cell tuag. Nyob rau tib lub sijhawm, qhov tsis zoo tshwm sim ntawm tazobactam tsawg dua, thiab cov tshuaj tiv thaiv tsis yooj yim tshwm sim.
Nyob rau hauv ib lo lus, tazobactam yog ib tug dav-spectrum antibacterial neeg sawv cev, uas muaj ib tug zoo kho nyhuv ntawm gram-negative kab mob.
Dab tsi yog qhov ceev faj ntawm Tazobactam acid?
1. Tazobactam acid yuav tsum tau ua ke nrog -lactam tshuaj tua kab mob, thiab cov nyhuv antibacterial tsis muaj zog thaum siv ib leeg.
2. Penicillin daim tawv nqaij yuav tsum tau ua ua ntej siv, thiab cov neeg uas zoo yog txwv tsis pub.
3. Cov tshuaj tiv thaiv kab mob sib kis: cov neeg uas tsis haum rau ib qho tshuaj tua kab mob penicillin kuj tseem yuav ua xua rau lwm yam tshuaj tua kab mob penicillin.
4. Lub siab thiab lub raum ua haujlwm thiab hematopoiesis yuav tsum tau kuaj tsis tu ncua thaum siv tshuaj ntau.
6. Xa mus rau qhov sib xyaw ua ke ntawm cov khoom no thiab -lactam tshuaj tua kab mob.
Yuav ua li cas thiab qhov twg yuav Tazobactam Powder wholesale?
Koj tuaj yeem tso siab rau peb qhov kev txiav txim vim tias peb muaj cov ntaub ntawv zoo ntawm kev muag tshuaj qhia kev cai lij choj.
Peb ua qhov kev kuaj xyuas ywj pheej ntawm txhua yam khoom thiab tom qab ntawd muag rau peb cov neeg siv khoom hwm.
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:allen@faithfulbio.comTam sim no.
Muaj ntau txoj kev xa khoom rau koj xaiv
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Tsheb thauj mus los |
Shipping txoj kev |
Cargo hnyav xav tau |
Qhov zoo |
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3-7 hnub |
DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, |
Haum rau qis dua 50kg. |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, |
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7-15 hnub |
Los ntawm Cua |
Haum rau ntau tshaj 50kg. |
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15-60 hnub |
Los ntawm Hiav Txwv |
Haum rau ntau tshaj 500kg. |
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:allen@faithfulbio.comTam sim no.
Tsis lees paub: Cov ntawv luam tawm ntawm lub xaib no yog siv los txhawb kev sib pauv kev kawm thiab kev kawm, thiab tsis txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm nws cov ntsiab lus. Thov lim kom zoo. Yog tias koj ntseeg tias tsab xov xwm no ua txhaum, thov hu rau tus thawj tswj hwm. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv cov ntaub ntawv thiab cov kev pabcuam hauv lub vev xaib no.
Nco tseg: Cov tshuaj no yuav tsum tau siv rau kev tshawb fawb nkaus xwb. Cov lus thov no tsis tau raug soj ntsuam los ntawm Food and Drug Administration. Thov nrog koj tus kws kho mob tham thiab kawm txog cov kev tshawb fawb muaj ua ntej siv lawv. Cov khoom no tsis yog tsim los kuaj xyuas, kho, kho, lossis tiv thaiv txhua yam kab mob.
Cim npe nrov: tazobactam acid cas 89786-04-9, Suav teb, lwm tus neeg, manufacturers, hoobkas, customized, lag luam wholesale, yuav, nqe, tej, ntshiab, tsim, luv nqi, muag, Tshuag, dawb qauv, raw hmoov, raw khoom, ua nyob rau hauv Tuam Tshoj