VimIpriflavone ntsiav tshuajmuaj cov nyhuv inhibiting pob txha absorption, cov tshuaj no muaj ib tug kuj zoo kho nyhuv thaum siv los kho osteoporosis. Kev xyaum kho mob qhia tau hais tias cov tshuaj no yeej pab tau ntau tus neeg mob kom txo tau cov tsos mob hauv lub sijhawm thiab ua tau zoo, thiab pab cov neeg mob kom txo tau qhov mob los ntawm tus kab mob. Yog li nws yog qhov tsim nyog rau cov neeg mob kom kawm paub ntau ntxiv txog kev paub dav dav ntawm cov ntsiav tshuaj Ipriflavone, yog li cia peb nkag siab txog cov tshuaj pharmacological ntawm Ipriflavone ntsiav tshuaj?
Ipriflavone yog ib hom isoflavone derivative, teej tug mus rau phytoestrogens. Nws tuaj yeem ua ncaj qha rau pob txha, inhibit pob txha nqus, thiab ua los ntawm kev txhim kho estrogen los txhawb cov thyroid kom tso calcitonin. Yog li, nws muaj qee qhov kev kho mob ntawm estrogen thiab calcitonin. Vim tias nws tsuas yog cov txheej txheem physiological metabolic hauv lub cev, nws tsis muaj kev phiv ntawm ob qho tib si.
Ntau cov ntaub ntawv tshawb fawb tau lees paub tias Ipriflavone muaj cov tshuaj hauv qab no:
(1) Txhawb kev loj hlob ntawm osteoblasts, txhawb kev tsim thiab mineralization ntawm cov pob txha collagen, thiab nce pob txha loj;
(2) Txo qhov kev loj hlob thiab kev sib txawv ntawm osteoclast precursor hlwb, inhibit qhov kev ua ntawm osteoclasts, thiab txo cov pob txha resorption;
(3) Nws nce qhov tso tawm ntawm calcitonin los ntawm kev ua haujlwm zoo li estrogen, thiab tsis ncaj qha ua rau cov pob txha nqus cov nyhuv. Cov no kuj tau dhau los ua lub hauv paus pharmacological rau kev kho mob osteoporosis.
Feem ntau, nrog rau cov hnub nyoog nce, cov pob txha pob txha pob txha ntom ntom (BMD) txo qis dua, qhov kev pheej hmoo ntawm pob txha tawg tuaj yeem nce ntxiv, thiab qhov tshwm sim ntawm pob txha pob txha tuaj yeem ncav cuag li 21 feem pua. Kev kho mob nrog ipriflavone tuaj yeem txo qhov tshwm sim ntawm pob txha pob txha los ntawm 50 feem pua. Yog li ntawd, ipriflavone muaj lub luag haujlwm tseem ceeb hauv kev tiv thaiv qhov tshwm sim ntawm cov pob txha tshiab hauv cov neeg mob osteoporosis.
Yuav ua li cas tiv thaiv thiab kho osteoporosis nrog ipriflavone?
Ipriflavone tuaj yeem tiv thaiv thiab kho osteoporosis los ntawm cov txheej txheem hauv qab no:
Ua ntej, cov tshuaj no tuaj yeem cuam tshuam ncaj qha rau pob txha nqus tom qab thov. Tom qab cov tshuaj tau noj rau hauv tib neeg lub cev, lawv tuaj yeem cuam tshuam tus naj npawb ntawm osteoclasts thiab inhibit lawv cov haujlwm, yog li txo qis tus cwj pwm osteoclast hauv cov pob txha.
Qhov thib ob, cov tshuaj no tuaj yeem txhawb kev tsim cov pob txha. Tom qab siv cov tshuaj no, lawv tuaj yeem koom tes nrog cov tshuaj estrogen los txhawb lub caj pas parathyroid, thiab tom qab ntawd nce qhov tso tawm ntawm cov tshuaj hormones parathyroid. Nyob rau lub sijhawm no, osteoblasts hauv cov pob txha tuaj yeem raug txhawb kom nce lawv tus cwj pwm osteogenic, thiab tom qab ntawd cov pob txha loj ntawm tus neeg mob yuav rov qab los.
Cov tshuaj no tsuas yog siv tau rau cov neeg mob postmenopausal thiab senile osteoporosis. Tom qab siv, nws tuaj yeem cuam tshuam qhov txo qis ntawm cov pob txha, ncua cov txheej txheem ntawm pob txha, tswj cov calcium zoo, thiab txhim kho qhov mob ntawm nraub qaum.
Cov txheej txheem saum toj no tsuas yog siv rau kev siv xwb. Thov siv cov tshuaj tshwj xeeb raws li kev qhia ntawm tus kws kho mob ua ke nrog koj tus kheej qhov xwm txheej.
Cov ntaub ntawv hauv kab lus no yog los ntawm Is Taws Nem thiab tsis siv los ua cov lus qhia txog kev kho mob lossis cov lus qhia peev. Yog tias tsab xov xwm no muaj kev cuam tshuam rau koj txoj cai thiab kev txaus siab lossis xav paub txog cov khoom no, thov hu rau peb raws sijhawm kom peb tuaj yeem muab kev pab ntxiv rau koj