S-acetyl L-glutathione is a glutathione variant. （Glutathione is a tripeptide compound condensed by glutamic acid, cysteine, and glycine through a peptide bond. It is the most important low molecular mercaptan in mammalian cells under antioxidant stress. It was discovered in 1921. Dr. al Mindel, a famous American Nutrition and health care expert, said that glutathione is an anti-aging amino acid with three times the efficiency. It is widely distributed in various organs of the human body. It mainly plays a role in maintaining the biological function of cells and protecting the integrity of the cell membranes. Clinically, it is used in the treatment and adjuvant treatment of a variety of diseases, including chemotherapy patients, radiotherapy patients, various hypoxemia, liver diseases, drug toxicity, and so on） S-acetyl L-glutathione attaches acetyl functional groups to glutathione, which makes the structure of glutathione more stable and more conducive to the absorption of the body. It is a high molecular biological product conducive to oral absorption.
Dab tsi yog qhov xwm txheej ntawmS-acetyl L-glutathionenyob rau hauv tib neeg lub cev?
Acetyl glutathione txhim kho nws txoj kev ncaj ncees nyob rau hauv cov hnyuv thiab siab concentration yog absorbed los ntawm peb cov ntshav. Glutathione yog ib qho antioxidant zoo heev thiab yog ib txwm tsim los ntawm lub cev (thiab yog tib lub cev hauv lub cev). Nws tau pom tias txhawb kev noj qab haus huv neuronal, lub siab ua haujlwm, thiab kev tiv thaiv kab mob. Tom qab muaj hnub nyoog 45 xyoos, lub cev pib tsim cov glutathione tsawg dua, thiab ntau tus neeg pib tswj lawv cov qib glutathione los ntawm kev ntxiv. Hmoov tsis zoo, feem ntau cov tshuaj glutathione muaj me ntsis bioavailability vim tias cov molecule tawg sai sai tom qab kev tswj qhov ncauj.S-acetyl-l-glutathioneyog ib daim ntawv hloov nrog acetyl functional pawg. Qhov no zoo heev txhim kho nws lub peev xwm kom nyob twj ywm hauv txoj hnyuv thiab tso cai rau ntau dua kom nqus tau rau hauv cov ntshav thiab ua lub luag haujlwm nyob ntawd.
Kev sib xyaw ua ke ntawm glutathione precursor thiab lwm cov as-ham zoo li cas?
Raws li tau pom los ntawm cov saum toj no,s-acetyl-l-glutathionethiab glutathione yeej ib txwm zoo ib yam, yog li peb yuav muaj lus nug txog cov nyhuv ntawm cov qauv zoo li no nrog rau lwm yam khoom.
NAC (N-acetylcysteine) yog ib txoj hauv kev zoo los ntxiv glutathione. Tom qab kev tswj hwm qhov ncauj ntawm NAC, NAC tau nqus hauv cov hnyuv thiab metabolized rau hauv cysteine hauv daim siab. Cysteine yog tus nqi - txwv cov substrate ntawm glutathione. Tshwj tsis yog tias daim siab ua haujlwm raug puas tsuaj, NAC supplementation tuaj yeem ua kom cov qib glutathione hauv lub cev.
Kev tawm dag zog ntau dhau yuav ua rau oxidative kev nyuaj siab rau lub cev thiab txo qis glutathione hauv lub cev. Hauv kev tshawb fawb ob - qhov muag tsis pom kev ntawm pawg tswj hwm tau tshaj tawm xyoo 2018, cov ntsiab lus tau muab faib ua peb pawg raws li qib glutathione hauv lub cev. Cov kev kawm hauv qib siab - theem, nruab nrab- theem thiab qis - qib glutathione pawg tau ntxiv nrog 600mg x 2 NAC txhua hnub rau 30 hnub sib law liag. Tom qab lub sijhawm sim, nws tau pom tias NAC tuaj yeem nce glutathione, tab sis nws tsuas tuaj yeem txhim kho cov ntsiab lus hauv qib qis - qib glutathione. Qhov xaus ntawm txoj kev tshawb no yog tias NAC tuaj yeem nce qib glutathione ntawm cov neeg tsis muaj glutathione thiab txo cov kev ntxhov siab oxidative.
Paracetamol tej zaum yuav yog cov tshuaj OTC siv tshaj plaws. Peb pib siv cov tshuaj paracetamol rau mob khaub thuas, mob taub hau, mob plab, mob hniav...Thiab qee cov neeg siv nws ntau xyoo. Tab sis txawm tias acetaminophen yog suav tias yog ib koob tshuaj zoo, nws tuaj yeem ua rau muaj kev ntxhov siab rau daim siab. Hauv ob- pab pawg tswj qhov muag tsis pom kev tshawb fawb hauv 2018, cov neeg noj qab haus huv tau siv 1g x 4 paracetamol txhua hnub rau 4 hnub sib law liag. Nws tau pom tias qib glutathione hauv cov ntsiab lus tau txo qis, tab sis NAC supplementation tuaj yeem tswj hwm qib glutathione ntawm cov kev kawm tsis hloov.
Kev qaug zog tom qab kev tawm dag zog yog cuam tshuam nrog kev txo qis ntawm glutathione los ntawm oxidative kev nyuaj siab tom qab kev tawm dag zog. Nyob rau hauv kev tshawb fawb soj ntsuam nyob rau hauv 2005, tom qab cov kev kawm coj lub dab teg zog ce, pab pawg neeg cuam tshuam tau ntxiv nrog NAC (150 mg / kg lub cev hnyav), thaum pawg tswj tsuas muaj saline ib txwm. Tom qab rov ua dua lub dab teg lub zog, qhov qaug zog ntawm pawg NAC cuam tshuam tau qeeb los ntawm 30 feem pua, oxidation ntawm glutathione kuj raug txo, thiab kev ua haujlwm ntawm lub dab teg lub zog kuaj tau zoo dua los ntawm 15 feem pua. Qhov xaus ntawm txoj kev tshawb no yog tias NAC tuaj yeem ncua kev qaug zog ntawm cov leeg nqaij thiab txhim kho kev tawm dag zog los ntawm kev txhim kho glutathione homeostasis.
Ntxiv nrog rau glutathione precursors, ib qho ntxiv NAD ntxiv rau cov precursors tuaj yeem ua rau nce qib glutathione. Hauv pawg tswj xyuas kev tshawb fawb hauv xyoo 2020, nws tau pom tias NR ntxiv nrog NAD ntxiv rau qhov chaw tuaj yeem nce qib glutathione ntawm cov ncauj lus. Muaj ob pawg ntawm cov kev kawm hauv qhov kev sim no, cov hluas thiab cov neeg laus. Nws pom tias oxidative kev nyuaj siab ntawm cov neeg laus yog siab thiab glutathione qib qis. Tom qab NR supplementation, qib nad ntawm cov tub ntxhais hluas thiab cov neeg laus nce siab, tab sis tsuas yog cov glutathione ntawm cov neeg laus nce, thiab tsuas yog cov oxidative kev nyuaj siab ntawm cov neeg laus txo qis, uas yog kev pab me ntsis rau cov hluas. Txoj kev tshawb no xaus lus tias NR tsuas yog pab cov neeg uas tsis muaj cov tshuaj antioxidants.
Cov kev tshawb fawb soj ntsuam tau pom tias 4 khob tshuaj yej ntsuab ib hnub rau 8 lub lis piam tuaj yeem ua rau cov tshuaj antioxidants thiab glutathione hauv cov ntshav. Ntxiv nrog rau lipoic acid, selenium, thiab silymarin tuaj yeem nce qib ntawm glutathione hauv lub cev.
Kev txhim kho kev noj zaub mov zoo tuaj yeem ua rau nce qib glutathione. Ua kom tag nrho cov zaub mov, zaub thiab txiv hmab txiv ntoo tuaj yeem nce qib ntawm glutathione. Ntawm lawv, cov khoom noj uas muaj cov organic sulfur antioxidants, suav nrog asparagus, avocado, dib, taum, spinach, thiab papaya, muaj txiaj ntsig zoo tshaj plaws, tab sis cua sov yuav degrade organic sulfur antioxidants, yog li noj nyoos lossis txo cov cua sov thiab lub sijhawm cua sov yuav pab tau.
Tsis lees paub:
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