Khoom piav qhia
Semaglutide 99% Dawb Hmoov CAS 910463-68-2yog glucagon-zoo li peptide-1 receptor agonist (GLP-1 RA) uas tau siv dav hauv kev tswj ntshav qab zib thiab kev rog rog vim nws muaj ntau yam cuam tshuam ntawm kev txo cov ntshav qab zib, poob phaus thiab cov txiaj ntsig ntawm lub plawv.
GLP-1, scientifically hu ua glucagon-zoo li peptide-1, yog lub plab-hlwb peptide secreted los ntawm ileal endocrine hlwb.
Thaum GLP-1 khi rau nws cov receptor, nws ua rau cov tshuaj insulin tso tawm thiab inhibits glucagon tso tawm, yog li txo cov ntshav qab zib.
Cov txheej txheem no suav nrog lwm cov tshuaj tseem ceeb, dipeptidyl enzyme-4, feem ntau hu ua DPP-4. Lub luag haujlwm tseem ceeb ntawm DPP-4 yog degrade GLP-1 hauv lub cev, tswj qhov sib npaug ntawm GLP-1 qib.
Cov kev tshawb fawb tau pom tias cov neeg mob ntshav qab zib hom 2 feem ntau ntsib GLP-1 tsis txaus. Qhov tsis txaus GLP-1 twb tsis muaj zog ntxiv los ntawm cov txiaj ntsig degradation ntawm DPP-4, ua rau cov ntshav qab zib nce siab. Yog li ntawd, txoj hauv kev tseem ceeb ntawm kev txo cov ntshav qab zib muaj ob yam: ib qho yog los tsim DPP-4 inhibitors kom inactivate DPP-4; Lwm qhov yog los tsim biosimilars ntawm GLP-1 los them rau qhov tsis muaj GLP-1.
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COA
| Kev sim | Specifications | Cov txiaj ntsig |
| Qhov tshwm sim | Dawb los yog yuav luag dawb fluffy hmoov | Ua raws |
| Solubility | Soluble hauv dej | Ua raws |
| Cov ntsiab lus dej (Karl Fischer) | Tsawg dua lossis sib npaug li 8.0% | 4.80% |
| Sodium ion | Tsawg dua lossis sib npaug li 5.0% | 2.10% |
| Trifluoroacetic acid | Tsawg dua los yog sib npaug li 0.5% | Tsis Pom |
| Peptide Purity (los ntawm HPLC) | Ntau dua lossis sib npaug li 98.0% | 99.82% |
| Yam khoom | Tag nrho Impurities (%) Tsawg dua lossis sib npaug li 2.0% | 0.18% |
| (los ntawm HPLC) | ||
| Loj tshaj Ib Leeg Impurity (%) Tsawg dua lossis sib npaug li 1.0% | 0.13% | |
| Kab mob | Tsawg dua lossis sib npaug li 10EU / mg | Ua raws |
| Endotoxins | ||
| Tag nrho Aerobic Microbial suav | Tsawg dua lossis sib npaug li 10² cfu / g | Ua raws |
| Tag nrho cov poov xab thiab pwm suav | Tsawg dua lossis sib npaug li 10² cfu / g | Ua raws |
| Assay | 95.0 ~ 105.0% | 101.54% |
| Residual Solvents | Acetonitrile: NMT 410ppm | 138ppm ua |
| Dichloromethane: NMT 600ppm | Tsis Pom | |
| DMF: NMT 880ppm | Tsis Pom | |
| Xaus | Ua raws li kev lag luam specification | |
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Semaglutide zoo ib yam li tej yam ntuj tso GLP-1, tsuas muaj ob qhov sib txawv: (1) alanine amino acid ntawm txoj hauj lwm 8 yog hloov los ntawm -aminoisobutyric acid, uas ua rau cov molecule ntau resistant rau DPP-4 degradation; (2) cov pa roj carbon monoxide tau tshaj tawm ntev dua thiab hloov pauv cov roj ntsha sib txuas ua ke C18 fatty acid diacid rau lysine ntawm txoj hauj lwm 26, yog li txhim kho nws cov albumin binding zog, uas prolongs cov khoom lifespan hauv plasma thiab txo nws lub raum clearance.
Mechanism of Action of Semaglutide 99% Dawb Hmoov CAS 910463-68-2
Semaglutide ua tiav ntau yam teebmeem ntawm lub cev los ntawm kev ua haujlwm ntawm lub cev lub cev incretin GLP-1:
Cov nyhuv hypoglycemic: Thaum cov ntshav qabzib nce siab, nws tshwj xeeb activates GLP-1 receptors ntawm pancreatic cells, txhawb kev tso tshuaj insulin; Tib lub sijhawm, nws inhibits glucagon secretion los ntawm pancreatic cells, txo qis cov piam thaj hauv siab, yog li kev tswj hwm cov ntshav qabzib hauv ob sab nrog kev pheej hmoo ntawm hypoglycemia.
Cov txiaj ntsig poob phaus: Nws ua rau lub plab zom mov qeeb, ua kom lub siab ntev, thiab txo cov zaub mov noj; nws kuj tswj lub hypothalamic qab los noj mov chaw, txo qab los noj mov tsav, yog li pab nyob rau hauv yuag poob.
Kev tiv thaiv kab mob plawv: Nws tuaj yeem txhim kho vascular endothelial muaj nuj nqi, txo cov ntshav siab, txo cov lus teb inflammatory, thiab txo cov kev pheej hmoo ntawm cov kab mob plawv loj (xws li myocardial infarction, stroke, thiab plawv plawv tuag) hauv cov neeg mob ntshav qab zib hom 2 thiab kab mob plawv.
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:sales4@faithfulbio.com
vim li cas xaiv peb
Peb lub Hoobkas
Pob
Shipping Txoj Kev
|
Tsheb thauj mus los |
Shipping txoj kev |
Cargo hnyav xav tau |
Qhov zoo |
|
3-7 hnub |
DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, |
Haum rau qis dua 50kg. |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, thiab cov neeg muas zaub nyob rau hauv cov teb chaws Europe thiab America muaj peev xwm txaus siab rau xa cov khoom ncaj qha los ntawm ob qhov chaw. |
|
7-15 hnub |
Los ntawm Cua |
Haum rau ntau tshaj 50kg. |
|
|
15-60 hnub |
Los ntawm Hiav Txwv |
Haum rau ntau tshaj 500kg. |
Xa koj Cov Lus Nug kom paub meej ntxiv, Nyem email:sales4@faithfulbio.com
FAQ
01. Semaglutide 99% Dawb Powder CAS 910463-68-2 ua haujlwm li cas?
02. Dab tsi yog cov kev mob tshwm sim ntawm Semaglutide 99% White Powder CAS 910463-68-2?
Cov kev mob tshwm sim feem ntau yog me me thiab muaj xws li xeev siab, ntuav, raws plab, cem quav, mob plab, kub siab, thiab belching. Cov tsos mob no feem ntau txo qis thaum lub cev yoog.
03. Kuv tuaj yeem yuav Semaglutide 99% Dawb Powder CAS 910463-68-2 qhov twg?
Cim npe nrov: semaglutide 99% dawb hmoov cas 910463-68-2, Tuam Tshoj, lwm tus neeg, manufacturers, hoobkas, customized, lag luam wholesale, yuav, nqe, tej, ntshiab, tsim, luv nqi, kev muag, Tshuag, dawb qauv, raw hmoov, raw khoom, ua nyob rau hauv Suav teb