Vosoritide Acetate CAS 1480724-61-5

vosoritide Taw qhia

Xi'an Faithful BioTech Co., Ltd. yog ib qho export -oriented biotechnology thiab chemical trading tuam txhab headquartered nyob rau hauv Xi'an, Shaanxi Province, Suav teb. Founded hauv 2018, lub tuam txhab tsom mus rau kev muab tshuaj intermediates, cog extracts, zaub mov additives, thiab pub cov khoom xyaw rau lub ntiaj teb no B2B lag luam.

Raws li ib tug ntshiv, tus neeg muab khoom, peb siv nruj zoo tswj kom ntseeg tau batch stability thiab ua raws. Nrog rau pab pawg muag khoom thoob ntiaj teb, peb muab cov nqi sib tw heev, lub sijhawm xa khoom tuaj yeem ntseeg tau, thiab ib qho - nres cov kev pabcuam xa tawm.

Peb cov khoom tau dav nkag mus rau cov kws kho mob, kev noj qab haus huv ntxiv, tshuaj pleev ib ce, thiab cov khoom noj khoom haus hauv Tebchaws Europe, North America, Southeast Asia, thiab Middle East.

Nws yog C-hom natriuretic peptide analogue tsim los ntawm BioMarin Pharmaceutical Company. Nws txoj kev tshawb fawb tau ua raws li cov qauv ntawm C-hom natriuretic peptide hauv tib neeg lub cev, thiab tau hloov kho kom tsim tau. Nws tau raug pom zoo muag hauv ntau lub tebchaws thiab cheeb tsam suav nrog EU thiab Asmeskas, thiab tau xa daim ntawv thov rau npe hauv Suav teb. Nyob rau tib lub sijhawm, nws tau raug lees paub tias yog cov khoom lag luam menyuam ntsuag. CAS Nr .: 1480724-61-5; nws cov mis molecular yog C176H290N56O51S3; thiab nws tus lej EINECS yog 917891-350-1.Vosoritide acetate hmoovFeem ntau yog tsom rau cov menyuam yaus uas muaj chondrodysplasia, uas yog tshwm sim los ntawm kev hloov pauv hauv FGFR3 noob thiab ua rau muaj kev loj hlob ntawm pob txha. Nyob rau hauv cov nqe lus ntawm nws cov hom kev ua, vosoritide tuaj yeem simulate lub cev taw qhia cov molecules hauv lub cev thiab khi rau cov receptors tshwj xeeb ntawm chondrocytes, yog li inhibiting cov kev ua haujlwm dhau FGFR3, txo cov nyhuv inhibitory ntawm kev loj hlob ntawm pob txha, txhawb kev loj hlob ib txwm thiab ossification ntawm chondrocytes kev loj hlob txhua xyoo, thiab kev loj hlob ntawm cov menyuam yaus. Tsis tas li ntawd, cov kev tshawb fawb soj ntsuam ntsig txog tseem tab tom sim nthuav nws daim ntawv thov mus rau lwm hom kab mob skeletal dysplasia.

Lub hom phiaj ntawm vosoritide yog dab tsi?

Vosoritide acetate hmoovbelongs rau C-hom natriuretic peptide analogues. Nws lub luag haujlwm tseem ceeb ntawm kev ua haujlwm yog txhawm rau qhib cov natriuretic peptide receptor 2 (NPR2), txhawb nqa kev loj hlob thiab kev sib txawv ntawm chondrocytes, ua kom lub hom phiaj ntawm cov pob txha loj hlob, thiab optimizing lub xeev ntawm pob txha loj hlob thiab kev loj hlob.
Cov tshuaj no tsuas yog siv tau rau chondrodysplasia los ntawm kev hloov pauv hauv fibroblast kev loj hlob receptor 3 (FGFR3) noob. Qhov no kuj yog qhov feem ntau ntawm cov kab mob skeletal dysplasia tsis meej hauv kev kho mob. Rau cov neeg mob uas muaj tus kab mob no, nws tuaj yeem ua rau muaj txiaj ntsig zoo rau kev loj hlob txhua xyoo, pab txhawb kev loj hlob ntawm qhov siab, thiab txhim kho lub cev lub cev pob txha, txhim kho lub cev kev loj hlob teeb meem.
Ntau qhov kev sim tshuaj tsis ntev los no tau lees paub ntxiv tias cov khoom no kuj muaj kev cuam tshuam zoo rau me me chondrodysplasia (tsawg phosphatase hom chondrodysplasia), txhim kho qhov kev loj hlob ntawm cov neeg mob, qhov siab qhov ntev, thiab kev loj hlob ntawm caj npab, muab kev txhim kho txhim khu kev qha rau qhov tsis tshua muaj skeletal dysplasia.

vosoritide txhim kho pob txha loj hlob li cas?

Lub core mechanism uasVosoritide acetate hmoovtxhim kho pob txha loj hlob yog los ntawm kev ncaj qha antagonizing lub overactive FGFR3 signaling txoj kev nyob rau hauv chondrodysplasia, yog li tso lub "braking" nyhuv ntawm txoj kev no rau cov pob txha loj hlob.
Tshwj xeeb, nws txoj kev nqis tes ua tuaj yeem muab faib ua cov kauj ruam tseem ceeb hauv qab no:
Lub hom phiaj khi thiab ua kom txoj hauv kev: Vosoritide, raws li C-hom natriuretic peptide analogue, tuaj yeem khi thiab qhib cov natriuretic peptide receptor 2 ntawm qhov chaw ntawm chondrocytes. Qhov kev khi no yuav nce qib ntawm Cyclic guanosine monophosphate hauv cov hlwb.
Antagonizing ntau inhibition ntawm FGFR3: Hauv cov neeg mob uas muaj chondrodysplasia, FGFR3 noob kev hloov pauv ua rau muaj qhov txawv txav ntawm nws txoj kev taw qhia. Kev ua haujlwm ntawm NPR2 thiab nws qhov chaw qis qis cGMP qhia meej meej tuaj yeem cuam tshuam thiab tawm tsam qhov teeb meem FGFR3 overactive. Qhov no yog sib npaug rau tso tawm qhov muaj zog inhibition ntawm FGFR3 ntawm chondrocyte proliferation thiab sib txawv.
Txhawb kev endochondral ossification: Thaum lub "brake" ntawm FGFR3 raug tso tawm, cov chondrocyte precursors nyob rau hauv lub phaj loj hlob tuaj yeem rov muaj peev xwm loj hlob thiab muaj peev xwm sib txawv, yog li txhawb cov synthesis thiab maturation ntawm pob txha mos matrix. Cov txheej txheem no ncaj qha txhawb txoj kev loj hlob ntawm endochondral ossification, uas yog, chondrocytes tau maj mam hloov los ntawm osteoblasts, tsim cov pob txha tshiab, thiab thaum kawg ua tiav qhov kev loj hlob ntawm cov pob txha ntev.

MF ntawm Vosoritide

Specification

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Muaj ntau txoj kev xa khoom rau koj xaiv

Peb lub zog:

Peb lub tuam txhab tau dhau los ntawm FDA thiab ISO19001 kev tswj hwm qhov system ntawv pov thawj. Thiab peb muaj kev koom tes nrog kev cog lus nrog ntau lub Hoobkas thiab chaw kuaj hauv Suav teb, Peb lub tuam txhab tuaj yeem muabVosoritide acetate hmoovthiab lwm yam ntawm tus nqi zoo dua. Yog tias koj txaus siab, thov sau ib tsab ntawv.
Peb tsis tsuas yog muaj qhov tshwj xeeb zoo hauv kev thauj mus los, tab sis kuj txhawb ntau txoj kev them nyiaj, txawm tias koj siv nyiaj US, euros, Australian las, lossis cov nyiaj hauv zos los ntawm Singapore, Malaysia, Thaib, thiab lwm yam. Peb kuj tuaj yeem txhawb cov txiaj ntsig hauv zos hauv cov cheeb tsam thiab cov tebchaws no. Tsis tas li ntawd, peb kuj txhawb nqa cov npav hauv txhab nyiaj (credit cards, thiab lwm yam) rau kev them nyiaj.

FAQ:

Q1: Dab tsi yog qhov tshwm sim tsis zoo thaum siv Vosoritide?
Cov kev mob tshwm sim ntau dua yog qhov tshwm sim hauv zos, xws li liab, khaus, thiab mob me; Tsis tas li ntawd, kev poob qis hauv ntshav siab, xeev siab, thiab mob pob qij txha tuaj yeem tshwm sim. Feem ntau ntawm cov tsos mob no yog mob me thiab tuaj yeem daws tau ntawm lawv tus kheej.
Q2: Vosoritide puas tuaj yeem pab cov neeg mob kom ncav cuag qhov siab ntawm cov tib neeg ib txwm?

Nws tsis tuaj yeem ncav cuag qhov siab nruab nrab ntawm cov pej xeem. Nws tuaj yeem nce qhov kev loj hlob txhua xyoo thiab txhim kho qhov kev loj hlob, tab sis nws yog ib qho kev kho mob es tsis yog kho. Yuav muaj qhov sib txawv ntawm tus kheej hauv qhov siab kawg, thiab ntev - lub sijhawm ua raws - yuav tsum tau ntsuas qhov ntsuas.

Q3: Lub raum ua haujlwm cuam tshuam li cas rau kev siv Vosoritide?

Peptide tshuaj muaj feem xyuam rau lub raum. Cov neeg uas muaj lub raum tsis ua haujlwm yuav tsum tau soj ntsuam kom zoo. Kev siv tsis pom zoo rau cov neeg uas muaj lub raum tsis ua haujlwm hnyav. Thaum noj tshuaj, kev saib xyuas lub raum ua haujlwm - cov ntsuas ntsuas yog tsim nyog.

Tsis lees paub: Cov ntaub ntawv luam tawm ntawm lub vev xaib no los ntawm Is Taws Nem, tsis tau txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm cov ntsiab lus. Thov ua tib zoo saib kom paub qhov txawv. Tsis tas li ntawd, cov khoom muab los ntawm peb lub tuam txhab tsuas yog siv rau kev tshawb fawb tshawb fawb. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv tsis raug.

Yog tias koj txaus siab rau peb cov khoom, lossis muaj cov lus qhia tseem ceeb ntawm peb cov khoom lossis tsis txaus siab rau cov khoom tau txais,

Nyem email:sales6@faithfulbio.comLos yog WhatsApp:+86 17782780648

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