mu-Conotoxin Taw Qhia
Xi'an Faithful BioTech Co., Ltd. yog ib qho export -oriented biotechnology thiab chemical trading tuam txhab headquartered nyob rau hauv Xi'an, Shaanxi Province, Suav teb. Founded hauv 2018, lub tuam txhab tsom mus rau kev muab tshuaj intermediates, cog extracts, zaub mov additives, thiab pub cov khoom xyaw rau lub ntiaj teb no B2B lag luam.
Raws li ib tug ntshiv, tus neeg muab khoom, peb siv nruj tswj xyuas kom ntseeg tau batch stability thiab ua raws. Nrog rau pab pawg muag khoom thoob ntiaj teb, peb muab cov nqi sib tw heev, lub sijhawm xa khoom tuaj yeem ntseeg tau, thiab ib qho - nres cov kev pabcuam xa tawm.
Peb cov khoom tau dav nkag mus rau cov kws kho mob, kev noj qab haus huv ntxiv, tshuaj pleev ib ce, thiab cov khoom noj khoom haus hauv Tebchaws Europe, North America, Southeast Asia, thiab Middle East.
XEP-018 hmoovtsis yog ib yam khoom, tab sis ib pawg ntawm polypeptide co toxins tau los ntawm cov venom ntawm tropical marine snails. Nws yog tsim los ntawm 6 L-Cysteine molecules txuas los ntawm disulfide bonds los tsim cov qauv ruaj khov. CAS: 936616-33-0; Cov mis mos molecular: C92H139N35O28S6; Molecular hnyav: 2375.71; EINECS: 606{15}}757-9. Cov co toxins no tuaj yeem khi nrog kev sib raug zoo siab thiab thaiv cov kab hluav taws xob-gated sodium, yog li cuam tshuam nrog kev ua haujlwm ntawm cov hlab ntsha lossis cov leeg nqaij. Hauv kev tshawb fawb, nws yog siv los ua cov cuab yeej molecule rau kev paub qhov txawv ntawm sodium channel subtypes; ntawm daim ntawv thov, vim nws cov kev xaiv rau qhov mob ntsig txog cov kab mob sodium, nws tau suav tias yog ib qho tseem ceeb ntawm cov hmoov lead ua rau tsis yog opioid analgesics, thiab ob peb txoj kev tshawb fawb kuj tau koom nrog cov leeg nqaij thiab kev tu tawv nqaij.
Lub luag haujlwm ntawm mu-conotoxin yog dab tsi?
XEP-018 hmoovyog ib yam khoom uas tau txheeb xyuas thiab ua kom muaj kev sib txuas ua ke nrog cov leeg nqaij muaj zog heev -txo cov teebmeem. Nws ua rau cov neeg siv tau txais kev tiv thaiv tam sim -wrinkle teebmeem thiab yog siv dav hauv cov khoom siv los tiv thaiv -wrinkle. Mu-conotoxin yog ib qho peptide heev uas nkag mus tau zoo, muaj kev ruaj ntseg siab, thiab tshwj xeeb rau cov leeg nqaij kom ua tiav kev so. Los ntawm thaiv cov hluav taws xob xa hluav taws xob ntawm cov hlab ntsha- cov leeg, nws sai sai plam wrinkles thiab rejuvenates ntawm daim tawv nqaij, ua rau nws zoo li hluas dua.
Lub mechanism ntawm kev ua ntawm mu-conotoxin yog dab tsi?
Cov txheej txheem ua haujlwm ntawm mu-conotoxin tuaj yeem raug suav hais tias yog qhov tshwj xeeb "molecular blocking" nyhuv. Nws cov qauv molecular yog nruj nreem kaw los ntawm peb khub ntawm disulfide daim ntawv cog lus, tsim kom muaj kev sib haum xeeb, ua rau nws paub meej thiab khi rau qhov chaw receptor (site 1) ntawm sab nraud ntawm qhov hluav taws xob -gated sodium channel pore. Los ntawm lub cev embedding, nws thaiv txoj kev permeation ntawm sodium ions. Qhov kev khi no sib npaug rau kev teeb tsa qhov kev tsis sib haum xeeb ntawm qhov nkag ntawm cov ion ntws, tiv thaiv sodium ion influx, cuam tshuam cov txheej txheem depolarization ntawm cov cell membrane, thiab thaum kawg inhibiting kev ua ntawm neural excitation los yog nqaij contraction. Nws yog tsim nyog sau cia tias txawv subtypes ntawmXEP-018 hmoovmuaj qhov sib txawv ntawm qhov sib txawv ntawm cov sodium channel subtypes los ntawm cov ntaub so ntswg sib txawv (xws li cov leeg -hom NaV1.4 lossis mob- cuam tshuam NaV1.7). Qhov kev xaiv no yog los ntawm qhov tseeb spatial sib txuam ntawm cov khoom seem hauv nws cov amino acid ib ntus thiab thaj av pore channel, ua rau lawv ua haujlwm zoo tshaj plaws rau kev kawm txog kev ua haujlwm ntawm sodium channel subtypes thiab muab cov kev cuam tshuam meej molecular hauv paus rau kev txhim kho cov khoom lag luam tshuaj tua kab mob.
MF ntawm mu-conotoxin
| CAS | 936616-33-0 |
| Cov mis mos molecular | C92H139N35O28S6 |
| Molecular hnyav | 2375.71 |
| EINECS | 606-757-9 |
| Qhov ntom | 1.71 ± 0.1g / cm3 |
Specification
| Yam khoom | Specification | Kev tshwm sim |
| Qhov tshwm sim | hmoov dawb | Ua raws |
| Solubility | Qhia | Soluble hauv H2O |
| Purity (HPLC) | Ntau dua lossis sib npaug li 95% | 98.00% |
| Counter Ion | Qhia | Acetic acid |
| Loj spectrum | 2375.7 ±1.0 | 2375.7 |
| Xaus | Ua raws li kev lag luam specification | |
Nyem email:sales6@faithfulbio.comLos yog WhatsApp:+86 17782780648
Muaj ntau txoj kev xa khoom rau koj xaiv
| Tsheb thauj mus los | Shipping txoj kev | Cargo hnyav xav tau | Qhov zoo |
| 3-7 hnub | DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, UPS, USPS, FedEx, TNT, EMS |
Haum rau qis dua 50kg. International qhov rooj rau qhov rooj nthuav qhia |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, thiab cov neeg siv khoom hauv Tebchaws Europe thiab Asmeskas tuaj yeem txaus siab xa khoom ncaj qha los ntawm ob qhov chaw no. |
| 7-15 hnub | Los ntawm Cua | Haum rau ntau tshaj 50kg. ceev thiab pheej yig dua rau kev txiav txim loj |
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| 15-60 hnub | Los ntawm Hiav Txwv | Haum rau ntau tshaj 500kg. Kev xa khoom pheej yig tshaj plaws |
Peb lub zog:
Peb lub tuam txhab tau dhau los ntawm FDA thiab ISO19001 kev tswj hwm qhov system ntawv pov thawj. Thiab peb muaj kev koom tes nrog kev cog lus nrog ntau lub Hoobkas thiab chaw kuaj hauv Suav teb, Peb lub tuam txhab tuaj yeem muabXEP-018 hmoovthiab lwm yam ntawm tus nqi zoo dua. Yog tias koj txaus siab, thov sau ib tsab ntawv.
Peb tsis tsuas yog muaj qhov tshwj xeeb zoo hauv kev thauj mus los, tab sis kuj txhawb ntau txoj hauv kev them nyiaj, txawm tias koj siv nyiaj US, euros, Australian las, lossis cov nyiaj hauv zos los ntawm Singapore, Malaysia, Thaib, thiab lwm yam. Peb kuj tuaj yeem txhawb cov txiaj ntsig hauv zos hauv cov cheeb tsam thiab cov tebchaws no. Tsis tas li ntawd, peb kuj txhawb nqa cov npav hauv txhab nyiaj (credit cards, thiab lwm yam) rau kev them nyiaj.
FAQ:
Q1: Puas yog mu-conotoxin nqus tau yooj yim los ntawm daim tawv nqaij?
Lub transdermal permeability ntawm ntshiab peptide molecules yog txwv. Cov kev daws teeb meem niaj hnub no yog siv cov tswv yim xws li liposome encapsulation, microemulsion systems, lossis ionic electroosmosis los pab lawv nkag mus los ntawm stratum corneum barrier.
Q2: Puas yuav mu-conotoxin ua rau tuag tes tuag taw cov leeg ntawm lub ntsej muag?
Tsis yog. Nws yog tsim los khaws cia kwv yees li 5% ntawm cov sodium tam sim no, uas yog sib npaug rau kev muab cov leeg me me "ua pa", yog li lub ntsej muag ntawm lub ntsej muag tseem nyob ib puag ncig.
Q3: Nws yuav siv sij hawm ntev npaum li cas kom pom cov txiaj ntsig tom qab siv nws?
Tom qab daim ntawv thov hauv zos, pom cov txiaj ntsig tam sim ntawm kev txo cov kab zoo feem ntau tshwm sim li ob peb feeb mus rau 2 teev. Qhov no yog hom kev txo qis "stant" kab.
Tsis lees paub: Cov ntaub ntawv luam tawm ntawm lub vev xaib no los ntawm Is Taws Nem, tsis tau txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm cov ntsiab lus. Thov ua tib zoo saib kom paub qhov txawv. Tsis tas li ntawd, cov khoom muab los ntawm peb lub tuam txhab tsuas yog siv rau kev tshawb fawb tshawb fawb. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv tsis raug.
Yog tias koj txaus siab rau peb cov khoom, lossis muaj cov lus qhia tseem ceeb ntawm peb cov khoom lossis tsis txaus siab rau cov khoom tau txais,
Nyem email:sales6@faithfulbio.comLos yog WhatsApp:+86 17782780648
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