Sulfasalazine Taw Qhia
Xi'an Faithful BioTech Co., Ltd. yog ib qho export -oriented biotechnology thiab chemical trading tuam txhab headquartered nyob rau hauv Xi'an, Shaanxi Province, Suav teb. Founded hauv 2018, lub tuam txhab tsom mus rau kev muab tshuaj intermediates, cog extracts, zaub mov additives, thiab pub cov khoom xyaw rau lub ntiaj teb no B2B lag luam.
Raws li ib tug ntshiv, tus neeg muab khoom, peb siv nruj tswj xyuas kom ntseeg tau batch stability thiab ua raws. Nrog rau pab pawg muag khoom thoob ntiaj teb, peb muab cov nqi sib tw heev, lub sijhawm xa khoom tuaj yeem ntseeg tau, thiab ib qho - nres cov kev pabcuam xa tawm.
Peb cov khoom tau dav nkag mus rau cov kws kho mob, kev noj qab haus huv ntxiv, tshuaj pleev ib ce, thiab cov khoom noj khoom haus hauv Tebchaws Europe, North America, Southeast Asia, thiab Middle East.
Sulfasalazine zoo li cov txiv kab ntxwv hmoov. CAS tus lej yog 599-79-1; nws cov mis molecular yog C18H14N4O5S; nws qhov hnyav molecular yog 398.39; nws tus lej EINECS yog 209-974-3. Nws yog ib hom Sulfanilamide antibacterial khoom. Keeb xeeb, nws tau siv rau cov kab mob plab hnyuv, uas yog Crohn tus kab mob thiab cov kab mob plab hnyuv, nrog rau ob qho kev tiv thaiv kab mob thiab tshuaj tua kab mob. Tom qab xyoo 1970, nws tau pom tias nws tuaj yeem txo qhov mob pob qij txha, o, thiab tawv nqaij hauv ankylosing spondylitis, thiab tseem tuaj yeem txo cov ntshav qab zib IgA thiab lwm yam kev ntsuas ntsuas. Nws yog tshwj xeeb tshaj yog tsim nyog rau kev txhim kho peripheral mob caj dab nyob rau hauv cov neeg mob uas muaj ankylosing spondylitis thiab muaj cov nyhuv ntawm kev tiv thaiv rov tshwm sim thiab alleviating qhov txhab ntawm tus kab mob no thaum nws muaj teeb meem nrog anterior uveitis. Nrog rau kev nce qib ntawm kev tshawb fawb, nws tau maj mam siv rau kev mob caj dab rheumatoid. Txog tam sim no,Sulfasalazine API Hmoovtau siv dav hauv kev kho mob rheumatoid mob caj dab thiab cov kab mob txha caj qaum.
Dab tsi yog qhov mechanism ntawm kev txiav txim ntawm Sulfasalazine?
Sulfasalazine yog ib qho kev npaj cov khoom lag luam nruab nrab. Nws txoj kev ua tau zoo yog ua tiav los ntawm kev sib koom ua ke ntawm ntau yam teebmeem xws li lub hom phiaj tso plab hnyuv, txo qhov mob, thiab kev tswj hwm ntawm lub cev. Tom qab kev tswj hwm qhov ncauj, feem ntau ntawm cov khoom siv raw yuav tsis decomposed thiab absorbed nyob rau hauv lub plab thiab cov hnyuv, tab sis yuav mus txog rau txoj hnyuv. Lub azo reductase secreted los ntawm lub colonic flora yuav ua txhaum lub azo daim ntawv cog lus thiab faib nws mus rau hauv ob active metabolite Cheebtsam: 5-Aminosalicylic acid thiab Sulfapyridine.
Rau kev tshawb fawb scenarios muaj feem xyuam rau txoj hnyuv o xws li ulcerative colitis thiab Crohn tus kab mob, 5-Aminosalicylic acid plays lub luag hauj lwm tseem ceeb. Nws tuaj yeem nyob twj ywm ntawm thaj tsam cuam tshuam ntawm txoj hnyuv, thaiv kev tsim cov pro- cov tshuaj tiv thaiv kab mob xws li Prostaglandin E2 thiab LEUKOTRIENE F4, thiab txo qis cov kab mob hauv zos mucosa. Hauv kev mob caj dab rheumatoid-txog kev sim, Sulfasalazine uas nkag mus rau hauv cov hlab ntsha nrog rau cov qauv raw khoom yuav tswj lub cev tiv thaiv kab mob hauv lub cev, ua kom lub cev tsis muaj zog ntau dhau thiab cov lus teb tsis zoo ntawm lub cev, thiab feem ntau yog siv rau cov neeg laus thiab cov menyuam yaus hauv kev tshawb fawb txog kev mob caj dab.
Ntxiv rau, covSulfasalazine API HmoovKuj tseem cuam tshuam rau tib neeg Folic acid metabolic txoj hauv kev, sib tw khi rau cov enzymes cuam tshuam nrog Folic acid metabolism, ntxiv kev pabcuam hauv kev tswj hwm kev tiv thaiv kab mob ntau dhau. Los ntawm kev cia siab rau txoj kev ua haujlwm tshwj xeeb ntawm kev txo qis hauv zos ntawm kev mob plab hauv plab hnyuv thiab kev tswj hwm kev tiv thaiv kab mob los ntawm kev faib ua haujlwm ntawm kev sib koom tes, cov khoom siv raw no tuaj yeem hloov kho rau ob qho tib si hauv vitro thiab hauv vivo kev tshawb fawb ntsig txog txoj hnyuv thiab kev sib koom ua ke.
Vim li cas Sulfasalazine tuaj yeem kho ob qho tib si enteritis thiab mob caj dab?
Sulfasalazine API Hmoovmuaj peev xwm ib txhij alleviate ob leeg plab hnyuv o thiab pob qij txha. Qhov laj thawj tseem ceeb nyob hauv nws cov khoom tshwj xeeb thiab dual -txoj haujlwm mechanism. Nws yog cov khoom siv raw preformulated uas tsis siv ncaj qha thaum nkag mus rau hauv lub cev. Hloov chaw, nws ncav cuag txoj hnyuv thiab, nyob rau hauv qhov kev txiav txim ntawm txoj hnyuv, decomposes rau hauv ob yam khoom siv, 5-Aminosalicylic acid thiab Sulfapyridine. Ob yam khoom no ua haujlwm sib cais los daws qhov mob tshwm sim hauv ntau qhov chaw.
Ntawm lawv, 5-Aminosalicylic acid tsis yog nqus los ntawm cov hnyuv thiab tuaj yeem nyob rau ntawm qhov chaw ntawm lub plab mucosa rau lub sijhawm ntev. Los ntawm inhibiting zus tau tej cov pro- inflammatory mediators xws li Prostaglandin E2 thiab LEUKOTRIENE F4, nws tshwj xeeb alleviates lub zos inflammatory mob nyob rau hauv tej yam kev mob xws li ulcerative colitis thiab Crohn tus kab mob. Lub decomposed Sulfapyridine tuaj yeem nkag mus rau tib neeg txoj kev ncig thiab tswj lub cev tsis muaj zog ntawm tag nrho cov theem, calming down qhov txawv txav thiab cov lus teb ntau dhau, yog li hais txog kev tiv thaiv kev tiv thaiv kab mob ntsig txog mob caj dab rheumatoid.
Txawm hais tias txoj hnyuv o thiab kev sib koom ua ke muaj qhov sib txawv ntawm qhov chaw pib thiab tshwm sim sab nraud, lawv cov ntsiab lus ob qho tib si los ntawm kev tiv thaiv kab mob ua rau tsis sib haum xeeb hauv kev mob. Sulfasalazine tso siab rau ob qho - hom kev ua ntawm kev mob hauv zos hauv cov hnyuv thiab kev tiv thaiv kab mob, uas ua rau nws hloov mus rau ob hom kev mob - ntsig txog kev tshawb fawb scenarios. Qhov kev sib koom tes no thiab ob qho -txoj kev them nyiaj tus yam ntxwv kuj ua rau nws yog cov khoom siv raw khoom qub uas sib npaug ntawm txoj hnyuv thiab kev sib koom tes tshawb fawb.
MF ntawm Sulfasalazine
| CAS | 599-79-1 |
| Cov mis mos molecular | C18H14N4O5S |
| Molecular hnyav | 398.39 |
| EINECS | 209-974-3 |
| Melting point | 260-265 degree |
| Boiling point | 689.3 ± 65.0 degree |
| Qhov ntom | 1.3742 |
Specification
| Yam khoom | Specification | Kev tshwm sim | |||
| Kev piav qhia | Txiv kab ntxwv hmoov | Ua raws | |||
| Kev txheeb xyuas | IR | IR spectrum zoo ib yam nrog Gabapentin RS | Ua raws | ||
| HPLC | Ua raws li RT ntawm lub ncov loj hauv HPLC nrog USP Gabapentin WPS | Ua raws | |||
| PH | 6.5~8.0 | 7.4 | |||
| Dej | Tsawg dua los yog sib npaug li 0.5% | 0.04% | |||
| Residue ntawm ignition | Tsawg dua lossis sib npaug li 0.1% | 0.03% | |||
| Cov hlau hnyav | Tsawg dua lossis sib npaug li 0.002% | <0.002% | |||
| Tag nrho impurities | Tsawg dua los yog sib npaug li 0.5% | 0.003% | |||
| Assay | 98.0%~102.0% | 99.90% | |||
| Xaus | Ua raws li kev lag luam specification | ||||
Nyememail:sales6@faithfulbio.com Los yog WhatsApp:+86 17782780648
Muaj ntau txoj kev xa khoom rau koj xaiv
| Tsheb thauj mus los | Shipping txoj kev | Cargo hnyav xav tau | Qhov zoo |
| 3-7 hnub | DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, UPS, USPS, FedEx, TNT, EMS |
Haum rau qis dua 50kg. International qhov rooj rau qhov rooj nthuav qhia |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, thiab cov neeg siv khoom hauv Tebchaws Europe thiab Asmeskas tuaj yeem txaus siab xa khoom ncaj qha los ntawm ob qhov chaw no. |
| 7-15 hnub | Los ntawm Cua | Haum rau ntau tshaj 50kg. ceev thiab pheej yig dua rau kev txiav txim loj |
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| 15-60 hnub | Los ntawm Hiav Txwv | Haum rau ntau tshaj 500kg. Kev xa khoom pheej yig tshaj plaws |
Peb lub zog:
Peb lub tuam txhab tau dhau los ntawm FDA thiab ISO19001 kev tswj hwm qhov system ntawv pov thawj. Thiab peb muaj kev koom tes nrog kev cog lus nrog ntau lub Hoobkas thiab chaw kuaj hauv Suav teb, Peb lub tuam txhab tuaj yeem muabSulfasalazine API Hmoovthiab lwm yam ntawm tus nqi zoo dua. Yog tias koj txaus siab, thov sau ib tsab ntawv.
Peb tsis tsuas yog muaj qhov tshwj xeeb zoo hauv kev thauj mus los, tab sis kuj txhawb ntau txoj hauv kev them nyiaj, txawm tias koj siv nyiaj US, euros, Australian las, lossis cov nyiaj hauv zos los ntawm Singapore, Malaysia, Thaib, thiab lwm yam. Peb kuj tuaj yeem txhawb cov txiaj ntsig hauv zos hauv cov cheeb tsam thiab cov tebchaws no. Tsis tas li ntawd, peb kuj txhawb nqa cov npav hauv txhab nyiaj (credit cards, thiab lwm yam) rau kev them nyiaj.
FAQ:
Q1: Kev sib txuas ntawm folic acid thiab sulfasalazine?
Vim tias cov khoom no muaj cov tshuaj tiv thaiv -folic acid, nws tuaj yeem cuam tshuam nrog kev nqus thiab metabolism ntawm folic acid. Kev siv sijhawm ntev - tuaj yeem ua rau tsis muaj folic acid, uas tuaj yeem ua rau megaloblastic anemia. Yog li ntawd, nws yog ib qho tsim nyog yuav tau noj cov tshuaj folic acid ntxiv los tiv thaiv qhov no.
Q2: Puas yog sulfasalazine muab rho tawm los ntawm cov xwm txheej lossis cov tshuaj sib xyaw ua ke?
Nws yog kiag li chemically synthesized. Nws yog tsim los ntawm kev sib txuas ntawm ob lub molecules ntawm Sulfapyridine thiab 5-Aminosalicylic acid los ntawm diazo coupling cov tshuaj tiv thaiv, thiab nws tsis yog muab rho tawm los ntawm cov tsiaj lossis nroj tsuag.
Q3: Puas tuaj yeem siv sulfasalazine thaum lactation?
Sulfasalazine thiab nws cov metabolites tuaj yeem nkag rau hauv cov kua mis me me. Txawm hais tias qhov kev pheej hmoo tsis tshua muaj rau feem ntau tag nrho - cov menyuam mos noj qab haus huv, nws tuaj yeem ua rau hemolysis hauv cov menyuam mos uas tsis muaj G6PD. Yog li ntawd, thaum lub sij hawm lactation, lawv siv yuav tsum tau ceev faj nyob rau hauv kev ntsuam xyuas ntawm ib tug kws kho mob.
Tsis lees paub: Cov ntaub ntawv luam tawm ntawm lub vev xaib no los ntawm Is Taws Nem, tsis tau txhais hais tias lub vev xaib no pom zoo nrog nws cov kev xav lossis lees paub qhov tseeb ntawm cov ntsiab lus. Thov ua tib zoo saib kom paub qhov txawv. Tsis tas li ntawd, cov khoom muab los ntawm peb lub tuam txhab tsuas yog siv rau kev tshawb fawb tshawb fawb. Peb tsis muaj lub luag haujlwm rau qhov tshwm sim ntawm kev siv tsis raug.
Yog tias koj txaus siab rau peb cov khoom, lossis muaj cov lus qhia tseem ceeb ntawm peb cov khoom lossis tsis txaus siab rau cov khoom tau txais,
Nyememail:sales6@faithfulbio.com Los yog WhatsApp:+86 17782780648
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