Khoom Taw Qhia
Rasagiline mesylate hmoovyog ib qho irreversible monoamine oxidase inhibitor. Nws tuaj yeem txo qhov decomposition ntawm dopamine los ntawm kev xaiv inhibiting monoamine oxidase, thiab nce qib ntawm dopamine nyob rau hauv lub hlwb striatum. Kev nce qib dopamine tuaj yeem txo cov tsos mob ntawm tus kab mob Parkinson. Raws li cov tshuaj tseem ceeb, rasagiline mesylate plays lub luag haujlwm tseem ceeb hauv kev kho mob. Nws cov khoom tshwj xeeb pharmacokinetic thiab daim ntawv thov dav ua rau nws ua tau zoo hauv kev kho mob ntawm ntau yam kab mob.
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| Rasagiline mesylate hmoov Daim duab | Rasagiline mesylate hmoov MF |
Khoom siv
Rasagiline mesylate hmoovyog ib hom tshiab ntawm MAO-B inhibitor siv los kho tus kab mob Parkinson tam sim ntawd. Piv nrog rau thawj tiam monoamine oxidase inhibitors, cov nyhuv inhibitory yog 5 mus rau 10 npaug zog, thiab nws kuj muaj kev txhim kho rau cov neeg mob uas siv cov tshuaj dopa mus sij hawm ntev uas nws cov txiaj ntsig tau poob qis. Tsis tas li ntawd, cov metabolite ntawm rasagiline yog ib qho tsis ua haujlwm tsis muaj tshuaj amphetamine nrog ob peb phiv. Qhov tseem ceeb tshaj, tsis zoo li lwm cov tshuaj tiv thaiv Parkinson, rasagiline mesylate kuj muaj cov nyhuv neuroprotective. Thaum siv cov kev kho mob sib xyaw ua ke, cov txiaj ntsig kho mob ntawm levodopa tuaj yeem ua kom zoo, cov tsos mob tuaj yeem tswj tau zoo dua, thiab cov teeb meem ntawm lub cev tuaj yeem txo qis.
Rasagiline yog ib qho muaj zog, xaiv tau zoo, tsis tuaj yeem hloov pauv monoamine oxidase-B inhibitor uas tuaj yeem cuam tshuam dopamine degradation, nce dopamine tsub zuj zuj, txhawb kev tso tawm dopamine, thiab txhim kho cov tsos mob hauv cov neeg mob PD. Nws muaj cov qauv tshuaj tshiab, lub hom phiaj yog txhawm rau txhim kho qhov tsis txaus ntawm thawj tiam MAO-B inhibitors.
Cov kev tshawb fawb hauv vitro tau lees paub tias cov metabolite ntawm rasagiline, aminoindan, muaj cov nyhuv neuroprotective. Rasagiline yog ib qho kev xaiv zoo heev hauv kev khi rau MAO-B, uas yog qhov kev ncua deb ntawm ob chav nyob nruab nrab ntawm lub nplhaib aromatic thiab N-propargyl davhlau ya nyob twg hauv cov qauv. Tsis tas li ntawd, peb daim ntawv cog lus ntawm pab pawg zoo N-propargylamine yog qhov tseem ceeb los tswj cov nyhuv rasagiline tsis tuaj yeem. Irreversible kev txiav txim txhais tau hais tias qhov kev txiav txim yog sustained, thiab yog li ntawd yuav muab sustained dopaminergic stimulation.
Khoom Specification
| Kuaj | Specification | Kev tshwm sim |
| Kev piav qhia | Dawb rau xim av hmoov | Ua raws |
| Solubility | Yooj yim soluble hauv anhydrous ethanol thiab methanol; me ntsis soluble hauv acetone; | Ua raws |
| Txheeb xyuas | Infrared absorption spectrum ntawm tus qauv yuav tsum ua raws li cov ntaub ntawv siv spectrum. | Raws li kev siv tus qauv spectrum |
| Kev txheeb xyuas cov tshuaj chloride hauv cov tshuaj ethanol kiag li ntawm cov khoom no | Cov tshuaj tiv thaiv zoo | |
| Poob Thaum Qhuav | Tsis ntau tshaj 0.5% | 0.07% |
| Sulfated tshauv | Tsis ntau tshaj 0.1% | 0.05% |
| txheeb ze yam khoom | Impurity B Tsawg dua lossis sib npaug rau 0.15% | Tsis pom |
| Impurity E Tsawg dua lossis sib npaug rau 0.05% | Tsis pom | |
| Tsis paub ib qho impurity Tsawg dua lossis sib npaug rau 0.10% | 0.03% | |
| Tag nrho impurities | 0.10% | |
| Residue Solvents (GC) | Isopropyl cawv Tsawg dua lossis sib npaug li 5000ppm | 2 15ppm |
| Ethyl acetate Tsawg dua lossis sib npaug li 5000ppm | 24 2 hmu | |
| Chloroform Tsawg dua lossis sib npaug li 60ppm | Tsis pom | |
| Kev ntsuam xyuas (HPLC) | Tsis pub tsawg dua 98.5% | 99.75% |
| (Nyob ntawm Dried Basis) | ||
| Xaus | Ua raws li tus qauv kev lag luam | |
Yuav Ua Li Cas Kom Tau Txais Cov QauvRasagiline mesylate hmoov?
Txais tos xa ib qho kev nug rausunny@faithfulbio.comtxhua lub sijhawm rau tus qauv dawb yog tias koj xav tau APIRasagiline mesylate hmoov.
Qhov zoo tshaj plaws Rasagiline mesylate hmoov Chaw tsim tshuaj paus thiab tsum
Faithfulbio muaj kev paub dhau los hauv kev xa tawm cov ntaub ntawv raw thiab tau tsim kev sib raug zoo thiab kev koom tes ntev nrog peb cov neeg siv khoom. Peb ib txwm muab cov khoom zoo thiab kev pabcuam ua ntej. Yog tias koj muaj cov khoom siv raw khoom xav tau, thov hu rau peb. Peb tuaj yeem lees paub qhov kev txiav txim nrog koj raws li koj qhov yuav khoom ntau. Peb kuj txhawb peb txoj kev koom tes thawj zaug pib los ntawm cov qauv. Tsis tas li ntawd, peb txoj kev thauj mus los sai thiab nyab xeeb kuj ua rau koj tshem tawm cov teeb meem ntawm kev lis kev cai.
Peb muaj kev ntseeg siab ntawm peb cov khoom zoo, tab sis yog tias muaj teeb meem tom qab muag, peb yuav teb sai li sai tau thiab daws lawv nrog koj txoj hauv kev zoo tshaj plaws.
Vim Li Cas Xaiv FaithfulbioRasagiline mesylate hmoov?
Faithfulbio tshwj xeeb hauvRasagiline mesylate hmoovrau ntau xyoo, peb muab cov khoom ntawm tus nqi sib tw, thiab peb cov khoom yog qhov zoo tshaj plaws, vim tias peb nruj heev hauv cov khoom tsim thiab kev sim, thiab muaj kev ua tiav thiab paub tab. Tsis tas li ntawd, peb cov neeg ua haujlwm Cov lus hais rau cov khoom muaj kev sib tw heev.
Muaj ntau txoj kev xa khoom rau koj xaiv
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Tsheb thauj mus los |
Shipping txoj kev |
Cargo hnyav xav tau |
Qhov zoo |
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3-7 hnub |
DHL, Lub teb chaws Yelemees DHL, Lub teb chaws Yelemees DPD, |
Haum rau qis dua 50kg. |
Peb muaj warehouses nyob rau hauv lub teb chaws Yelemees thiab California, teb chaws USA, |
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7-15 hnub |
Los ntawm Cua |
Haum rau ntau tshaj 50kg. |
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15-60 hnub |
Los ntawm Hiav Txwv |
Haum rau ntau tshaj 500kg. |
ua siab zoo ceeb toom:SivRasagiline mesylate hmoovrau kev tshawb fawb nkaus xwb. Txhua lub tebchaw muaj kev pheej hmoo. Thov nrog koj tus kws kho mob tham thiab kawm txog cov kev tshawb fawb muaj ua ntej siv. Tsis tas li ntawd, cov lus piav qhia saum toj no ntawm qhov sib xyaw yog los ntawm cov ntaub ntawv online. Yog tias muaj kev ua txhaum cai, thov hu rau peb kom tshem tawm.
Qhov twg Yuav Rasagiline mesylate hmoov?
Cia li xa email rausunny@faithfulbio.com, lossis xa koj qhov yuav tsum tau ua hauv daim ntawv hauv qab, peb muaj kev pabcuam txhua lub sijhawm!
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